The Application of 18F-FDG PET/CT in Head and Neck Neoplasms_West China Medical Journal

Authors：

1PET Center; 2the Department of Radiation Oncology, Chengdu Army General Hospital, Chengdu 610083, China;

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Keywords：

PET/CT; 头颈部肿瘤; 放射治疗

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目的:探讨18F-FDG PET/CT在头颈部肿瘤的临床应用价值。方法:58例头颈部恶性肿瘤病例,男37例,女21例,年龄21~78岁。其中:牙龈癌3例,上颌窦癌2例,舌癌2例,腮腺癌1例,鼻咽癌24例,喉癌8例,甲状腺癌4例,原发灶不明的颈部淋巴结转移瘤14例。使用18F-FDG行全身PET/CT扫描,依据PET图像、CT图像和PET/CT融合图像及标准化摄取值(SUV)进行综合评价。结果:29例放疗患者中的11例拟行根治性放疗的患者,有4例改行姑息性放疗,8例重新勾画了放疗靶区及调整了放疗剂量,3例改行其它治疗;15例进行了放疗后的疗效评估;14例原发灶不明的颈部淋巴结转移瘤8例找到了原发灶。结论:PET/CT可以对头颈部恶性肿瘤进行准确的临床分期,精确勾画放疗的生物靶区,准确而快捷地确定肿瘤复发的位置与侵犯范围,在颈部不明原发灶转移瘤的应用中具有简便、快捷、无创和灵敏等临床特点。

Citation： ZHOU Ke,LUO Jianhua,CHEN Zhiming,et al. The Application of 18F-FDG PET/CT in Head and Neck Neoplasms. West China Medical Journal, 2009, 24(6): 1490-1492. doi: Copy

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1. 潘中允.PET/CT诊断学[M].北京:人民卫生出版社,2009:1;615-629.
2. SHODER H, YEUNG H W D, GONEN M, et al. Head and neck cancer: clinical usefulness and accuracy of PET/CT image fusion[J]. Radiology,2004,231:65-72.
3. DIZENDORF E V, BOUMER B G, VON SCHULTHESS G K, et al. Impact of wholebody 18FFDG PET on staging and managing patients for radiation therapy[J]. J Nucl Med,2002,44:24-29.
4. CIERNIK I F, DIZERDORF E, BOUMENT B G, et al. Radiation treatment planning with on integrated position emission and computed tomography (PET/CT): a feasibility study[J]. Int J Radiat Oncol Biol Phys,2003,57:853-863.
5. DIZENDORF E. Impact biologic target volumes in radiation treatment planning[J]. J Nucl Med,2002,(435):A-118.
6. GREVEN K M, WILLIAMS D W, KEYES J W, et al. Distinguishing tumor recurrence from irradiation sequel as with positron emission tomography in patients treated for larynx cancer[J]. Int J Radiat Oncol Biolphys,1994,29:841-845.
7. NARESH K N. Do metastatic tumours from an unknown primary angiugemic incompetence of the tumour at primary site? A hypotheses[J]. Med Hypotheses,2002,3:357.
8. ALBERINI J L， BELHOCINE T, HUSTINX R, et al. Whole body positron emission tomography using fluoride OXY glucose in patients with metastases of unknown tunours (CPU syndrome)[J]. Nucl Med Commun,2003,10:1081.
9. DELGADO BULTON RC, FEMADEZ C, CNORZAL MATE A, et al. Meta analysis of the performance of 18FFDG PET in primary tumor detection in unknow primary tumors[J]. J Nucl Med,2000,5:816.

West China Medical Journal

The Application of 18F-FDG PET/CT in Head and Neck Neoplasms

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