LIU Gang , SUN Xuejun , REN Hong , SHI Jingsen.
  • Lab of Hepatobiliary Surgery, The First Affiliated Hospital, Medical College of Xi’an Jiaotong University, Xi’an 710061， China;
Gallstone pancreatitis Bacterial culture Antibiotic Microorganism drug sensitivitytest
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【Abstract】ObjectiveTo study the relationship between the bacterial spectrum difference of gallbladder mucosa and choledochus bile and clinical prognosis of gallstone pancreatitis.
MethodsA synchronic bacterial culture and drug sensitivity test were carried out on 48 patients with gallstone pancreatitis.
ResultsThe cases of positive gallbladder mucosa and choledochus bile were 13 (27.1%) and 31 (64.6%) respectively. The cases of double positivity were 12 (25.0%). The cultural strains of gallbladder mucosa and choledochus bile were significantly different. Some strains were only found in choledochus bile，whereas in gallbladder mucosa L-form bacteria predominated.
ConclusionThe most common causative strain of gallstone pancreatitis is Bacterium coli. The drug-resistant strain emerges maybe due to bacterium immigration and delitescence in gallbladder mucosa. L-form bacteria should be considered when using antibiotics, because L-form bacteria have close relationship with the prognosis of gallstone pancreatitis.

Citation： LIU Gang,SUN Xuejun,REN Hong,SHI Jingsen.. Relationship Between the Bacterial Spectrum Difference of Gallbladder Mucosa and Choledochus Bile and Clinical Prognosis of Gallstone Pancreatitis. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2006, 13(4): 386-389. doi: Copy