目的:了解阻塞性睡眠呼吸暂停综合征患者的心率变异改变。方法:对67例睡眠打鼾患者同步进行24小时动态心电图及多导睡眠图监测。根据PSG检测结果分为OSAS组和单纯鼾症组,比较组间低频峰(LF),高频峰(HF),低频峰与高频峰的比值(LF/HF),正常RR间期平均值及其标准差值(SDNN),正常RR间期差值均方根(rMSSD)。结果:OSAS组中,频域分析指标:LF,HF,均低于单纯鼾症组,LF/HF高于对照组,时域分析指标:SDNN,rMSSD均低于对照组。结论:OSAHS患者心率变异性降低。
Citation：
WANG Yongsheng,LI Kai,LIANG Zongan.. HRV Change in Obstructive Sleep Apnea Syndrome. West China Medical Journal, 2009, 24(6): 1439-1441. doi:
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- 1. 中华医学会呼吸病学分会睡眠呼吸疾病学组. 阻塞性睡眠呼吸暂停低通气综合征诊治指南(草案)[J].中华结核和呼吸杂志, 2002, 25(10):195-198.
- 2. HE J KRYGER MH, ZORICK FJ, et al. Mortality and apnea index in obstructive sleep apnea: experience in 385 male patients[J].Chest., 1988, 94(2):9-14.
- 3. 范洁, 郭兮恒, 黄席珍，等. 阻塞性睡眠呼吸暂停综合征与心率变异及心律失常[J].中华结核和呼吸杂志, 1997, 20(3): 178.
- 4. LF STRAMBI, M ZUCCONI, A OLDANI, et al. Heart rate variability during sleep in snorers with and without obstructive sleep apnea[J]. Chest, 1992, 102(1):1023-1027.
- 5. WIKLUND. Cardiac Rhythm Disturbances and STSegment Depression Episodes in Patients with Obstructive Sleep ApneaHypopnea Syndrome and Its Mechanisms[J]. Chest, 2005, 127(4): 15-22.
- 6. KHOO. Metabolic syndrome and sleep apnoea: all proinflammatory states[J]. Obes Rev, 2007, 8(2): 119-27.
