• Department of Breast and Thyroid Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;
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目的:通过体外研究探讨化疗剂量对乳腺癌治疗效果的影响。方法:通过手术取材和肿瘤组织原代细胞体外培养技术,对96例乳腺癌患者进行体外药物敏感性检测。结果:乳腺癌晚期患者比早期患者的耐药风险明显增加(P<0.05),乳腺癌复发患者比原发患者具有更强的多药耐药能力(P<0.01);增加化疗药物剂量仍然可以提高大多数耐药患者的治疗效果(P<0.01)。结论:大剂量化疗方案对晚期和复发性乳腺癌患者有帮助。

Citation: LI Zhi,LIU Chunping,SONG Haiping,et al.. In VitroChemosensitivity Test of Primary and Recurrent Breast Cancer. West China Medical Journal, 2009, 24(2): 374-376. doi: Copy