The Pleomorphic Liposarcoma of Galactophore_West China Medical Journal

Authors：

LIU Qian ¹ , DING Wuwu ¹ , HAN Qi ² , WU Ning ¹ , Meng Hong. ¹

1. Department of Pathology; 2. Department of Ultrasonography, the People’s Hospital of Deyang City, Deyang, Sichuang 618000, P. R. China;

Corresponding author：

Keywords：

脂肪肉瘤; 乳腺; 鉴别诊断

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目的　探讨乳腺脂肪肉瘤的临床病理特点及鉴别诊断。方法　分析2010年3月收治的1例乳腺多形性脂肪肉瘤的临床表现、组织病理学特征及免疫表型特点，并复习相关文献。结果　肿瘤由高级别多形性肉瘤和数量不等的多形性脂肪母细胞组成。免疫组织化学：肿瘤细胞呈S-100蛋白阳性表达、CD34灶性阳性表达，细胞角蛋白、上皮膜抗原、巨噬细胞表面抗原、结蛋白、平滑肌肌动蛋白、肌调节蛋白、肌浆蛋白、CD31均呈阴性表达。结论　乳腺脂肪肉瘤是一种少见的原发于乳腺的间叶源性肿瘤，诊断上应首先排除乳腺化生性癌和恶性叶状肿瘤伴脂肪肉瘤分化，应依据形态学特点和免疫组织化学结果进行鉴别。

Citation： LIU Qian,DING Wuwu,HAN Qi,WU Ning,Meng Hong.. The Pleomorphic Liposarcoma of Galactophore. West China Medical Journal, 2012, 27(10): 1462-1464. doi: Copy

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13.	Gallagher KE, Wu HH. Pathologic quiz case: unilateral breast mass in a 75-year-old woman[J]. Arch Pathol Lab Med, 2001, 125(11): 1503-1504.
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1. 　Blanchard DK, Reynolds CA, Grant CS, et al. Primary nonphylloides breast sarcomas[J]. Am J Surg, 2003, 186(4): 359-361.
2. 　Adem C, Reynolds C, Ingle JN, et al. Primary breast sarcoma: clinicopathologic series from the mayo clinic and review of the literature[J]. Br J Cancer, 2004, 91(2): 237-241.
3. 　Neumann E. Beitrage zur casuistik der brusdrusengeshwulste[J]. Virchows Arch Path Anat,1862, 24: 316-328.
4. 　Foust RL, Berry AD 3rd, Moinuddin SM. Fine needle aspiration cytology of liposarcoma of the breast: a case report[J]. Acta Cytol, 1994, 38(6): 957-960.
5. 　Carpanelli JB, Lempel G, Gatta C. Report of a Case of liposarcoma of the mammary gland[J]. Sem Med, 1963, 123（25）: 321-322.
6. 　Nandipati KC, Nerkar H, Satterfield J, et al. Pleomorphic liposarcoma of the breast mimicking breast abscess in a 19-year-old postpartum female: a case report and review of the literature[J]. Breast J, 16(5): 537-540.
7. 　Pant I, Kaur G, Joshi SC, et al. Myxoid liposarcoma of the breast in a 25-year-old female as a diagnostic pitfall in fine needle aspiration cytology: report of a rare case[J]. Diagn Cytopathol, 2008, 36(9): 674-677.
8. 　常红波, 曹红梅, 贾化霞. 男性乳腺脂肪肉瘤1例的超声表现[J]. 中国超声医学杂志, 2003, 19(11): 851.
9. 　莫爵飞. 男性脂肪肉瘤一例报道[J]. 实用癌症杂志, 1998, 13(3): 234.
10. 　Padmanabhan V, Dahlstrom JE, Chong GC, et al. Phyllodes tumor with lobular carcinoma in situ and liposarcomatous stroma[J]. Pathology, 1997, 29(2): 224-226.
11. 　Vivian JB, Tan EG, Frayne JR, et al. Bilateral liposarcoma of the breast[J]. Aust N Z J Surg, 1993, 63(8): 658-659.
12. 　Hummer CD, Burkart TJ. Liposarcoma of the breast. A case of bilateral involvement[J]. Am J Surg, 1967, 113(4): 558-561.
13. 　Gallagher KE, Wu HH. Pathologic quiz case: unilateral breast mass in a 75-year-old woman[J]. Arch Pathol Lab Med, 2001, 125(11): 1503-1504.
14. 　Austin RM, Dupree WB. Liposarcoma of the breast: a clinicopathologic study of 20 cases[J]. Hum Pathol, 1986, 17(9): 906-913.
15. 　Pandey M, Mathew A, Abraham EK, et al. Primary sarcoma of the breast[J]. J Surg Oncol, 2004, 87(3): 121-125.

West China Medical Journal

The Pleomorphic Liposarcoma of Galactophore

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