1，3-β-D葡聚糖检测对尿路插管所致真菌感染的诊断价值_West China Medical Journal

Authors：

杨莉萍 ¹ , 曹登成 ²

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Keywords：

1，3-β-D葡聚糖; 尿路插管; 真菌感染

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【摘要】目的 探讨尿路插管所致真菌感染患者的血浆和尿液中1，3-β-D葡聚糖检测的临床意义。方法将2009年1-5月47例尿路插管所致真菌感染患者设为试验组，50例正常健康体检者设为对照组，分别检测其血浆和尿液中1，3-β-D葡聚糖的水平。结果试验组与对照组比较，血浆及尿液中1，3-β-D葡聚糖含量差异有统计学意义（P lt;0.001）；试验组的尿液和血浆中1，3-β-D葡聚糖含量比较，有统计学意义（P lt;0.05），尿液中的1，3-β-D葡聚糖含量高于血浆。结论血浆和尿液1，3-β-D葡聚糖水平检测可作为诊断泌尿系统真菌感染的可靠指标，且尿液样本的诊断价值高于血浆。

Citation： 杨莉萍,曹登成. 1，3-β-D葡聚糖检测对尿路插管所致真菌感染的诊断价值. West China Medical Journal, 2010, 25(8): 1553-1555. doi: Copy

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8.	赵勇, 王红, 任爱民, 等. 血浆β-1, 3-D-葡聚糖对深部真菌感染诊断的研究[J]. 中国真菌学杂志, 2007, 2(4): 202-206.
9.	张建芳, 徐修礼, 樊新, 等. 深部真菌感染患者血浆1-3-β-D葡聚糖检测的临床意义[J]. 中华医院感染学杂志, 2005, 15(3): 354-355.
10.	廖经忠, 刘文恩, 易斌, 等. 血清(1-3)-β-D-葡聚糖检测对深部真菌感染的诊断价值[J]. 实用预防医学, 2009, 16(1): 226-228.

1. 高蕾, 周新. (1, 3)-β-D葡聚糖检测在侵袭性真菌感染中的诊断意义[J]. 中国感染与化疗杂志, 2008, 8(2): 121-125.
2. Mennink-Kersten MA, Donnelly JP, Verweij PE. Detection of circulating galactomannan for the diagnosis and management of invasive aspergillosis[J]. Lancet Infect Dis, 2004, 4(6): 349-357.
3. 孙宝云, 康云平, 滕勇, 等. 肺部真菌感染患者外周血1-3-β-D-葡聚糖水平分析[J]. 中国预防医学杂志, 2009, 10(5): 354-355.
4. Pazos C, Pontón J, Del Palacio A. Contribution of (1, 3)-β-D-glucan chromogenic assay to diagnosis and therapeutic monitoring of invasive aspergillosis in neurpenic adult patients: a comparison with serial screening for circulating galactomannan[J]. J Clin Microbiol, 2005, 43(1): 299-305.
5. Odabasi Z, Mattiuzzi G, Estey E, et al. β-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome[J]. Clin Infect Dis, 2004, 39(2): 199-205.
6. Yoshida K. Recent advances of serodiagnosis for systemic fungal infections[J]. Nippon lshinkin Gakkai Zasshi, 2006, 47(3): 135-142.
7. Kedzierska A. (1, 3)-beta-D-glucan-a new marker for the early serodiagnosis of deep-seated fungal infections in humans[J]. Pol J Microbiol, 2007, 56(1): 3-9.
8. 赵勇, 王红, 任爱民, 等. 血浆β-1, 3-D-葡聚糖对深部真菌感染诊断的研究[J]. 中国真菌学杂志, 2007, 2(4): 202-206.
9. 张建芳, 徐修礼, 樊新, 等. 深部真菌感染患者血浆1-3-β-D葡聚糖检测的临床意义[J]. 中华医院感染学杂志, 2005, 15(3): 354-355.
10. 廖经忠, 刘文恩, 易斌, 等. 血清(1-3)-β-D-葡聚糖检测对深部真菌感染的诊断价值[J]. 实用预防医学, 2009, 16(1): 226-228.

West China Medical Journal

1，3-β-D葡聚糖检测对尿路插管所致真菌感染的诊断价值

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