人工肝支持系统的临床应用_West China Medical Journal

Authors：

胡蓉 ,  陈竹

Corresponding author：

陈竹, Email: 524924478@qq.com

Keywords：

人工肝支持系统; 重型肝炎; 临床应用

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【摘要】人工肝支持系统是一套以血液净化为基础的治疗方法，并在缓解重型肝炎患者的病情、延长其生命、争取肝移植时间等方面取得。现就近年来国内外非生物型人工肝的发展现状及其临床应用作一综述。

Citation： 胡蓉,陈竹. 人工肝支持系统的临床应用. West China Medical Journal, 2010, 25(8): 1571-1573. doi: Copy

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11.	邹春毅, 魏丽艳, 李颖, 等. 人工肝支持系统治疗重型肝病、肝衰竭的疗效及影响因素分析[J]. 透析与人工器官, 2008, 19(3):1-7.
12.	刘燕, 何金秋, 邹正宇, 等. 组合型非生物人工肝治疗重型肝炎合并肝性脑病临床研究[J]. 临床荟萃, 2008, 23(7):495-496.
13.	Pryor HI 2nd, Vacanti JV. The promise of artificial liver replacement[J]. Front Biosci 2008；13:2140-2159.
14.	王宇, 陈洋, 郭仁福, 等. HepG2细胞构成的生物人工肝体外氨与安定的代谢能力[J]. 世界华人消化杂志, 2005, 13(5):648-652.
15.	Rozga J. Liver support technology-an update[J]. Xenotransplantation, 2006, 13(5):380-389.
16.	Demetriou AA, Brown RSJ, Busuttil RW, et al. Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure[J]. Ann Surg, 2004, 239(5):660-670.
17.	Li J, Li LJ, Yu HY, et al. Growth and metablism of human hepatocytes on biomodified collagen poly (lactic-coglycolic acid) three-dimensional scaffold[J]. ASAIO J, 2006, 52(3):321-327.

1. Li LJ, Liu XL, Xu XW, et al. Comparison of plasma exchange with different membrane pore sizes in the treatment of severe viral hepatitis[J]. Ther Apher Dial, 2005, 9(5):396-401.
2. Yonekawa C, Nakae H, Tajimi K, et al. Effectiveness of combining plasma exchange with continuous hemodiafiltration in patients with postoperative Liver failure[J]. Artif Organs 2005, 29 (9):324-328.
3. 车龙, 牛殿吉, 金福东, 等. 血浆吸附治疗高胆红素血症临床观察[J]. 中国危重病急救医学, 2006, 18(1):12.
4. 赵慧媛, 李荣山, 邵珊, 等. 血液灌流对IL-6、TNF-a、CRP的影响[J]. 中国血液净化, 2005, (4)10: 566-568.
5. Pless G, Sauer I M. Bioartificial liver:current statues [J]. Transplant Proc, 2005, 37(9):3893-3895.
6. Laleman W, Wilmer A, Evenepoel P, et al. Review article:non-biological liver support in liver failure[J]. A1iment Pharmocol Ther, 2006, 23:351-363.
7. Onodera K, Sakata H, Yonekawa M, et al. Artificial liver support at present and in the future[J]. J Artif Organs, 2006, 9(1):17-28.
8. Rifai K, Ernst T, Kretschmer U, et al. Removal selectivity of Prometheus:A new extracorporeal liver support device[J]. World J Gastroenterol, 2006, 12(6):940-944.
9. 向德栋, 王宇明, 毛青, 等. 非生物人工肝对慢性重型肝炎肝功能支持效果评价[J]. 传染病信息, 2008, 21(2):90-91.
10. 王堂明, 李玉龙, 邱波, 等. 人工肝支持系统治疗慢性重型肝炎疗效观察[J]. 肝脏, 2008, 13(4): 320-322.
11. 邹春毅, 魏丽艳, 李颖, 等. 人工肝支持系统治疗重型肝病、肝衰竭的疗效及影响因素分析[J]. 透析与人工器官, 2008, 19(3):1-7.
12. 刘燕, 何金秋, 邹正宇, 等. 组合型非生物人工肝治疗重型肝炎合并肝性脑病临床研究[J]. 临床荟萃, 2008, 23(7):495-496.
13. Pryor HI 2nd, Vacanti JV. The promise of artificial liver replacement[J]. Front Biosci 2008；13:2140-2159.
14. 王宇, 陈洋, 郭仁福, 等. HepG2细胞构成的生物人工肝体外氨与安定的代谢能力[J]. 世界华人消化杂志, 2005, 13(5):648-652.
15. Rozga J. Liver support technology-an update[J]. Xenotransplantation, 2006, 13(5):380-389.
16. Demetriou AA, Brown RSJ, Busuttil RW, et al. Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure[J]. Ann Surg, 2004, 239(5):660-670.
17. Li J, Li LJ, Yu HY, et al. Growth and metablism of human hepatocytes on biomodified collagen poly (lactic-coglycolic acid) three-dimensional scaffold[J]. ASAIO J, 2006, 52(3):321-327.

West China Medical Journal

人工肝支持系统的临床应用

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