目的:总结腹腔镜下一期FowlerStephens手术治疗小儿腹腔型隐睾的经验。方法:回顾从2003年3月至2009年3月本组用腹腔镜下一期FowlerStephens手术治疗的腹腔型隐睾13例,共20侧,年龄11月～14岁(平均51岁)。结果:13例患儿中双侧腹腔内高位隐睾7例,一侧腹腔内高位隐睾对侧睾丸萎缩4例(1例一侧为索状性腺),单侧腹腔内高位隐睾2例,共20侧腹腔内高位隐睾行了腹腔镜下一期FowlerStephens手术,同时对萎缩睾丸进行了切除。全组病例没有并发症发生,术后随访3月,下降固定的睾丸均血运良好,无睾丸萎缩发生。结论:腹腔镜治疗腹腔型隐睾的优势十分明显,腹腔型睾丸根据术中判断睾丸的游离程度及精索的松弛情况和睾丸位置,可采用一期FowlerStephens手术和精索松解、睾丸下降固定术,腹腔镜下FowlerStephens手术后的睾丸萎缩发生率明显低于开放FowlerStephens手术。
目的:探讨黄芪颗粒对紫癜性肾炎的临床疗效,为本病的后续治疗提供更多的药物选择。方法:对我院2003年至2008年收治的51例紫癜性肾炎患儿进行出院后的后续治疗并作随访对照观察。对照组根据病情酌情使用双嘧达莫、泼尼松、中药及对症等。治疗组加服黄芪颗粒,6个月～3岁:每次1/2袋,3～6岁每次2/3袋,6～13岁每次1袋,一天两次,疗程2～3个月。结果:治疗组尿常规异常2例(2/26),对照组8例(8/25),差异有统计学意义(χ2=478,Plt;005);治疗组肾炎复发1例(1/26),对照组5例(5/25),差异有统计学意义(χ2=1543,Plt;001)。结论:黄芪颗粒在紫癜性肾炎后续治疗中有肾脏保护作用,可以明显减少尿常规异常和肾炎复发。
Objective To observe the changes of amplitude and latency of mini visual evoked optential (mini VEP) examinations in infants at different age.Methods A total of 84 healthy infants and adults (168 eyes) were randomly selected to underwent mini VEP. According to the age, all the individuals were divided into seven groups: A, 0-3 months; B, 4-6 months; C: 7-12 months; D: 1-3 years; E: 4-6 years; F: 7-12 years; G: adults (control). There were 12 individuals (24 eyes) in each group. By using the stimulater of mini VEP, the flash VEP was performed and the changes of amplitude and latency of P100 wave were recorded and analyzed.Results The average value of amplitude in group A was（7.39plusmn;1.79）mu;V which was the lowest, and the average latency was （137.45plusmn;7.64）ms which was the largest.At the same time, the average amplitude of P100 increased from group A to E (F=359.56); the average latency decreased from Group A to D（F=326.64）; the difference was significant (P＜0.01). The amplitude in group E, F, and G was high and no significant difference was found (F=2.39，P＞0.05);the latency in group D,E,F,and G was short with no significant difference (F=2.64，P＞0.05）.Conclusions With the growth of the infants' age, the amplitude of miniVEP increases and latency decreases; moreover, the latency reaches the normal adult level in advance of the amplitude of miniVEP.
【摘要】 目的 观察急性淋巴细胞白血病（ALL）患儿血清铁蛋白（SF）及β2-微球蛋白（β2-MG）水平变化，探讨SF和β2-MG水平变化对ALL患儿临床治疗效果的应用价值。 方法 对2008年7月-2010年4月期间血液病区住院确诊为ALL的患儿53例，病情得到控制缓解后的ALL患儿28例，分别抽取空腹静脉血进行SF和β2-MG测定，并选取正常健康儿童30例作为对照组。 结果 ALL患儿治疗前血清SF和β2-MG水平均高于正常对照组（Plt;0.01），经治疗缓解后ALL患儿的SF和β2-MG水平显著降低，并随着病情的转归而逐渐恢复至正常水平；与治疗前比较，差异有统计学意义（Plt;0.01）。 结论 SF和β2-MG可作为ALL临床治疗效果的有效监测指标。【Abstract】 Objective To observe the dynamic changes of Serum Ferritin(SF) and β2-MG levels in children with acute lymphoblastic leukemia(ALL) and to investigate its clinical significance on clinical curative effect. Methods Fifty-three in-patients with ALL, 28 relieved patients from July 2008 to April 2010 in our Hematology and 30 normal as control were selected in our study. The venousblood of patients and controls were extract in order to detect SF and β2-MG. Results Before the treatment, the level of SF and β2-MG in ALL group were significantly higher than those in the control group (Plt;0.01). After the treatment, the level of SF and β2-MG in ALL group decreased significantly (Plt;0.01), and they return to normal level gradually with the outcome; compared with before the treatment, the differences were statistically significant(Plt;0.01). Conclusion SF and β2-MG can be used as a helpful indicator to evaluate the therapeutic effect of ALL.