Objective To explore whether there is enough clinical evidence to confirm that stereotactic aspiration does more good than harm in patients with cerebral hemorrhage.
Method A systematic review of all relevant clinical studies on stereotactic aspiration in the treatment of cerebral hemorrhage.
Results Eight randomized controlled trials (RCTs) including 757 patients and 17 nonrandomized controlled studies including 1 766 patients, as well as 20 uncontrolled studies including 1 244 patients were identified . All studies reported positive results regarding the effects. However, the quality of the included studies were generally poor. The main problem was that most trials reported them as a RCT, but no description of the method of randomization.
Conclusions Stereotactic aspiration in the treatment of cerebral hemorrhage is promising based on present evidence. However, at present, we can not draw definite conclusion whether the treatment does more good than harm compared with noninvasive medical treatment because of the poor quality of included studies. Therefore, more high quality RCTs are required.
Citation: LI Wei,LIU Ming. Systematic Review of Clinical Evidence: the Efficacy of Stereotactic Aspiration in the Treatment of Cerebral Hemorrhage. Chinese Journal of Evidence-Based Medicine, 2004, 04(1): 42-45. doi: Copy