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find Author "何学志" 11 results
  • 起搏器植入术后4年并发感染性心内膜炎一例

    Release date:2016-08-30 06:06 Export PDF Favorites Scan
  • 原发性左心房恶性肿瘤三例

    Release date:2016-08-30 06:08 Export PDF Favorites Scan
  • 食管、贲门癌全胃切除空肠代食管术后反复出血内镜治疗成功一例

    Release date:2016-08-30 06:08 Export PDF Favorites Scan
  • 腔内带膜支架植入加动脉旁路移植治疗胸主动脉夹层一例

    Release date:2016-08-30 06:22 Export PDF Favorites Scan
  • 高龄巨大左心房粘液瘤一例

    Release date:2016-08-30 06:24 Export PDF Favorites Scan
  • 心脏创伤的救治体会

    Release date:2016-08-30 06:26 Export PDF Favorites Scan
  • 迟发性心包填塞的诊断及治疗

    Release date:2016-08-30 06:28 Export PDF Favorites Scan
  • 右侧开胸小切口清除多次心脏术后感染性心内膜炎赘生物一例

    Release date:2016-08-30 05:46 Export PDF Favorites Scan
  • Local Application of Paclitaxel for Prevention Restenosis of Vein Graft in Rabbits

    Abstract: Objective To investigate the effect of keeping implanted vein graft from restenosis by local application of paclitaxel. Methods Ninetysix New Zealand rabbits were randomly divided into three groups, control group (n=32), group Ⅰ(n=32), group Ⅱ(n=32). The vein graft stenosis model was made in all rabbits. In group Ⅰand group Ⅱ, 1μg and 8μg of paclitaxel was applied locally in pluronic gelatin respectively. There were no local treatment in control group. Grafts were harvested at 1, 2, 4, and 6 weeks and underwent morphological analysis as well as immunohistochemical analysis. Results The intimal thickness in group Ⅱ were significantly decreased compared to those in control group at 1,2,4, and 6 weeks after operation (30.10±4.50μm vs. 48.20±9.16μm, 40.70±6.91μm vs. 54.20±8.67μm, 54.70±7.11μm vs. 68.60±13.72μm, and 68.70±8.24μm vs. 76.40±12.98μm, Plt;0.05). The CD8 positive cells and metallothionein positive cells in group Ⅰand group Ⅱ were significantly decreased compared to those in control group (Plt;0.05). Conclusion The results suggest that perivascular application of paclitaxel inhibits neointimal hyperplasia of vein grafts in a rabbit model, and paclitaxel may have a therapeutic potential for the treatment of vein graft disease.

    Release date:2016-08-30 06:08 Export PDF Favorites Scan
  • Predictive value of myocardial perfusion in the prognosis after coronary artery bypass grafting

    ObjectiveTo evaluate the value of myocardial perfusion change before and after coronary artery bypass grafting (CABG) in predicting postoperative major adverse cardiovascular events (MACE).MethodsA total of 70 CABG patients who received CABG completed by the same operator from January to November 2017 were selected, including 45 males and 25 females with an average age of 64.83±9.09 years. The patients were divided into two groups according to whether the patients had MACE after 1 year of the surgery, including a non-MACE group (group A, n=60) and a MACE group (group B, n=10). The clinical data of patients were compared.ResultsThere were statistical difference in the myocardial contrast echocardiography (MCE) score in the group A before and after surgery (P<0.05), and there were statistically significant differences in the left ventricular size and left ventricular ejection fraction (LVEF) value before and 1 year after surgery (P<0.001), but no statistically significant difference in the size of left atrium (P=0.075). There was no significant difference in the preoperative and postoperative MCE score, and preoperative and postoperative 1-year cardiac ultrasound score in the group B (P>0.05).ConclusionThe change of myocardial perfusion after CABG surgery is associated with postoperative MACE. The evaluation of myocardial perfusion before and after CABG surgery is of great significance for the prognosis evaluation of patients.

    Release date:2020-12-31 03:27 Export PDF Favorites Scan
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