多发性肌炎/皮肌炎相关的间质性肺疾病急性加重的研究进展_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

郝秀 , 李振华

Corresponding author：

Keywords：

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

结缔组织病相关的间质性肺疾病的死亡率高, 在美国每年约有1600 人死于结缔组织病相关的间质性肺疾病, 约占所有间质性肺疾病死亡人数的25% [ 1] , 死因多为间质性肺疾病的急性加重, 而多发性肌炎/皮肌炎( polymyositis/ dermatomyositis, PM/DM) 是结缔组织病中合并肺间质疾病发病率较高的类型, 且最容易发生间质性肺疾病的急性加重[ 2] 。PM/DM可分为多发性肌炎、典型的皮肌炎、无肌病性皮肌炎( CADM) 。间质性肺疾病可发生于多发性肌炎/ 皮肌炎之前、之中或之后, 且无肌病性皮肌炎的表现无特异性, 故多发性肌炎/ 皮肌炎相关的间质性肺疾病( PM/DM-ILD) 急性加重病死率极高[ 3] 。本文将对PM/DM-ILD 急性加重的相关进展进行综述。

Citation： 郝秀,李振华. 多发性肌炎/皮肌炎相关的间质性肺疾病急性加重的研究进展. Chinese Journal of Respiratory and Critical Care Medicine, 2009, 09(5): 509-511. doi: Copy

1.	冯瑞娥, 刘鸿瑞. 结缔组织疾病相关的肺间质性疾病. 见: 中华医学会第二届全国弥漫性间质性肺病及风湿免疫性疾病肺损伤学术会议论文汇编. 桂林.
2.	张恒, 董怡, 张奉春. 结缔组织病肺间质病变的临床特点分析. 中华风湿病杂志, 1999, 3: 247-248.
3.	Marie I, Hachulla E, Ch　rin P, et al. Interstitial lung disease in polymyositis and dermatomyositis. Arthritis and rheumatism, 2002 , 47: 614-622.
4.	Fathi M, Lundberg IE. Interstitial lung disease in polymyositis and dermatomyositis. Curr Opin Rheumatol, 2005, 17: 701-706.
5.	Ye S, Chen XX, Lu XY, et al. Adult clinically amyopathic dermatomyositis with rapid progressive interstitial lung disease: a retrospective cohort study. Clin Rheumato, 2007, 26: 1647-1654.
6.	Fathi M, Dastmalchi M, Rasmussen E, et al. Interstitial lung disease, a common manifestation of newly diagnosed polymyositis and dermatomyositis. Ann Rheum Dis, 2004, 63: 297-301.
7.	Parambil JG, Myer JL, Ryu JH. Diffuse alveolar damage: uncommon manifestation of pulmonary involvement in patients with connective tissue diseases. Chest, 2006, 130: 553-558.
8.	Kameda H, Nagasawa H, Oqawa H, et al. Combination therapy with corticosteroids, cyclosporine A, and intravenous pulse cyclophosphamide for acute/ subacute interstitial pneumonia in patients with dermatomyositis. J Rheumatol, 2005, 32: 1719-1726.
9.	Hayashi S, Tanaka M, Kobayashi H, et al. High-resolution computed tomography characterization of interstitial lung diseases in polymyositis / dermatomyositis. J Rheumatol, 2008 , 35: 260 -269.
10.	Hideto K, Tsutomu T. Recent advances in the treatment of interstitial lung disease in patients with polymyositis / dermatomyositis. Endocr metab immune disord drug targets, 2006 , 6: 409-415.
11.	Collard HR, Moore BB, Flaherty KR, et al. Acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care, 2007, 176: 636-643.
12.	侯岩峰, 张源潮. 皮肌炎并发肺间质病变. 中国实用内科杂志, 2005, 25: 558.
13.	Mastaglia FL. Inflammatory muscle diseases. Neurol India, 2008 , 56: 263-270.
14.	Southeimer RD, Miyagawa S. Potentially fatal interstitial lung disease can occur in clinically amyopathic dermatomyositis. J Am Acad Dermatol, 2003, 48: 797-798.
15.	田欣伦, 许文兵, 施举红, 等. 普通型间质性肺炎与非特异性间质性肺炎急性加重的临床与病理表现. 中华结核和呼吸杂志, 2008, 31: 255-259.
16.	佟胜全, 史旭华, 苏金梅, 等. 多发性肌炎/ 皮肌炎合并纵隔气肿的临床分析. 中华医学杂志, 2006, 86: 624-627.
17.	Fujita J, Ohtsuki Y, Yoshinouchi T, et al. Idiopathic non-specific interstitial pneumonia: as an “autoimmune interstitial pneumonia”. Respir Med, 2005, 99: 234-240.
18.	Sato T, Fujita J, Yamadori I, et al. Non-specific interstitial pneumonia; as the first clinical presentation of various collagen vascular disorders. Rheumatol Int, 2006, 26: 551-555.
19.	Bohan A, Peter JB. Polymyositis and dermatomyositis. N Engl J Med, 1985, 292: 403-407.
20.	Takada K, Nagasaka K, Miyasaka N. Polymyositis/ dermatomyositis and interstitial lung disease: a new therapeutic approach with T-cellspecific immunosuppressants. Autoimmunity, 2005 , 38: 383 -392.
21.	Saito E, Koike T, Hashimoto H, et al. Efficacy of high-dose intravenous immunoglobulin therapy in Japanese patients with steroid-resistant polymyositis and dermatomyositis . Mod Rheumatol, 2008, 18: 34-44.
22.	Danieli MG, Calcabrini L, Marchetti A, et al. Intravenous immunoglobulin treatment autoimmune diseases. Recenti Prog Med, 2007, 98: 322-326.
23.	Kotani T, Makino S, Takeuchi T, et al. Early intervention with corticosteroids and cyclosporine A and 2-hour postdose blood concentration monitoring improves the prognosis of acute/ subacute interstitial pneumonia in dermatomyositis. J Rheumatol, 2008, 35 : 254-259.
24.	Falagas ME, Manta KG, Betsi GI, et al. Infection-related morbidity and mortality in patients with connective tissue diseases: a systematic review. Clin Rheumatol, 2007 , 26: 663 -670.
25.	, 24-25.

1. 冯瑞娥, 刘鸿瑞. 结缔组织疾病相关的肺间质性疾病. 见: 中华医学会第二届全国弥漫性间质性肺病及风湿免疫性疾病肺损伤学术会议论文汇编. 桂林.
2. 张恒, 董怡, 张奉春. 结缔组织病肺间质病变的临床特点分析. 中华风湿病杂志, 1999, 3: 247-248.
3. Marie I, Hachulla E, Ch　rin P, et al. Interstitial lung disease in polymyositis and dermatomyositis. Arthritis and rheumatism, 2002 , 47: 614-622.
4. Fathi M, Lundberg IE. Interstitial lung disease in polymyositis and dermatomyositis. Curr Opin Rheumatol, 2005, 17: 701-706.
5. Ye S, Chen XX, Lu XY, et al. Adult clinically amyopathic dermatomyositis with rapid progressive interstitial lung disease: a retrospective cohort study. Clin Rheumato, 2007, 26: 1647-1654.
6. Fathi M, Dastmalchi M, Rasmussen E, et al. Interstitial lung disease, a common manifestation of newly diagnosed polymyositis and dermatomyositis. Ann Rheum Dis, 2004, 63: 297-301.
7. Parambil JG, Myer JL, Ryu JH. Diffuse alveolar damage: uncommon manifestation of pulmonary involvement in patients with connective tissue diseases. Chest, 2006, 130: 553-558.
8. Kameda H, Nagasawa H, Oqawa H, et al. Combination therapy with corticosteroids, cyclosporine A, and intravenous pulse cyclophosphamide for acute/ subacute interstitial pneumonia in patients with dermatomyositis. J Rheumatol, 2005, 32: 1719-1726.
9. Hayashi S, Tanaka M, Kobayashi H, et al. High-resolution computed tomography characterization of interstitial lung diseases in polymyositis / dermatomyositis. J Rheumatol, 2008 , 35: 260 -269.
10. Hideto K, Tsutomu T. Recent advances in the treatment of interstitial lung disease in patients with polymyositis / dermatomyositis. Endocr metab immune disord drug targets, 2006 , 6: 409-415.
11. Collard HR, Moore BB, Flaherty KR, et al. Acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care, 2007, 176: 636-643.
12. 侯岩峰, 张源潮. 皮肌炎并发肺间质病变. 中国实用内科杂志, 2005, 25: 558.
13. Mastaglia FL. Inflammatory muscle diseases. Neurol India, 2008 , 56: 263-270.
14. Southeimer RD, Miyagawa S. Potentially fatal interstitial lung disease can occur in clinically amyopathic dermatomyositis. J Am Acad Dermatol, 2003, 48: 797-798.
15. 田欣伦, 许文兵, 施举红, 等. 普通型间质性肺炎与非特异性间质性肺炎急性加重的临床与病理表现. 中华结核和呼吸杂志, 2008, 31: 255-259.
16. 佟胜全, 史旭华, 苏金梅, 等. 多发性肌炎/ 皮肌炎合并纵隔气肿的临床分析. 中华医学杂志, 2006, 86: 624-627.
17. Fujita J, Ohtsuki Y, Yoshinouchi T, et al. Idiopathic non-specific interstitial pneumonia: as an “autoimmune interstitial pneumonia”. Respir Med, 2005, 99: 234-240.
18. Sato T, Fujita J, Yamadori I, et al. Non-specific interstitial pneumonia; as the first clinical presentation of various collagen vascular disorders. Rheumatol Int, 2006, 26: 551-555.
19. Bohan A, Peter JB. Polymyositis and dermatomyositis. N Engl J Med, 1985, 292: 403-407.
20. Takada K, Nagasaka K, Miyasaka N. Polymyositis/ dermatomyositis and interstitial lung disease: a new therapeutic approach with T-cellspecific immunosuppressants. Autoimmunity, 2005 , 38: 383 -392.
21. Saito E, Koike T, Hashimoto H, et al. Efficacy of high-dose intravenous immunoglobulin therapy in Japanese patients with steroid-resistant polymyositis and dermatomyositis . Mod Rheumatol, 2008, 18: 34-44.
22. Danieli MG, Calcabrini L, Marchetti A, et al. Intravenous immunoglobulin treatment autoimmune diseases. Recenti Prog Med, 2007, 98: 322-326.
23. Kotani T, Makino S, Takeuchi T, et al. Early intervention with corticosteroids and cyclosporine A and 2-hour postdose blood concentration monitoring improves the prognosis of acute/ subacute interstitial pneumonia in dermatomyositis. J Rheumatol, 2008, 35 : 254-259.
24. Falagas ME, Manta KG, Betsi GI, et al. Infection-related morbidity and mortality in patients with connective tissue diseases: a systematic review. Clin Rheumatol, 2007 , 26: 663 -670.
25. , 24-25.

Chinese Journal of Respiratory and Critical Care Medicine

多发性肌炎/皮肌炎相关的间质性肺疾病急性加重的研究进展

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content