The Clinical Trial of the Same dose Ropivacaine after Lumbar Plexus with Sciatic Nerve Block_West China Medical Journal

Authors：

XU Hongwei , ZHOU Ji , ZHANG Jinfeng , et al

Department of Anesthesiology,West china hospital,Sichuan University,Chengdu 610041,China;

Corresponding author：

Keywords：

罗哌卡因; 神经阻滞; 腰丛; 坐骨神经

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目的:观察相同剂量不同浓度的罗哌卡因用于腰丛坐骨神经联合阻滞的临床效果。方法:择期行单侧下肢手术的患者90例,年龄18~65岁,ASAⅠ或Ⅱ级,随机分为3组(n=30):A组给予0.3 ％的罗哌卡因腰丛36 mL、坐骨神经24 mL,B组给予0.36 ％的罗哌卡因腰丛30 mL、坐骨神经24 mL,C组给予0.4％罗哌卡因腰丛27 mL、坐骨神经18 mL。分别于给药后2、5、10、15、20、25、30、35 min测定下肢的感觉、运动评分以及感觉阻滞的时间和运动阻滞的时间。结果:三组患者阻滞起效时间无明显差别,高容量组完全阻滞的持续时间短于低容量组;高容量低浓度组患者完全阻滞率高于低容量组,但达到完全阻滞时间长于低容量组。结论:在剂量相同时罗哌卡因的浓度和容量会影响腰丛和坐骨神经的阻滞效果;高容量罗哌卡因更有利于达到良好的感觉阻滞。

Citation： XU Hongwei,ZHOU Ji,ZHANG Jinfeng,et al. The Clinical Trial of the Same dose Ropivacaine after Lumbar Plexus with Sciatic Nerve Block. West China Medical Journal, 2009, 24(3): 619-621. doi: Copy

1.
2.
3.	TABOADA M,ATANASSOFF PG.Lower extremity nerve block[J].Curr Opin Anaethesiol,2004,17:403-408..
4.	徐仲煌,黄宇光,潘华,等.罗哌卡因用于腰丛－坐骨神经联合阻滞的临床观察[J].中华麻醉学杂志,2002,22:235-238..
5.	DHIR S,GANAPATHY S,LINDSAY P,et al.Case report:ropivacaine neurotoxicity at clinical doses in interscalene brachial plexus block[J].Can J Anaesth,2007,54:912-916..
6.	TABOADA M,ALVAREZ J,CORT?S J,et al.The effects of three different approaches on the onset time of sciatic nerve blocks with 0.75% ropivacaine[J].Anesth Analg,2004,98(1):242-247..
7.	AWAD I T,DUGGAN EM.Posterior lumbar plexus block:anatomy,approaches,and techniques[J].Reg Anesth Pain Med,2005,30:143-149..
8.	CASATI A,FANELLI G,MAGISTRIS L,et al.Minimum local anesthetic volume blocking the femoral nerve in 50% of cases:a doubleblinded comparison between 0.5% ropivacaine and 0.5% bupivacaine[J].Anesth Analg,2001,92(1):205-208..
9.	CASATI A,BACIARELLO M,DI CIANNI S,et al.Effects of ultrasound guidance on the minimum effective anaesthetic volume required to block the femoral nerve[J].Br J Anaesth,2007,98(6):823-827..
10.	ILFELD BM,LOLAND VJ,GERANCHER JC,et al.The effects of varying local anesthetic concentration and volume on continuous popliteal sciatic nerve blocks:a dualcenter,randomized,controlled study[J].Anesth Analg,2008,107(2):701-707..
11.	舒化青,张小洺,姚尚龙等.不同浓度罗哌卡因用于腰丛坐骨神经阻滞的药代动力学[J].中华麻醉学杂志,2006,26:1018-1020..

1.
2.
3. TABOADA M,ATANASSOFF PG.Lower extremity nerve block[J].Curr Opin Anaethesiol,2004,17:403-408..
4. 徐仲煌,黄宇光,潘华,等.罗哌卡因用于腰丛－坐骨神经联合阻滞的临床观察[J].中华麻醉学杂志,2002,22:235-238..
5. DHIR S,GANAPATHY S,LINDSAY P,et al.Case report:ropivacaine neurotoxicity at clinical doses in interscalene brachial plexus block[J].Can J Anaesth,2007,54:912-916..
6. TABOADA M,ALVAREZ J,CORT?S J,et al.The effects of three different approaches on the onset time of sciatic nerve blocks with 0.75% ropivacaine[J].Anesth Analg,2004,98(1):242-247..
7. AWAD I T,DUGGAN EM.Posterior lumbar plexus block:anatomy,approaches,and techniques[J].Reg Anesth Pain Med,2005,30:143-149..
8. CASATI A,FANELLI G,MAGISTRIS L,et al.Minimum local anesthetic volume blocking the femoral nerve in 50% of cases:a doubleblinded comparison between 0.5% ropivacaine and 0.5% bupivacaine[J].Anesth Analg,2001,92(1):205-208..
9. CASATI A,BACIARELLO M,DI CIANNI S,et al.Effects of ultrasound guidance on the minimum effective anaesthetic volume required to block the femoral nerve[J].Br J Anaesth,2007,98(6):823-827..
10. ILFELD BM,LOLAND VJ,GERANCHER JC,et al.The effects of varying local anesthetic concentration and volume on continuous popliteal sciatic nerve blocks:a dualcenter,randomized,controlled study[J].Anesth Analg,2008,107(2):701-707..
11. 舒化青,张小洺,姚尚龙等.不同浓度罗哌卡因用于腰丛坐骨神经阻滞的药代动力学[J].中华麻醉学杂志,2006,26:1018-1020..

West China Medical Journal

The Clinical Trial of the Same dose Ropivacaine after Lumbar Plexus with Sciatic Nerve Block

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