The Research of Bispectral Index Monitor in Ventilated Patients In ICU_West China Medical Journal

Authors：

ZHANG Chuan , LI Xiaojin , ZHENG Bixia , et al.

Department of ICU, the Third People’s Hospital of Chengdu City,Chengdu 610041,China;

Corresponding author：

Keywords：

脑电双频指数; 机械通气; ICU

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目的:探讨ICU机械通气患者使用脑电双频指数(BIS)指导镇静的临床作用。方法:采用前瞻性完全随机对照研究。将53例患者分为2组,分别用BIS和主观评分进行镇静监测48h,设定SAS评分3~4分为镇静目标,评估临床指标如机械通气时间、ICU住院日、给药率和肢体制动率的组间差异,评价BIS监测在机械通气患者的临床应用价值。结果: 两组患者均达镇静目标,BIS监测较常规镇静监测组机械通气时间(1733±1577d vs. 3983±5633d)和ICU住院日(2160±2045d vs. 4167±5581d)缩短,肢体制动率下降(4070%vs.7690%)(P lt;005),但给药率无统计学意义(P gt;005)。结论:BIS监测可以缩短ICU患者的机械通气时间和ＧICU住院日,减少肢体制动率。

Citation： ZHANG Chuan,LI Xiaojin,ZHENG Bixia,et al.. The Research of Bispectral Index Monitor in Ventilated Patients In ICU. West China Medical Journal, 2009, 24(5): 1133-1135. doi: Copy

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2.	LEBLANC J M, DASTA J F, KANEGILL S L, et al. Role of the bispectral index in sedation monitoring in the ICU[J]. AnnPharmacother,2006,40(3):490500.
3.	NASRAWAY SASA J R, WU E C, KELLEHER R M, et al. How reliable is the Bispectral Index in critically ill patients? Aprospective, comparative, single blinded observer study[J]. Crit Care Med,2002,30:14831487.
4.	IBRAHIM A E, TARADAY J K, KHAMSEH E D. Bislmetml index monitoring during sedation with sevoflurane, midazolam, and propofol [J]. Anesthesiology,2001,95(5):11511159.
5.	张川,李孝锦,李晓玉,等. BIS监测在机械通气患者镇静深度评价中的价值[J].华西医学,2008,23(1):4142.
6.	SIMMONS L E, RIKER R R, PRATO B S, et al. Assessing sedation during intensive care unit mechanical ventilation with the Bispectral Index and the SedationAgitation Scale[J]. Crit Care Med,1999,27(8):14991504.

1. JACOBI J, FRASER G L, COURSIN DB, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult [J]. Crit Care Med,2002,30(1):119141.
2. LEBLANC J M, DASTA J F, KANEGILL S L, et al. Role of the bispectral index in sedation monitoring in the ICU[J]. AnnPharmacother,2006,40(3):490500.
3. NASRAWAY SASA J R, WU E C, KELLEHER R M, et al. How reliable is the Bispectral Index in critically ill patients? Aprospective, comparative, single blinded observer study[J]. Crit Care Med,2002,30:14831487.
4. IBRAHIM A E, TARADAY J K, KHAMSEH E D. Bislmetml index monitoring during sedation with sevoflurane, midazolam, and propofol [J]. Anesthesiology,2001,95(5):11511159.
5. 张川,李孝锦,李晓玉,等. BIS监测在机械通气患者镇静深度评价中的价值[J].华西医学,2008,23(1):4142.
6. SIMMONS L E, RIKER R R, PRATO B S, et al. Assessing sedation during intensive care unit mechanical ventilation with the Bispectral Index and the SedationAgitation Scale[J]. Crit Care Med,1999,27(8):14991504.

West China Medical Journal

The Research of Bispectral Index Monitor in Ventilated Patients In ICU

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