Radiotherapy in Treatment for Advanced Unresectable Hilar Cholangiocarcinoma_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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孟岩 , 周海华

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肝门部胆管癌; 不可手术; 放射治疗

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Citation： 孟岩,周海华. Radiotherapy in Treatment for Advanced Unresectable Hilar Cholangiocarcinoma. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2011, 18(6): 583-584. doi: Copy

1.	Schoenthaler R. Hepatobiliary carcinomas//Steven A, Theodore L. Clinical Radiation Oncology [M ]. Philadelphia: W.B. Saunders Company, 1996: 667675.
2.	朱锦辉, 刘颖斌, 彭淑牖. 影像学检查在肝门部胆管癌诊断中的应用 [J]. 中国实用外科杂志, 2005, 25(5): 313315.
3.	Jarnagin WR, Fong Y, DeMatteo RP, et al. Staging respectability, and outcoming in 225 patients with hilar cholangiocarcinoma [J]. Ann Surg， 2001, 234(4): 507517.
4.	Are C, Gonen M, D’Angelica M, et al. Differential diagnosis of proximal biliary obstruction [J]. Surgery, 2006, 140(5): 756763.
5.	高黎, 冯宁远, 翟仁友, 等. 金属内支架对放射治疗影响的体外研究 [J]. 中华放射学杂志, 2001, 35（1）: 7576.
6.	Cheng JL, Bruno MJ, Bergman JJ, et al. Endoscopic palliation of patients with biliary obstruction caused by nonresectable hilar cholangiocarcinoma: efficacy of selfexpandable metallic wallstents [J]. Gastrointest Endosc, 2002, 56（1）: 3339.
7.	De Palma GD, Pezzullo A, Rega M, et al. Unilateral placement of metallic stents for malignant hilar obstruction: a prospective study [J]. Gastrointest Endosc, 2003, 58（1）: 5053.
8.	Pinol V, Castells A, Bordas JM, et al. Percutaneous selfexpanding metal stents versus endoscopic polyethylene endoprostheses for treating malignant biliary obstuction: randomized chinical trial [J]. Radiology, 2002, 225（1）: 2734.
9.	Shinchi H, Takao S, Nishida H, et al. Length and quality of survival following external beam radiotherapy combined with expandable metallic stent for unresectable hilar cholangiocarcinoma [J]. J Surg Oncol, 2000, 75（2）: 8994.
10.	钱晓军, 戴定可, 翟仁友. 恶性梗阻性黄疸介入治疗的疗效分析 [J]. 中华肝胆外科杂志, 2004, 10（11）: 752755.
11.	Kamada T, Saitou HS, Takaura A, et al. The role of radiotherapy in the management of extrahepatic bile duct cancer: an analysis of 145 consecutive patients treated with intraluminal and/or external beam radiotherapy [J]. Int J Radiat Oncol Biol Phys, 1996, 34（4）: 767774.
12.	Alden ME, Mohiuddin M. The impact of radiation dose in combined external beam and intraluminal Ir192 brachytherapy for bile duct cancer [J]. Int J Radiat Oncol Biol Phys, 1994, 28（4）: 945951.
13.	Ishii H, Furuse J, Nagase M, et al. Relief of jaundice by external beam radiotherapy and intraluminal brachytherapy in patients with extrahepatic cholangiocarcinoma: results without stenting [J]. Hepatogastroenterology, 2004, 51（58）: 954957.
14.	李玉, 王宁, 田起和, 等. 金属支架联合立体定向适形放疗治疗肝门部胆管癌 [J]. 中华放射肿瘤学杂志, 2005, 14（1）: 3941.
15.	Tsujino K, Landry JC, Smith RG, et al. Definitive radiation therapy for extrahepatic bile duct carcinoma [J]. Radiology, 1995, 196（1）: 275280.
16.	郑爱青, 于金明, 徐瑾, 等. 立体定向适形放疗剂量对晚期胆管癌的治疗疗效的影响 [J]. 中国癌症杂志, 2004, 14(4): 339341.
17.	Czito BG, Anscher MS, Willett CG. Radiation therapy in the treatment of cholangiocarcinoma [J]. Oncology (Williston Park), 2006, 20(8): 873884.
18.	Kaido T, Imamura M. Unresectable hilar cholangiocarcinoma completely reduced by external radiation therapy [J]. Hepatogas Troenterology, 2005, 52(63): 725727.
19.	王若雨, 金实, 陈英海, 等. 胆道恶性梗阻腔内放射治疗的入路设置及放射剂量的研究 [J]. 中华普通外科杂志, 2001, 16(2): 8890.
20.	胡立宽, 宋轶鹏. 192 Ir联合X线立体定向放射治疗肝门部胆管癌 [J]. 实用医学杂志, 2001, 17(11): 724726.
21.	杨莉莉, 曹贵文，崔新江，等. 双介入治疗肝门部胆管癌的临床应用研究 [J]. 医学影像学杂志, 2010, 20(2): 270273.

1. Schoenthaler R. Hepatobiliary carcinomas//Steven A, Theodore L. Clinical Radiation Oncology [M ]. Philadelphia: W.B. Saunders Company, 1996: 667675.
2. 朱锦辉, 刘颖斌, 彭淑牖. 影像学检查在肝门部胆管癌诊断中的应用 [J]. 中国实用外科杂志, 2005, 25(5): 313315.
3. Jarnagin WR, Fong Y, DeMatteo RP, et al. Staging respectability, and outcoming in 225 patients with hilar cholangiocarcinoma [J]. Ann Surg， 2001, 234(4): 507517.
4. Are C, Gonen M, D’Angelica M, et al. Differential diagnosis of proximal biliary obstruction [J]. Surgery, 2006, 140(5): 756763.
5. 高黎, 冯宁远, 翟仁友, 等. 金属内支架对放射治疗影响的体外研究 [J]. 中华放射学杂志, 2001, 35（1）: 7576.
6. Cheng JL, Bruno MJ, Bergman JJ, et al. Endoscopic palliation of patients with biliary obstruction caused by nonresectable hilar cholangiocarcinoma: efficacy of selfexpandable metallic wallstents [J]. Gastrointest Endosc, 2002, 56（1）: 3339.
7. De Palma GD, Pezzullo A, Rega M, et al. Unilateral placement of metallic stents for malignant hilar obstruction: a prospective study [J]. Gastrointest Endosc, 2003, 58（1）: 5053.
8. Pinol V, Castells A, Bordas JM, et al. Percutaneous selfexpanding metal stents versus endoscopic polyethylene endoprostheses for treating malignant biliary obstuction: randomized chinical trial [J]. Radiology, 2002, 225（1）: 2734.
9. Shinchi H, Takao S, Nishida H, et al. Length and quality of survival following external beam radiotherapy combined with expandable metallic stent for unresectable hilar cholangiocarcinoma [J]. J Surg Oncol, 2000, 75（2）: 8994.
10. 钱晓军, 戴定可, 翟仁友. 恶性梗阻性黄疸介入治疗的疗效分析 [J]. 中华肝胆外科杂志, 2004, 10（11）: 752755.
11. Kamada T, Saitou HS, Takaura A, et al. The role of radiotherapy in the management of extrahepatic bile duct cancer: an analysis of 145 consecutive patients treated with intraluminal and/or external beam radiotherapy [J]. Int J Radiat Oncol Biol Phys, 1996, 34（4）: 767774.
12. Alden ME, Mohiuddin M. The impact of radiation dose in combined external beam and intraluminal Ir192 brachytherapy for bile duct cancer [J]. Int J Radiat Oncol Biol Phys, 1994, 28（4）: 945951.
13. Ishii H, Furuse J, Nagase M, et al. Relief of jaundice by external beam radiotherapy and intraluminal brachytherapy in patients with extrahepatic cholangiocarcinoma: results without stenting [J]. Hepatogastroenterology, 2004, 51（58）: 954957.
14. 李玉, 王宁, 田起和, 等. 金属支架联合立体定向适形放疗治疗肝门部胆管癌 [J]. 中华放射肿瘤学杂志, 2005, 14（1）: 3941.
15. Tsujino K, Landry JC, Smith RG, et al. Definitive radiation therapy for extrahepatic bile duct carcinoma [J]. Radiology, 1995, 196（1）: 275280.
16. 郑爱青, 于金明, 徐瑾, 等. 立体定向适形放疗剂量对晚期胆管癌的治疗疗效的影响 [J]. 中国癌症杂志, 2004, 14(4): 339341.
17. Czito BG, Anscher MS, Willett CG. Radiation therapy in the treatment of cholangiocarcinoma [J]. Oncology (Williston Park), 2006, 20(8): 873884.
18. Kaido T, Imamura M. Unresectable hilar cholangiocarcinoma completely reduced by external radiation therapy [J]. Hepatogas Troenterology, 2005, 52(63): 725727.
19. 王若雨, 金实, 陈英海, 等. 胆道恶性梗阻腔内放射治疗的入路设置及放射剂量的研究 [J]. 中华普通外科杂志, 2001, 16(2): 8890.
20. 胡立宽, 宋轶鹏. 192 Ir联合X线立体定向放射治疗肝门部胆管癌 [J]. 实用医学杂志, 2001, 17(11): 724726.
21. 杨莉莉, 曹贵文，崔新江，等. 双介入治疗肝门部胆管癌的临床应用研究 [J]. 医学影像学杂志, 2010, 20(2): 270273.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Radiotherapy in Treatment for Advanced Unresectable Hilar Cholangiocarcinoma

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