【摘要】 目的  探讨小儿外科围手术期抗菌药物应用情况，为儿外科临床合理、规范使用抗菌药物提供参考。 方法  随机抽取儿外科2008年1月-2009年10月出院手术病历763份，对抗菌药物的应用情况进行分析。 结果  763份病历显示，患儿均使用了抗菌药物，应用率高达100%。抗菌药物品种应用最多的是青霉素类518例（48.05%），其次为头孢菌素类336例（31.17%），其他抗菌药物（林可霉素类、硝基咪唑类、大环内酯类等）224例（20.78%）。一联用药574例（75.00%），二联用药147例（19.00%），三联及以上用药42例（6.00%）。其中， 99例（12.98%）做过病原学检测，39例有药敏试验依据（5.11%），以G+中的葡萄球菌为主。 结论  小儿外科围手术期抗菌药物目前应用存在一定的不合理，临床应当严格按照《抗菌药物临床应用指导原则》合理、规范使用抗菌药物。
【Abstract】 Objective  To investigate the perioperative use of antibiotics in children’s surgery of our hospital to guide it’s reasonable and normal use. Methods  A total of 763 patients who discharged from our hospital between January 2008 and October 2009 were sampled randomly for statistical analysis regarding the utilization. Results  Of the 763 cases reviewed, all cases (100%) received antibiotics. In terms of the application of antibiotics, penicillins were predominantly used in 518 patients (48.05%), followed by cephalosporins in 336 patients (31.17%) and other antibiotics such as lincomycins nitroimidazoles and macrolides in 224 patients (20.78%). 574 patients (75.00%) received one antibiotic, 147 (19.00%) received two antibiotics and 42(6.00%) received at least three antibiotics concomitantly. Only 99 patients (12.98%) received etiological test and 39 patients (5.11%) received susceptibility test during antibiotic ues, most of them are G+ staphylococcus infected. Conclusion  The perioperative use of antibiotics in our hospital is somewhat unreasonable, thus monitoring closely on which should be performed to promote their reasonable and normal use.

Citation： ZHANG Dan. Perioperative Use of Antibiotics in Children’s Surgery. West China Medical Journal, 2010, 25(8): 1517-1519. doi: Copy