慢性咳嗽在人群的发生率为3%~40%。导致慢性咳嗽的主要原因是上气道咳嗽综合征(UACS)、哮喘和胃食管反流病(GERD) 。也有学者将UACS简化为鼻炎,体现了以鼻腔和鼻窦炎性疾病为代表的上气道疾病对慢性咳嗽的病因学意义。诊疗非吸烟、未服用血管紧张素转化酶(ACE)抑制剂的慢性咳嗽患者,应首先考虑上述三大类疾病,可以单独或联合存在。由于临床症状可能仅表现为咳嗽,同时,病史中提示性的线索通常有限,都可能增加诊断的难度。
Citation:
ZHANG Luo,WANG Xiaodong,HAN Demin. Nasal diseases and upper airway cough syndrome. Chinese Journal of Respiratory and Critical Care Medicine, 2008, 08(6): 404-407. doi:
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,63(Suppl 86):8-160.
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- 1. Morice AH,Kastelik JA.Cough 1:chronic cough in aduhs.Thorax, 2003,58:901-907.
- 2. Pratter MR.Ove~iew of common caases of chronic COUgh:ACCP evidence—based clinical practice guidelines.Chest,2006,129(1 Supp1):59S-62S.
- 3. Pratter MR.Chronic upper airway COUsh syndrome secondary to rhino— sinus diseases(previously referred to as postnasal drip syndrome): ACCP evidence—based clinical practice guidelines.Chest,2006,129 (1 Supp1):63S-71 S.
- 4. 张罗,韩德民,王琪.鼻炎概述.中国耳鼻咽喉头颈外科,2007, 14:19-24.
- 5. 韩德民,张罗,黄丹,等.我国l1城市变应性鼻炎自报患病率调查.中华耳鼻咽喉头颈外科杂志,2007,42:83-89.
- 6. Bousquet J,Khahaev N,Cruz AA,et al.Allergic Rhinitis and its Impact on A~hma(ARIA)2008 update(in collaboration with the rId Health Organization,GA(2)LEN and AllerGen).Allergy.
- 7. 张罗,韩德民.解读2008年新版变应性鼻炎及其对哮喘的影响.中华耳鼻咽喉头颈外科杂志,2008,43:552-557..
- 8. ,63(Suppl 86):8-160.