Correlation Analysis of Risk Factors in Patients with Post-menopause Osteoporosis_Chinese Journal of Evidence-Based Medicine

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Yueyang Hospital Affiliated to the Shanghai University of TCM, Shanghai 200437, China;

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Keywords：

Primary osteoporosis; Risk factors; Correlation Analysis

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Objective 　To explore the correlation of risk factors affecting the L2-4BMD level in patients with post-menopausal osteoporosis.
Methods 　Ninety-two patients with post-menopausal osteoporosis were surveyed with a retrospective questionnaire. We used the findings to set up a multiple stepwise regression model and perform correlation analysis with L2-4BMD levels as the dependent variable and risk factors as the independent variables.
Results 　Assuming that age has a definite effect on the L2-4BMD level of menopausal women, menopausal age limit, history of milk drinking, menopausal age, menarche age, fracture history and bend-back entered into the multiple stepwise regression equation.
Conclusions 　Menopausal age limit, history of milk drinking, menopausal age, menarche age, fracture history, and bend-back influence patients with menopausal osteoporosis.The menopausal age limit is especially important. Awareness of the risk factors of osteoporosis should be raised.

Citation： SHI Xiao,YANG Wenhong. Correlation Analysis of Risk Factors in Patients with Post-menopause Osteoporosis. Chinese Journal of Evidence-Based Medicine, 2006, 06(10): 756-759. doi: Copy

1.	中国老年学学会骨质疏松委员会骨质疏松诊断标准学科组.中国人原发性骨质疏松症诊断标准(试行).中国骨质疏松杂志, 1999; 5(1): 1–3.
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4.	朴俊红, 庞莲萍, 刘忠厚, 等. 中国人口状况及原发性骨质疏松症诊断标准和发生率. 中国骨质疏松杂志, 2002; 8(1): 1–7.
5.	黄干, 廖二元, 伍贤平, 等. 老年妇女体重指数与骨密度和骨超声传导速度的相关性研究. 中华物理医学与康复杂志, 2003; 25(1): 23–26.
6.	刘建民, 赵红燕, 宁光等. 绝经前健康妇女的身体组成成分与骨密度的关系. 中国医学科学院学报, 2003; 25(3): 250–253.
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9.	Jiang FY, Lao San, Long FY, et al. Study on Correlation Among Age,Menopausal Years and Bone Metabolite Index. Journal of Practical Obstetrics and Gynecology, 2003; 19(2): 91–92.
10.	Yang DZ, Yang Hui, Liu Fang, et al. Effects of mechanical load on peak bone mass. Chinese Journal of Osteoporosis, 2003,9（2）：124–127.
11.	Trivitayaratana,-W; rivitayaratana, -P. Limb measurements for height and bone mineral density estimation. J-Med-Assoc-Thai, 2001; 84(2):S505–509.
12.	Versluis RG, Papapoulos SE. Clinical risk factors as predictors of postmenopausal osteoporosis in general practice. Br-J-Gen-Pract，2001; 51(471): 806–810.
13.	Piao JH, Pang LP, Liu ZH, et al. Chinese population, the diagnostic criteria of primary osteoporosis and the incidence of osteoporosis in china. Chinese Journal of Osteoporosis, 2002; 8(1): 1–7.
14.	Nourhashemi F，Rolland Y，Vellas B．Prevention of falls and their consequence. Presse Med, 2000; 29: 1249–1254.
15.	Runge M. Diagnosis of the risk of accidental falls in the eldedy. Ther Umsch, 2002; 59: 351–358．.
16.	Parkkari J, Kannus P, Palvanen M, et al. Majority of hip fractures occur as a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture study with 206 consecutive patients. Calcif Tissue Int, 1999; 65: 183–187.
17.	Grabiner MD, Pavol MJ, Owings TM. Can fall-related hip fractures be prevented by characterizing the biomechanical mechanisms of failed recovery? Endocrine, 2002; 17: 15–20.
18.	Teegarden D, Lyle RM, Proulx WR, et a1. Previous milk consumption associated with greater bone density in young women. Am J Clin Nutr, 1999; 69: 1014–1017.
19.	Bonjour JP, Chevalley T, Ammann P, et a1．Gain in bone mineral mass in prepubertal girls 3.5 years after discontinuation of calcium supplementation: a follow-up study. Lancet, 2001; 358: 1208–1212.
20.	Reid IR, Ames RW, Evans MC, et a1. Long-term effects of calcium supplementation on bone loss and fractures in postmenopausual women: a randomized controlled trial. Am J Med, 1995; 98: 331–335.
21.	Huang G, Liao ey, Wu XP, et al. The relationship between body mass index and bone mineral density and conduction velocity of sound in bone in elderly women. Chinese Journal of Physical Medicine and Retabulitation, 2003; 25(1): 23–26.
22.	Fox MX, Magaziner J, Hawkes WG, et al. Loss of bone density and lean body mass after hip fracture. Osteoporos Int, 2000; 11: 31–35.
23.	Liu JM, Zhao HY, Ning G, et al. Relationship between Body Composition and Bone Mineral Density in Healthy Premenopausal Women. Acta Academiae Medicinae Sinicae, 2003; 25(3):250-253.

1. 中国老年学学会骨质疏松委员会骨质疏松诊断标准学科组.中国人原发性骨质疏松症诊断标准(试行).中国骨质疏松杂志, 1999; 5(1): 1–3.
2. 蒋凤艳，劳山，龙凤宜等.年龄、绝经年限与骨代谢指标相关性研究.实用妇产科杂志, 2003; 19(2): 91–92.
3. 杨定焯, 杨惠, 刘芳, 等. 力学负荷对峰值骨量影响的初步研究. 中国骨质疏松杂志, 2003; 9(2): 124–127.
4. 朴俊红, 庞莲萍, 刘忠厚, 等. 中国人口状况及原发性骨质疏松症诊断标准和发生率. 中国骨质疏松杂志, 2002; 8(1): 1–7.
5. 黄干, 廖二元, 伍贤平, 等. 老年妇女体重指数与骨密度和骨超声传导速度的相关性研究. 中华物理医学与康复杂志, 2003; 25(1): 23–26.
6. 刘建民, 赵红燕, 宁光等. 绝经前健康妇女的身体组成成分与骨密度的关系. 中国医学科学院学报, 2003; 25(3): 250–253.
7. Diagnosis guideline of Chinese primary osteoporosis (temporary). Chinese geraeology academy, Osteoporosis committee. Diagnosis standard groupof osteoporosis.Chinese Journal of Osteoporosis, 1999; 5(1): 1–3.
8. Fujta Y, Katsumata K, Unno A, et al. Factors affecting peak bone density in Japanese women. Calcif tissue Int, 1999; 64(2): 107–111.
9. Jiang FY, Lao San, Long FY, et al. Study on Correlation Among Age,Menopausal Years and Bone Metabolite Index. Journal of Practical Obstetrics and Gynecology, 2003; 19(2): 91–92.
10. Yang DZ, Yang Hui, Liu Fang, et al. Effects of mechanical load on peak bone mass. Chinese Journal of Osteoporosis, 2003,9（2）：124–127.
11. Trivitayaratana,-W; rivitayaratana, -P. Limb measurements for height and bone mineral density estimation. J-Med-Assoc-Thai, 2001; 84(2):S505–509.
12. Versluis RG, Papapoulos SE. Clinical risk factors as predictors of postmenopausal osteoporosis in general practice. Br-J-Gen-Pract，2001; 51(471): 806–810.
13. Piao JH, Pang LP, Liu ZH, et al. Chinese population, the diagnostic criteria of primary osteoporosis and the incidence of osteoporosis in china. Chinese Journal of Osteoporosis, 2002; 8(1): 1–7.
14. Nourhashemi F，Rolland Y，Vellas B．Prevention of falls and their consequence. Presse Med, 2000; 29: 1249–1254.
15. Runge M. Diagnosis of the risk of accidental falls in the eldedy. Ther Umsch, 2002; 59: 351–358．.
16. Parkkari J, Kannus P, Palvanen M, et al. Majority of hip fractures occur as a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture study with 206 consecutive patients. Calcif Tissue Int, 1999; 65: 183–187.
17. Grabiner MD, Pavol MJ, Owings TM. Can fall-related hip fractures be prevented by characterizing the biomechanical mechanisms of failed recovery? Endocrine, 2002; 17: 15–20.
18. Teegarden D, Lyle RM, Proulx WR, et a1. Previous milk consumption associated with greater bone density in young women. Am J Clin Nutr, 1999; 69: 1014–1017.
19. Bonjour JP, Chevalley T, Ammann P, et a1．Gain in bone mineral mass in prepubertal girls 3.5 years after discontinuation of calcium supplementation: a follow-up study. Lancet, 2001; 358: 1208–1212.
20. Reid IR, Ames RW, Evans MC, et a1. Long-term effects of calcium supplementation on bone loss and fractures in postmenopausual women: a randomized controlled trial. Am J Med, 1995; 98: 331–335.
21. Huang G, Liao ey, Wu XP, et al. The relationship between body mass index and bone mineral density and conduction velocity of sound in bone in elderly women. Chinese Journal of Physical Medicine and Retabulitation, 2003; 25(1): 23–26.
22. Fox MX, Magaziner J, Hawkes WG, et al. Loss of bone density and lean body mass after hip fracture. Osteoporos Int, 2000; 11: 31–35.
23. Liu JM, Zhao HY, Ning G, et al. Relationship between Body Composition and Bone Mineral Density in Healthy Premenopausal Women. Acta Academiae Medicinae Sinicae, 2003; 25(3):250-253.

Chinese Journal of Evidence-Based Medicine

Correlation Analysis of Risk Factors in Patients with Post-menopause Osteoporosis

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