Observation of Domestic Gemcitabine Combined Cisplatin in the Second Line of Treatment of Patients with Metastatic Breast Cancer_West China Medical Journal

Authors：

YAN Jun.

Oncology Department of No.1 People’s Hospital of Zigong, Zigong Sichuan 643000, China;

Corresponding author：

Keywords：

乳腺肿瘤; 吉西他滨; 顺铂; 化学治疗

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目的:评价国产吉西他滨(泽菲)联合顺铂二线治疗晚期乳腺癌的疗效和不良反应。方法:34例晚期乳腺癌患者采用国产吉西他滨1000mg/m2,静脉滴注30min,第1、8天;顺铂25mg/m2,静脉滴注,第1～3天。21d为一个周期,至少完成两周期后评价疗效。结果:完全缓解2例(588%),部分缓解16例(4706%),总有效率为5294%。中位疾病进展时间为65月,中位生存期为114月;主要不良反应为骨髓抑制和胃肠道反应,所有不良反应在停药后或对症处理后均可恢复正常。结论:国产吉西他滨联合顺铂二线治疗晚期乳腺癌疗效较好,毒副反应可耐受,值得进一步研究。

Citation： YAN Jun.. Observation of Domestic Gemcitabine Combined Cisplatin in the Second Line of Treatment of Patients with Metastatic Breast Cancer. West China Medical Journal, 2009, 24(5): 1178-1179. doi: Copy

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West China Medical Journal

Observation of Domestic Gemcitabine Combined Cisplatin in the Second Line of Treatment of Patients with Metastatic Breast Cancer

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