【摘要】 目的 总结凯纷与曲马多在患儿扁桃体和腺样体手术的镇痛效果及不良反应。 方法 2009年4月-2009年10月,将60例行扁桃体和腺样体摘除术患儿,随机分为A组(凯芬组)、B组(曲马多组)及C组(对照组)。A组于麻醉插管后手术开始前10 min静注凯纷1mg/kg,B组静注曲马多1 mg/kg,C组静注等量生理盐水。观察其拔管时间、苏醒期反应、恢复期疼痛评分、低血氧症的发生、恶心呕吐及术野区出血情况。 结果 3组患儿的拔管时间、术后低氧血症的发生率均无统计学意义。监测治疗室(PACU)中A、B组患儿的苏醒期躁动发生率及疼痛评分明显低于C组(P lt;0.05),且A组无恶心呕吐发生,B、C组恶心呕吐的发生率分别为11.1%和5%。 结论 凯纷及曲马多用于小儿扁桃体和腺样体手术均可获得良好的镇痛及镇静效果,并减少了拔管期的躁动发生且不增加拔管时间及术后低血氧症。但凯纷组患儿没有恶心呕吐发生,更适用于小儿的扁桃体;腺样体;手术。
Citation:
陈琦,陶岩,鄂爽,李丹,吴钢. 凯纷与曲马多在患儿扁桃体和腺样体术中的镇痛效果. West China Medical Journal, 2010, 25(10): 1883-1885. doi:
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- 2. Sümpelmann R, Münte S. Postoperative analgesia in infants and children[J]. Curr Opin Anaesthesiol, 2003, 16(3): 309-313.
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- 4. 庄心良, 曾因明, 陈伯銮. 现代麻醉学[M]. 3版. 北京: 人民卫生出版社, 2006: 1439.
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