• Department of General Surgery, First Affiliated Hospital, West China University of Medical Sciences, Chengdu 610041;
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Objective  To investigate expression of p16 protein in breast cancer and its clinical significance.
Methods  Using immunohistochemical techniques (LSAB) the expression of p16 protein in 107 breast carcinomas was examined.
Results  The positive rate of p16 protein expression was 40.19% (43/107). The p16 protein over expression of the cases surviving ≤5 years and surviving ≥10 years were 8.00% and 75.68% respectively.
Conclusion  Expression of p16 protein might play an important role in the prognosis of breast cancer.

Citation: YANG Jingqiao,ZHOU Leilei,ZHAO Junling.. EXPRESSION OF p16 PROTEIN IN BREAST CANCER AND ITS CLINICAL SIGNIFICANCE. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2000, 7(5): 297-298. doi: Copy