目的 探讨老年人自发性乙状结肠穿孔的病因、诊断及治疗方法。方法 对四川大学华西医院胃肠外科中心2009～2011年期间收治的9例自发性乙状结肠穿孔老年患者的临床资料进行回顾性分析。结果 9例患者中7例有长期便秘史，术前均诊断为“全腹膜炎、腹腔脏器穿孔”而行急诊手术。术中见穿孔位于直乙交界处6例，乙状结肠中上段3例，均在系膜对侧缘。3例行病变处肠段切除加远端封闭、近端造瘘术（Hartmann术），4例行乙状结肠部分切除吻合、横结肠双腔造瘘术，1例行穿孔修补术，1例行穿孔修补加横结肠造瘘术。8例患者治愈出院，1例患者因经济原因放弃治疗。结论 老年人自发性乙状结肠穿孔临床上较少见，其发病与解剖学因素、病理学因素密切相关，便秘等是其重要诱因。及时手术、选择适宜的手术方式以及彻底清除腹腔污染是治疗成功与否的关键。
ObjectiveTo explore the application of MDT mode in the diagnosis and treatment of a large retroperitoneal small cell carcinoma.MethodsA huge retroperitoneal tumor about 25 cm×18 cm was found by the preoperative abdominal MRI examination, which was considered as the malignant tumor. Considering the patient’s condition, MDT consultation of the specialists in radiology, oncology, vascular surgery, urinary surgery, and anesthesiology was conducted.ResultsBy MDT discussion, the general condition of patient was good. At present, the diagnosis of the huge retroperitoneal tumor was confirmed. Although the tumor was surrounded with related organs closely, yet the radical operation was finished smoothly and the R0 resection was achieved through the collaboration of MDT. The operation lasted 365 minutes, and the intraoperative blood loss was about 200 mL. Postoperative pathology confirmed that the tumor margin was negative and no postoperative complication occurred. The total number of hospital stays was 23 days. The patient’s return to the hospital for review in 4 months after discharge revealed a tumor recurrence. Then, combined with radiotherapy and chemotherapy, the patient’s condition was stable during treatment.ConclusionFor rare cases of retroperitoneal small cell carcinoma involving multiple disciplines, the treatment based on MDT is able to bring better clinical outcome to patients due to safer and more feasible.