新生儿高血压的诊治阐述_West China Medical Journal

Authors：

夏利 ,  熊英

Corresponding author：

熊英, Email: zourui13@163.com

Keywords：

新生儿; 高血压; 有创血压; 无创血压; 治疗

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【摘要】新生儿高血压的定义是将在3个不同时间测得的血压高于同日龄新生儿收缩压（SBP）/舒张压（DBP）的95百分位者。其常见病因是肾实质和肾血管病变。治疗上应积极治疗原发病，临床上常用的降压药包括血管紧张素转化酶抑制剂（Angiotensin-converting enzyme inhibitors，ACEI）、利尿剂、钙通道阻滞剂、β受体阻滞剂。多数患儿可达到临床治愈，少数迁延为慢性高血压，需长期治疗。

Citation： 夏利,熊英. 新生儿高血压的诊治阐述. West China Medical Journal, 2010, 25(7): 1388-1390. doi: Copy

1.	Seliem WA, Michael C, Shadbolt B. Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up[J]. Pediatr Nephrol, 2007, 22: 2081-2087.
2.	Watkinson M. Hypertension in the newborn baby[J]. Arch Dis Child Fetal Neonatal Ed, 2002, 86(2): F78-F81.
3.	Majid R, Kathleen AM. Systemic hypertension[J]. Clin Perinatol, 1992, 19(1): 121-137.
4.	范芳秀, 刘红锋, 董敏, 等. 足月新生儿7日内血压变化范围及临界值[J]. 实用儿科临床杂志, 2006, 21(4): 235-236.
5.	Kent AL, Kecskes Z, Shandbolt B, et al. Normative blood pressure data in the early neonatal period[J]. Pediatr Nephrol, 2007, 22: 1335-1341.
6.	Stebor AD. Basic principles of noninvasive blood pressure measurement in infants[J]. Advances in Neonatal Care, 2005, 5(5): 252-261.
7.	Bagga A, Jain R, Vijayakumar M, et al. Evaluation and Management of Hypertension[J]. Indian Pediatrics, 2007, 44: 103-121.
8.	王吉宏, 赵志萍, 王丁香. 听诊法血压测量的方法学和影响因素[J]. 中华高血压杂志, 2008, 16: (10): 955-958.
9.	Nwankwo M, Lorenz J, Gardiner J. A standard protocol for blood pressure measurement in the newborn[J]. Pediatrics, 1997, 99(6): E10.
10.	陈安, 杜立中, 韦翊. 新生儿血压节律及窒息或早产因素对血压节律影响的研究[J]. 2001, 16(12): 729-731.
11.	付华斌, 韩亚光, 穆华. 动态血压监测的研究进展[J]. 华北国防医药, 2009, 21(5): 78-80.
12.	Rajpoot DK, Duel B, Thayer K, et al. Medically resistant neonatal hypertension: revisiting the surgical causes[J]. Perinatol, 1999, 19(8)part1, 582-583.
13.	Arar MY, Hogg RJ, Arant BS, et al. Etiology of sustained hypertension in children in the southwestern United States[J]. Pediatr Nephrol, 1994, 8(2): 186-189.
14.	李明珠. 新生儿高血压的诊断与治疗[J]. 临床儿科杂志, 2008, 26(3): 265-267.
15.	李晓红. 原发性高血压与胰岛素抵抗的相关性研究[J]. 临床和实验医学杂志, 2009, 8(6): 29-30.
16.	Flynn JT. Neonatal hypertension: diagnosis and management[J]. Pediatr Nephrol, 2000, 14(4): 332-341.
17.	韩恵君, 宋红梅, 魏珉. 新生儿高血压[J]. 新生儿科杂志, 2004, 19(1): 44-47.
18.	Mihai L. Neonatal hypertension--diagnostic and therapeutic approach[J]. Rev Med Chir Soc Med Nat Iasi, 2007, 111(3): 593-600.
19.	郑爱东, 吴可贵. 儿童原发性高血压的临床研究进展[J]. 福建医药杂志, 2009, 31(4): 89-91.
20.	Kilian K. Hypertension in neonates causes and treatments[J]. Perinatal and Neonatal Nursing, 2003, 17(1): 65-74.
21.	Simonetti GD, Rizzi M, Donadini R, et al. Effects of antihypertensive drugs on blood pressure and proteinuria in childhood[J]. J Hypertens, 2007, 25: 2370-2376.
22.	von Schnakenburg C, Krüger M. Note of caution for the use of sodium nitroprusside in neonatal hypertension[J]. Pediatr Nephrol, 2004, 19: 1307.
23.	梁志强, 林振浪, 陈鲜威. 早产儿高血压的临床特点[J]. 临床儿科杂志, 2006, 24(6): 503-504.
24.	Flynn JT. Evaluation and management of hypertension in childhood[J]. Prog Pediatr Cardiol, 2001, 12(2): 177-188.

1. Seliem WA, Michael C, Shadbolt B. Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up[J]. Pediatr Nephrol, 2007, 22: 2081-2087.
2. Watkinson M. Hypertension in the newborn baby[J]. Arch Dis Child Fetal Neonatal Ed, 2002, 86(2): F78-F81.
3. Majid R, Kathleen AM. Systemic hypertension[J]. Clin Perinatol, 1992, 19(1): 121-137.
4. 范芳秀, 刘红锋, 董敏, 等. 足月新生儿7日内血压变化范围及临界值[J]. 实用儿科临床杂志, 2006, 21(4): 235-236.
5. Kent AL, Kecskes Z, Shandbolt B, et al. Normative blood pressure data in the early neonatal period[J]. Pediatr Nephrol, 2007, 22: 1335-1341.
6. Stebor AD. Basic principles of noninvasive blood pressure measurement in infants[J]. Advances in Neonatal Care, 2005, 5(5): 252-261.
7. Bagga A, Jain R, Vijayakumar M, et al. Evaluation and Management of Hypertension[J]. Indian Pediatrics, 2007, 44: 103-121.
8. 王吉宏, 赵志萍, 王丁香. 听诊法血压测量的方法学和影响因素[J]. 中华高血压杂志, 2008, 16: (10): 955-958.
9. Nwankwo M, Lorenz J, Gardiner J. A standard protocol for blood pressure measurement in the newborn[J]. Pediatrics, 1997, 99(6): E10.
10. 陈安, 杜立中, 韦翊. 新生儿血压节律及窒息或早产因素对血压节律影响的研究[J]. 2001, 16(12): 729-731.
11. 付华斌, 韩亚光, 穆华. 动态血压监测的研究进展[J]. 华北国防医药, 2009, 21(5): 78-80.
12. Rajpoot DK, Duel B, Thayer K, et al. Medically resistant neonatal hypertension: revisiting the surgical causes[J]. Perinatol, 1999, 19(8)part1, 582-583.
13. Arar MY, Hogg RJ, Arant BS, et al. Etiology of sustained hypertension in children in the southwestern United States[J]. Pediatr Nephrol, 1994, 8(2): 186-189.
14. 李明珠. 新生儿高血压的诊断与治疗[J]. 临床儿科杂志, 2008, 26(3): 265-267.
15. 李晓红. 原发性高血压与胰岛素抵抗的相关性研究[J]. 临床和实验医学杂志, 2009, 8(6): 29-30.
16. Flynn JT. Neonatal hypertension: diagnosis and management[J]. Pediatr Nephrol, 2000, 14(4): 332-341.
17. 韩恵君, 宋红梅, 魏珉. 新生儿高血压[J]. 新生儿科杂志, 2004, 19(1): 44-47.
18. Mihai L. Neonatal hypertension--diagnostic and therapeutic approach[J]. Rev Med Chir Soc Med Nat Iasi, 2007, 111(3): 593-600.
19. 郑爱东, 吴可贵. 儿童原发性高血压的临床研究进展[J]. 福建医药杂志, 2009, 31(4): 89-91.
20. Kilian K. Hypertension in neonates causes and treatments[J]. Perinatal and Neonatal Nursing, 2003, 17(1): 65-74.
21. Simonetti GD, Rizzi M, Donadini R, et al. Effects of antihypertensive drugs on blood pressure and proteinuria in childhood[J]. J Hypertens, 2007, 25: 2370-2376.
22. von Schnakenburg C, Krüger M. Note of caution for the use of sodium nitroprusside in neonatal hypertension[J]. Pediatr Nephrol, 2004, 19: 1307.
23. 梁志强, 林振浪, 陈鲜威. 早产儿高血压的临床特点[J]. 临床儿科杂志, 2006, 24(6): 503-504.
24. Flynn JT. Evaluation and management of hypertension in childhood[J]. Prog Pediatr Cardiol, 2001, 12(2): 177-188.

West China Medical Journal

新生儿高血压的诊治阐述

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