Clinical Analysis of 96 Patients with Hemorrhagic Transformation after Cerebral Infarction_West China Medical Journal

Authors：

QING Shaohua , GU Chengwu , HE Hui.

Deparement of Neurology，Suining Central Hospital，Suining Sichuan 629000，China;

Corresponding author：

Keywords：

脑梗死; 出血转化; 临床分析

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目的：探讨脑梗死出血转化(HT)的病因，发生率，临床表现和影像学特点及预后。方法：对我院2002年1月至2008年7月96例脑梗死出血转化患者进行回顾性分析。结果：糖尿病、高血压、心房纤颤、血脂异常、大面积脑梗死是HT的主要病因，其发生率为20.3%，第一周为62.5%，第二周为31.2%，两周后为6.3%，其临床表现为头痛、呕吐、肢体无力加重、意识障碍加深，CT或MRI表现为非血肿型与血肿型，死亡率为16.7%。结论：对神经症状及体征加重的患者，尤其是大面积脑死患者，应及早查复查CT或MRI，有利于HT的早期诊治。

Citation： QING Shaohua,GU Chengwu,HE Hui.. Clinical Analysis of 96 Patients with Hemorrhagic Transformation after Cerebral Infarction. West China Medical Journal, 2009, 24(2): 269-270. doi: Copy

1.	Bayramoglu M，Karatas M，Leblebici B，et al.Hemorrhagic transformation in stroke patients[J].Am J Phys Med Rehabil，2003，82(1)：48-52..
2.	Silva Y，Leira R，Tejada J，et al.Molecular signatures of vascular injury are associated with early growth of intracerebral hemorrhage[J].Stroke.2005，36(1)：86-91..
3.	Tong DC，Adami A，Moseley ME，et al.Relationship between apparent diffusion coefficient and subsequent hemorrhagic transformation following acute ischemic stroke[J].Stroke，2000，31(10)：2378-2384..
4.	Kerenyi L，Kardos L，Szasz J，et al.Factors influencing hemorrhagic transformation in ischemic stroke：a clinicopathological comparison[J].Eur J Neurol，2006，13(11)：1251-1255..
5.	段辽江，齐中华，李胜.出血性脑梗死52例临床分析[J].大连医科大学学报，2007，29(2)：151-152..
6.	Castellanos M，Sobrino T，Millan M，et al.Serum cellular fibronectin and matrix metalloproteinase9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke：a multicenter confirmatory study[J].Stroke.2007，38(6)：1855-1859..
7.	Montaner J，Molina CA，Monasterio J，et al.Matrix metalloproteinase9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke[J].Circulation，2003，107(4)：598-603.

1. Bayramoglu M，Karatas M，Leblebici B，et al.Hemorrhagic transformation in stroke patients[J].Am J Phys Med Rehabil，2003，82(1)：48-52..
2. Silva Y，Leira R，Tejada J，et al.Molecular signatures of vascular injury are associated with early growth of intracerebral hemorrhage[J].Stroke.2005，36(1)：86-91..
3. Tong DC，Adami A，Moseley ME，et al.Relationship between apparent diffusion coefficient and subsequent hemorrhagic transformation following acute ischemic stroke[J].Stroke，2000，31(10)：2378-2384..
4. Kerenyi L，Kardos L，Szasz J，et al.Factors influencing hemorrhagic transformation in ischemic stroke：a clinicopathological comparison[J].Eur J Neurol，2006，13(11)：1251-1255..
5. 段辽江，齐中华，李胜.出血性脑梗死52例临床分析[J].大连医科大学学报，2007，29(2)：151-152..
6. Castellanos M，Sobrino T，Millan M，et al.Serum cellular fibronectin and matrix metalloproteinase9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke：a multicenter confirmatory study[J].Stroke.2007，38(6)：1855-1859..
7. Montaner J，Molina CA，Monasterio J，et al.Matrix metalloproteinase9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke[J].Circulation，2003，107(4)：598-603.

West China Medical Journal

Clinical Analysis of 96 Patients with Hemorrhagic Transformation after Cerebral Infarction

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