Objective To review the regulation and mechanism of the microRNAs (miRNAs) in the bone and cartilage tissue. Methods Recent l iterature concerning the regulation and mechanism of the miRNAs in the bone and cartilage tissue was extensively reviewed, summarized, and analyzed. Results Recently miRNAs is a hot topic in the bone and cartilage tissue. More and more materials show its important regulatory role in osteogenesis and cartilage growth andregeneration, but the definite mechanisms have not been clear yet. Conclusion The study on miRNAs of bone and cartilage tissue can provide a new access to understanding the degenerative osteoarthritic diseases.
Objective To review the up-to-date development of overseas cl inical study on exercise therapy for patients with knee osteoarthritis. Methods The cl inical researches of exercise therapy for knee osteoarthritis were summarized by reviewing l iterature concerned in recent years. Results Exercise therapy was extensively used in the treatment of knee osteoarthritis not only in hospital but also in community rehabil itation abroad. The main patterns of exercise therapy included muscle strengthening exercise, aerobic exercise and underwater exercise. It was capable of effectively improving patient’s independent l iving abil ity and l ive qual ity, and postproning the time of surgical intervention. But the long-term efficacy of exercise therapy was still under debate. Conclusion Exercise therapy is an effect method to treat knee osteoarthritis.
By reviewing and analyzing the domestic and international rehabilitation medicine education, we try to forecast the development of rehabilitation medicine of Sichuan, and moreover, to summarize and analyze the problems and difficulties of rehabilitation medicine education in this province. Then, we put forward the development countermeasures of Sichuan rehabilitation medicine education from the aspect of talent training object and mode, in order to gradually establish and improve a rehabilitation medicine education system that can adapt to the training requirements of modern medicine, to cultivate talents of rehabilitation medicine suitable for national construction needs at every level, and to improve the overall quality of Sichuan rehabilitation medicine education and build a medical rehabilitation highland in West China.
Objective To analyze the rehabilitation needs and characteristics of patients injured in Jiuzhaigou earthquake, and provide early rehabilitation guidance for the wounded. Methods A total of 42 patients injured in " 8·8” Jiuzhaigou earthquake who were admitted to West China Hospital from August 9th to 16th 2017 for treatment were recruited in this study. Early survey and evaluation were conducted among them by using a self-made questionnaire. Results The top 2 common causes of injury were falling (23 cases, 54.8%) and flying stone (16 cases, 38.1%). The top 2 common injury sites were lower extremity (18 cases, 42.9%) and head (10 cases, 23.8%). Twenty-two cases (52.4%) left the hospital after treatment, 6 (14.3%) went to the Department of Orthopedics, and 6 (14.3%) went to the Department of Neurosurgery. The functional limitations included sensory function in 42 cases (100.0%), mental function in 28 (66.7%), motor function restriction in 24 (57.1%), balance physical limitation in 22 (52.4%), respiratory function in 5 (11.9%), and cardiac function in 1 (2.4%). A total of 37 cases (88.1%) had restricted activities of daily living capacities, mainly including 24 (57.1%) in stair climbing, 24 (57.1%) in walking and 22 (52.4%) in bathing. All the 42 cases needed functional evaluation: 22 (52.4%) needed rehabilitation treatment, and 19 (45.3%) needed rehabilitation aids. Conclusions The injury and function limitation of Jiuzhaigou earthquake victims has its own characteristics. According to the limitation of function, the direction of rehabilitation plan after the earthquake focuses on structural function, psychological function, daily activities and function rehabilitation, so as to bring patients back to the family and society as early as possible.
With the acceleration of the aging in the world and our society, osteoarthritis has become a health concern for patients and health workers. At present, its treatment mainly relies on drug treatment, surgical treatment and rehabilitation. As a safe, non-invasive and simple treatment, pulsed electromagnetic field (PEMF) therapy has been used in clinical treatment of osteoporosis, promoting fracture healing and improving symptoms of osteoarthritis. However, the mechanism of PEMF in the treatment of knee osteoarthritis is still unclear. This paper reviews the effects of PEMF on apoptosis, cytokines, cartilage and subchondral bone in knee osteoarthritis in animal experiments, and the changes of chondrocyte morphology and extracellular matrix in cell experiments, aiming to enable medical workers to better understand the status and development of PEMF in the treatment of knee osteoarthritis in basic experimental researches.