ObjectiveTo investigate the value of postoperative CT examination for evaluation of local complications in patients with low rectal carcinoma after total mesorectal excision with anal sphincter preservation. MethodsThe patients with low rectal carcinoma who received total mesorectal excision (TME) with anal sphincter preservation were examined using contrastenhanced CT in one year period from May 2009 to May 2010. Particular attention was paid to the presence of anastomotic leakage, local recurrence and status of lymph nodes. ResultsTotal of 82 patients (52 men, 30 women; mean age 57.8 years old; range 25.74 years old) were included in the study. Over a mean 10-month follow-up, 8 cases (9.8%) had clinically or surgically confirmed anastomotic leak, 6 cases (7.3%) had local recurrence around the anastomotic site, and 4 cases (4.9%) showed pelvic and distant metastatic lymphadenopathy. ConclusionPostoperative CT examination, including baseline and follow-up CT studies, is very useful for diagnosing anastomotic leakage, local tumor recurrence and lymphadenopathy.
ObjectiveTo investigate the effect of pelvic autonomic nerve preservation (PANP) with total mesorectal excision (TME) on sexual and urinary function in male rectal cancer patients. MethodsClinical data of eightyfour patients with rectal cancer from January 2008 to October 2010 in our hospital were analyzed. According to different operative techniques, all the patients were divided into two groups: PANP+TME group (n=41) and TME group (n=43). The sexual dysfunction, urination disorder rate, and local recurrence rate after operation of patients between two groups were compared. ResultsErectile dysfunction rate of patients in TME+PANP group and TME group was 29.3% (12/41) and 76.7% (33/43), ejaculation disorder rate was 26.8% (11/41) and 79.1% (34/43), and urination dysfunction rate was 24.4% (10/41) and 79.1% (34/43), respectively. The rate of sexual and urinary dysfunction of patients in TME+PANP group was significantly lower than that in TME group (Plt;0.05). Local recurrence rate of patients in TME+PANP group (9.8%, 4/41) was similar to that in TME group (11.6%, 5/43), Pgt;0.05. ConclusionPANP based on TME can reduce effectively the rate of sexual and urinary dysfunction in male rectal cancer patients, which does not increase the local recurrence rate after operation.
目的 探讨中低位直肠癌经全系膜切除(TME)并双吻合器吻合术后吻合口的局部效果。方法 选取我院2004年3月至2008年6月期间收治的142例行TME并双吻合器吻合术的中低位直肠癌患者的临床资料进行回顾性分析。结果 所有病例手术操作均顺利,术中无死亡。术后无吻合口漏等严重并发症发生。吻合口狭窄发生率为6.3%(9/142)。术后24个月时局部复发率为7.6%(8/105)。结论 在中低位直肠癌治疗中只要合理选择病例、严格规范术中操作、术后积极观察处理,TME并双吻合器吻合术可以有效降低吻合口并发症的发生。
目的 探讨国产单吻合器在低位直肠癌保肛手术中的临床应用效果。方法 结合相关文献回顾性分析2003年1月至2007年12月期间我院收治的128例低位直肠癌中行直肠全系膜切除(TME)且应用国产管状吻合器及荷包钳进行手术的91例患者的资料。结果 全组无手术死亡病例,保肛均获成功,保肛率为71.09%(91/128),术后病理检查肿瘤远端切缘无癌残留。未发生吻合口出血及狭窄; 1例(1.10%)发生吻合口漏,经保守治疗后痊愈; 无大便失禁发生。全组获随访1~5年,平均3.8年,局部复发6例(6.59%); 总的1年生存率为97.80%(89/91),3年生存率为80.00%(72/90),5年生存率为68.97%(60/87)。结论 TME联合国产管状吻合器及荷包钳应用于低位直肠癌根治术,可提高保肛率,操作简单安全,疗效满意。
ObjectiveTo compare oncologic and short-term outcomes between the robotic and laparoscopic total mesorectal excision for rectal cancer. Methods This is a retrospective cohort study using a prospectively collected database. Patients’ records were obtained from Gansu Provincial Hospital between July 2015 and October 2017. Eighty patients underwent robotic-assisted total mesorectal excision (R-TME group) and one hundred and sixteen with the same histopathological stage of the tumor underwent an laparoscopic total mesorectal excision (L-TME group). Both operations were performed by the same surgeon. Results The time to the first passage of flatus [(3.28±1.64) d vs. (6.01±2.77) d, P<0.001], the time to the first postoperative oral fluid intake [(4.46±1.62) d vs. (6.28±2.74) d, P<0.001) and the length of hospital stay [(11.20±5.80)d vs. (14.72±6.90) d, P=0.023] of the R-TME group was about 3 days faster than the L-TME group. The incidence of postoperative urinary retention (2.50% vs 7.76%, P=0.016) was significantly lower in the R-TME group than the L-TME group. However, the intraoperative blood loss of the R-TME group was more than the L-TME group [(175.06±110.77) mL vs. (123.91±99.61) mL, P=0.031, ). The operative time, number of lymph nodes harvested and distal margin were similar intergroup(P>0.05). The total cost was higher in the R-TME than in the L-TME group [(85 623.91±13 310.50) CNY vs. (67 356.79±17 107.68) CNY, P=0.084), however, this difference was statistically insignificant. ConclusionsCompared with the L-TME, the R-TME has the same oncologic outcomes and rapid postoperative short-term recovery. However, the long-term outcome of the R-TME remains to be further observed.
Objective To systematically review the efficacy of robotic, laparoscopic-assisted, and open total mesorectal excision (TME) for the treatment of rectal cancer. Methods The PubMed, EMbase, The Cochrane Library, and ClinicalTrials.gov databases were electronically searched to identify cohort studies on robotic, laparoscopic-assisted, and open TME for rectal cancer published from January 2016 to January 2022. Two reviewers independently screened the literature, extracted data, and evaluated the risk of bias of the included studies. Subsequently, network meta-analysis was performed using RevMan 5.4 software and R software. Results A total of 24 studies involving 12 348 patients were included. The results indicated that among the three types of surgical procedures, robotic TME showed the best outcomes by shortening the length of hospital stay, reducing the incidence of postoperative anastomotic fistula and intestinal obstruction, and lowering the overall postoperative complication rate. However, differences in the number of dissected peritumoural lymph nodes were not statistically significant. Conclusion Robotic TME shows better outcomes in terms of the radicality of excision and postoperative short-term outcomes in the treatment of rectal cancer. However, clinicians should consider the patients’ actual condition for the selection of surgical methods to achieve individualised treatment for patients with rectal cancer.