Simultaneous Pancreas-Kidney Transplantation （Report of One Case )_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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田伯乐 , 张肇达 , 刘续宝 , 胡伟明 , 韩方海 , 麦刚 , 赵纪春 , 王莉 , 陆慧敏 , 任燕 , 罗朝志 , 罗传兴 , 袁朝新 , 陆燕蓉

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胰腺,肾,移植

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【摘要】目的报道四川大学华西医院首例胰肾联合移植。方法 2007年3月我院对1例2型糖尿病合并肾功能衰竭患者成功施行了胰肾联合移植手术，将肾脏移植于左侧髂窝，胰腺移植于右侧髂窝，胰腺移植采用肠道-体循环回流术式。结果术后第1 d C-肽升至正常水平，第4 d血肌酐恢复正常，第11 d血尿素氮恢复正常，血糖逐渐趋于稳定，第16 d完全停用胰岛素，术后3周OGTT结果显示移植胰腺功能正常。随访6个月移植胰腺、肾脏功能正常，没有发生手术相关并发症。
结论胰肾联合移植是治疗2型糖尿病合并肾功能衰竭的有效手段。

Citation： 田伯乐,张肇达,刘续宝,胡伟明,韩方海,麦刚,赵纪春,王莉,陆慧敏,任燕,罗朝志,罗传兴,袁朝新,陆燕蓉. Simultaneous Pancreas-Kidney Transplantation （Report of One Case ). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2008, 15(3): 203-204. doi: Copy

1.	9 Ki Wan K, Rick S, Rod M, et al. Simultaneous kidney-pancreas transplantation (SPK) for type 2 diabetes mellitus: Single center experience [Ｊ] . Am J Transplant, 2007; 7 Suppl 2 ∶ 250.
2.	明长生, 甑忠广, 曾凡军, 等. 32例胰肾同期联合移植的近期疗效 [Ｊ].　中华器官移植杂志,　2006; 27(1)∶36.
3.	Troppmann C, Benedetti E, Papalois BE, et al. Impact of vascular reconstruction technique on posttransplant pancreas graft thrombosis incidence after simultaneous pancreas-kidney transplantation [Ｊ].Transplant Proc, 1995; 27(1)∶1331.
4.	Reddy KS, Johnston TD, Karounas D, et al. Hospital charges following simultaneous kidney-pancreas transplantation: enteric drainage versus bladder drainage [Ｊ]. Clin Transplant, 2000; 14(4 Pt 2)∶375.
5.	明长生. 临床胰腺和胰肾联合移植的现状 [Ｊ]. 中华器官移植杂志, 2006; 27（11）∶699.
6.	Schmied BM, Müller SA, Mehrabi A, et al. Immunosuppressive standards in simultaneous kidney-pancreas transplantation [Ｊ].Clin Transplant, 2006; 20 Suppl 17∶44.
7.	黄东胜, 徐骁. 胰肾联合移植的指征和现状 [Ｊ]. 中国普外基础与临床杂志, 2003; 10（6）∶528.
8.	Gruessner AC, Sutherland DE. Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004 [Ｊ]. Clin Transplant, 2005; 19(4)∶433.
9.	Nath DS, Gruessner AC, Kandaswamy R, et al. Outcomes of pancreas transplants for patients with type 2 diabetes mellitus [Ｊ]. Clin Transplant, 2005; 19(6)∶792.

1. 9 Ki Wan K, Rick S, Rod M, et al. Simultaneous kidney-pancreas transplantation (SPK) for type 2 diabetes mellitus: Single center experience [Ｊ] . Am J Transplant, 2007; 7 Suppl 2 ∶ 250.
2. 明长生, 甑忠广, 曾凡军, 等. 32例胰肾同期联合移植的近期疗效 [Ｊ].　中华器官移植杂志,　2006; 27(1)∶36.
3. Troppmann C, Benedetti E, Papalois BE, et al. Impact of vascular reconstruction technique on posttransplant pancreas graft thrombosis incidence after simultaneous pancreas-kidney transplantation [Ｊ].Transplant Proc, 1995; 27(1)∶1331.
4. Reddy KS, Johnston TD, Karounas D, et al. Hospital charges following simultaneous kidney-pancreas transplantation: enteric drainage versus bladder drainage [Ｊ]. Clin Transplant, 2000; 14(4 Pt 2)∶375.
5. 明长生. 临床胰腺和胰肾联合移植的现状 [Ｊ]. 中华器官移植杂志, 2006; 27（11）∶699.
6. Schmied BM, Müller SA, Mehrabi A, et al. Immunosuppressive standards in simultaneous kidney-pancreas transplantation [Ｊ].Clin Transplant, 2006; 20 Suppl 17∶44.
7. 黄东胜, 徐骁. 胰肾联合移植的指征和现状 [Ｊ]. 中国普外基础与临床杂志, 2003; 10（6）∶528.
8. Gruessner AC, Sutherland DE. Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004 [Ｊ]. Clin Transplant, 2005; 19(4)∶433.
9. Nath DS, Gruessner AC, Kandaswamy R, et al. Outcomes of pancreas transplants for patients with type 2 diabetes mellitus [Ｊ]. Clin Transplant, 2005; 19(6)∶792.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Simultaneous Pancreas-Kidney Transplantation （Report of One Case )

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