目的探讨胸中上段食管癌淋巴结清扫的合理范围。 方法回顾性分析2010年1月至2013年10月我院134例胸中上段食管癌淋巴结清扫患者的临床资料。将患者分为两组：三野组，56例，男50例、女6例，年龄（55.4±9.6）岁，行三野淋巴结清扫根治术；二野组，78例，男69例、女9例，年龄（56.3±7.3）岁，行完全二野淋巴结清扫根治术。比较两组临床效果。 结果三野组患者淋巴结转移率明显高于二野组（60.7%vs.42.3%，P < 0.05），主要差别在于三野组有较高的颈部淋巴结转移率（21.4%）。三野组与二野组患者上纵隔淋巴结转移率分别为33.9%和30.8%，差异无统计学意义（P>0.05）。三野组及二野组患者术后并发症发生率差异无统计学意义（P>0.05）。三野组及二野组患者术后１年生存率分别为96.3%和85.5%，差异有统计学意义（P < 0.05）；三野组及二野组患者术后1年内颈部淋巴结复发率分别为1.9%和11.8%，差异有统计学意义（P < 0.05）。 结论三野淋巴结清扫根治术有助于提高胸中上段食管癌手术根治性，能减少术后局部复发和转移，提高患者术后生存率，相对于完全二野淋巴结清扫术并不显著增加手术并发症。
Objective To explore the safety of minimally invasive esophagectomy (MIE) with three-field lymphadenectomy (3-FL) for esophageal squamous cell carcinoma (ESCC) by comparing the short-term outcomes between the 3-FL and the two-field lymphadenectomy (2-FL) in MIE. Methods The clinical data of patients with ESCC who underwent minimally invasive McKeown esophagectomy in our hospital from July 2015 to March 2022 were collected retrospectively. Patients were divided into a 3-FL group and a 2-FL group according to lymph node dissection method. And the clinical outcomes and postoperative complications were compared between the two groups. Results A total of 257 patients with ESCC were included in this study. There were 211 males and 46 females with an average age of 62.2±8.1 years. There were 109 patients in the 3-FL group and 148 patients in the 2-FL group. The operation time of the 3-FL group was about 20 minutes longer than that of the 2-FL group (P<0.001). There was no statistical difference between the two groups in the intraoperatve blood loss (P=0.376). More lymph nodes (P<0.001) and also more positive lymph nodes (P=0.003) were obtained in the 3-FL group than in the 2-FL group, and there was a statistical difference in the pathological N stage between the two groups (P<0.001). But there was no statistical difference in the incidence of anastomotic leak (P=0.667), chyle leak (P=0.421), recurrent laryngeal nerve injury (P=0.081), pulmonary complications (P=0.601), pneumonia (P=0.061), cardiac complications (P=0.383), overall complications (P=0.147) or Clavien-Dindo grading (P=0.152) between the two groups. Conclusion MIE 3-FL can improve the efficiency of lymph node dissection and the accuracy of tumor lymph node staging, but it does not increase the postoperative complications, which is worthy of clinical application.