Pancreatic Lymphoma Misdiagnosed as Pancreatic Carcinoma (Report of 5 Cases )_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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黄中岳 , 费健 , 王建承 , 陈胜 , 吴卫泽 , 韩天权 , 彭承宏 , 张圣道

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Keywords：

胰腺淋巴瘤; 鉴别诊断; 治疗

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目的探讨胰腺淋巴瘤和胰腺癌的鉴别诊断及治疗。
方法回顾性分析我院2000年1月至2008年4月期间经病理确诊的5例胰腺淋巴瘤患者的临床资料。
结果本组5例患者临床症状以腹痛、发热、黄疸为主，除1例外血浆CA19-9均正常，临床表现无法区分胰腺淋巴瘤和胰腺癌，CT等影像学有助于鉴别诊断。胰腺淋巴瘤CT增强扫描后均见强化表现，胰管不粗，和周围大血管关系紧密，邻近血管结构被推移，但无浸润、包绕现象。治疗以化疗为主，除1例失访外，其余4例分别存活24、14、14、13个月。
结论胰腺淋巴瘤是一种罕见的疾病，临床症状缺乏特异性，极易与胰腺癌混淆，治疗和预后却与胰腺癌不尽相同，临床上应该尽量通过CT或超声下穿刺明确诊断，以避免不必要的手术。

Citation： 黄中岳,费健,王建承,陈胜,吴卫泽,韩天权,彭承宏,张圣道. Pancreatic Lymphoma Misdiagnosed as Pancreatic Carcinoma (Report of 5 Cases ). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2009, 16(2): 150-151. doi: Copy

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1. Basu A, Patil N, Mohindra P, et al. Isolated non-Hodgkin’s lymphoma of the pancreas: case report and review of literature [Ｊ]. J Cancer Res Ther, 2007; 3(4)： 236.
2. 胡亚，杜潇，廖泉，等.原发性胰腺淋巴瘤的诊疗分析 [Ｊ].中国普外基础与临床杂志， 2008； 15(4)： 285.
3. Salvatore JR, Cooper B, Shah I, et al. Primary pancreatic lymphoma: a case report, literature review, and proposal for nomenclature [Ｊ]. Med Oncol, 2000; 17(3)： 237.
4. Tuchek JM, De Jong SA, Pickleman J. Diagnosis, surgical intervention and prognosis of primary pancreatic lymphoma [Ｊ]. Am Surg, 1993; 59(8)： 513.
5. Jayanthi V, Randhir J, Rajesh N. Problems in diagnosing lymphoma of the pancreas with computed tomography: A case report [Ｊ]. J Gastrointestin Liver Dis, 2007; 16(1)： 101.
6. Merkle EM, Bender GN, Brambs HJ. Imaging findings in pancreatic lymphoma: differential aspects [Ｊ]. AJR Am J Roentgenol, 2000; 174(3)： 671.
7. Gleeson FC, Zhang L, Levy MJ, et al. Primary pancreatic lymphoma: endoscopic ultrasound-guided Trucut biopsy to the rescue [Ｊ]. Endoscopy, 2008; 40(Suppl 2)： E23.
8. Islam S, Callery MP. Primary pancreatic lymphoma a diagnosis to remember [Ｊ]. Surgery,2001; 129(3)： 380.
9. Lin H, Li SD, Hu XG, et al. Primary pancreatic lymphoma: report of six cases [Ｊ]. World J Gastroenterol， 2006; 12(31)∶5064.
10. 何天霖，胡先贵，刘瑞，等.原发性胰腺淋巴瘤的诊断和治疗（附9例报告）[Ｊ]. 第二军医大学学报， 2005； 26(8)： 875.
11. Grimison PS, Chin MT, Harrison ML, et al. Primary pancreatic lymphoma-pancreatic tumours that are potentially curable without resection, a retrospective review of four cases [Ｊ]. BMC Cancer, 2006; 6(5)： 117.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Pancreatic Lymphoma Misdiagnosed as Pancreatic Carcinoma (Report of 5 Cases )

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