目的 探讨延髓肿瘤的治疗策略，以达到最佳预后。 方法 回顾分析2007年1月－2010年12月19例延髓肿瘤患者的临床资料，其中18例经外科手术治疗和病理证实，1例通过影像学确诊。 结果 12例血管网状细胞瘤中，11例手术全切，1例手术次全切；2例室管膜瘤均手术全切；2例海绵状血管瘤分别手术全切及伽马刀治疗；3例胶质瘤均手术部分切除。18例手术治疗患者术后神经功能障碍明显好转者13例，无明显变化者3例，2例因术后严重并发症死亡；1例伽马刀治疗患者症状好转。术后随访6～48个月，平均24个月。11例恢复工作，4例生活可自理，2例因肿瘤复发死亡。结论 术前通过MRI检查、术中神经电生理监测及熟练的显微外科技术是外科治疗优势，伽马刀治疗延髓较小肿瘤有着损伤小的优点，因此制定合理的治疗策略有利于提高患者生存质量。
Citation：
HAO De,YANG Xiang,ZHANG Yuekang. Clinical Analysis of Medulla Oblongata Tumor. West China Medical Journal, 2012, 27(6): 885-888. doi:
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| 1. |
Dan SH, James Z, Donlin M. Surgical resection of intrinsic brain steml lesions: an overview[J]. Neurosurgery, 1990, 27(5): 789-798.
|
| 2. |
Chang UK, ChoeWJ, Chung SK, et al. Surgical outcome and prognostic factors of spinal intramedullary ependymomas in adults[J]. J Neurooncol, 2002, 57(2): 133-139.
|
| 3. |
周良辅, 杜固宏, 毛颖, 等. 脑干血管母细胞瘤的诊断和治疗[J]. 中华神经外科杂志, 2004, 20(2): 127-131.
|
| 4. |
Wang C, Zhang J, Liu A, et al. Surgical management of medullary hemangioblastoma. Report of 47 cases [J]. Surg Neurol, 2001, 56(4): 218-227.
|
| 5. |
Weil RJ, Lonser RR, DeVroom HL, et al. Surgical man-agement of brainstem hemangioblastomas in patients withvon Hippel-Lindau disease [J]. J Neurosurg, 2003, 98(1): 95-105.
|
| 6. |
Parker F, Aghakhani N, Ducati LG, et al. Results of micro-surgical treatment of medulla oblongata and spinal cordhemangioblastomas: a comparison of two distinct clinicalpatient groups [J]. J Neurooncol, 2009, 93(1): 133-137.
|
| 7. |
王恩敏, 张南, 王滨江. 伽玛刀治疗血管母细胞瘤临床分析[J]. 中华外科杂志, 2003, 41(9): 516-520.
|
| 8. |
Kohno K, Matsul S, Nishizaki A, et al. Successful total removal of intramedullary hemangiohlastoma from the medulla oblongata[J]. Surg Neurol, 1993, 39(2): 25-30.
|
- 1. Dan SH, James Z, Donlin M. Surgical resection of intrinsic brain steml lesions: an overview[J]. Neurosurgery, 1990, 27(5): 789-798.
- 2. Chang UK, ChoeWJ, Chung SK, et al. Surgical outcome and prognostic factors of spinal intramedullary ependymomas in adults[J]. J Neurooncol, 2002, 57(2): 133-139.
- 3. 周良辅, 杜固宏, 毛颖, 等. 脑干血管母细胞瘤的诊断和治疗[J]. 中华神经外科杂志, 2004, 20(2): 127-131.
- 4. Wang C, Zhang J, Liu A, et al. Surgical management of medullary hemangioblastoma. Report of 47 cases [J]. Surg Neurol, 2001, 56(4): 218-227.
- 5. Weil RJ, Lonser RR, DeVroom HL, et al. Surgical man-agement of brainstem hemangioblastomas in patients withvon Hippel-Lindau disease [J]. J Neurosurg, 2003, 98(1): 95-105.
- 6. Parker F, Aghakhani N, Ducati LG, et al. Results of micro-surgical treatment of medulla oblongata and spinal cordhemangioblastomas: a comparison of two distinct clinicalpatient groups [J]. J Neurooncol, 2009, 93(1): 133-137.
- 7. 王恩敏, 张南, 王滨江. 伽玛刀治疗血管母细胞瘤临床分析[J]. 中华外科杂志, 2003, 41(9): 516-520.
- 8. Kohno K, Matsul S, Nishizaki A, et al. Successful total removal of intramedullary hemangiohlastoma from the medulla oblongata[J]. Surg Neurol, 1993, 39(2): 25-30.
