THE CHANGE OF CELLULAR FACTOR IN PERIOPERATIVE PATIENTS WITH OBSTRUCTIVE JAUNDICE_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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Department of General Surgery, The Second Afffiliated Hospital, Kunming Medical College, Kunming 650101;

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Obstruction jaundice Operation Cellular factor

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Objective To study the change of immunologic function of the patient with obstructive jaundice.
Methods The level of the sIL-2R, TNF-α, IL-6 and IL-8 in 36 cases of obstructive jaundice before and after operation were measured.
Results The level of the sIL-2R, TNF-α, IL-6 and IL-8 in 36 cases of obstructive jaundice before operation was higher than normal control group (Ｐ＜0.01). It decreased after the obstruction was removed, and it was close to normal control on 14th day after operation.
Conclusion The result suggest that relief of jaundice could improve the immunologic function of the patient.

Citation： LI Li,RAN Jianghua,LU Xiaoqing,et al.. THE CHANGE OF CELLULAR FACTOR IN PERIOPERATIVE PATIENTS WITH OBSTRUCTIVE JAUNDICE. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2000, 7(3): 170-171. doi: Copy

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1. 李智华，韩本立，何振平等. 抗类脂A治疗梗阻性黄疸病人血液平的影响〔Ｊ〕. 第三军医大学学报， 1999； 21(4)∶265.
2. 王海泉，薛永寿，张臣烈等. 阻塞性黄疸对机体免疫功能影响的研究〔Ｊ〕. 中华外科杂志， 1993； 31(3)∶148.
3. Laurencea A, Rubin MD, David L, et al. The soluble interleukin2 receptor biology, function and clinical application 〔Ｊ〕. Ann Intern Med, 1990; 113(8)∶619.
4. Bemelmens MHA, Gouma DJ, Greve JW, et al. Cytokines tumor necrosis factor and interleukin6 in experimental biliary obstruction in mice 〔Ｊ〕. Hepatology, 1992; 15(6)∶1132.
5. Roiand CR, Goss AJ, Mangino MF. Autoregulation by eicosanoids of human Kupffer cell secretory products. A study of interleukin1, interleukin6, tumor necrosis factoralpha, transforming growth factorbeta, and nitric oxide 〔Ｊ〕. Ann Surg, 1994; 219(4)∶389.
6. 陆晓青，冉江华，郭群等. 急性胰腺炎病人血清TNFα、IL6、IL8含量变化〔Ｊ〕. 现代临床普通外科， 1999； 4(1)∶26.
7. Gross V, Andreesen R, Leser HG, et al. Interleukin8 and netrophil activation in acute pancreatitis: pathogenetic role of prognostic indicator 〔Ｊ〕? Digestion, 1993; 22(3)∶200.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

THE CHANGE OF CELLULAR FACTOR IN PERIOPERATIVE PATIENTS WITH OBSTRUCTIVE JAUNDICE

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