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find Author "刘倩茜" 2 results
  • Current Situation of Diagnosis and Treatment of COPD in Western Rural Area of China

    ObjectiveTo evaluate the disease characteristics,medical consultation model and barrier to get basic medical service rural patients with chronic obstructive pulmonary disease(COPD) in Chinese western. MethodsThe subjects were collected from a COPD epidemiology study conducted in Western rural district.The factors which were associated with disease characteristics,medical consultation model,and barrier to get basic medical service were analyzed by questionnaire,individual conversation,and laboratory tests. ResultsThis study enrolled 343 COPD patients confirmed by spirometry test.118 subjects consulted their doctors frequently because of apparent symptom.73(62%) subjects had symptom with 5 to 10 years,while 22(19%) subjects with more than 10 years.Among the symptomatic COPD subjects,only 2(2%) cases were diagnosed as COPD previously,15(13%) subjects with chronic bronchitis,and only 1(1%) subject underwent spirometry test.110(93%) subjects were prescribed as antibiotics,68(58%) subjects with theophylline,5(4%) subjects with ICS+LABA.COPD education was acceptable in most subjects(98%),however,the regular follow-up was acceptable in only 26% of subjects. ConclusionLack of disease information,inappropriate medical consultation model,and irregular COPD management in primary care are the major factors which influence diagnosis and treatment of COPD in Western rural area of China.

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  • 侵袭性肺迟缓曲霉病一例报道

    目的 通过本病例及综述以提升对侵袭性肺迟缓曲霉病早期病原学诊断的重视,并为治疗方案提供参考依据。方法 回顾我科诊治的1例COVID-19感染后继发的侵袭性肺迟缓曲霉病患者的临床资料,复习既往文献总结分析肺迟缓曲霉病的临床表现、诊断及治疗用药方案。结果 患者79岁,老年男性,咳嗽、咳痰伴呼吸困难4月余。胸部CT提示:双肺数个结节灶,部分结节内空洞形成;散在实变影。G实验、GM结果阴性。气管镜肺泡灌洗液送检mNGS查见迟缓曲霉菌。给予伏立康唑治疗后效不佳,且继发肝功能异常,调整为艾沙康唑治疗后临床症状及肺部影像学征象好转。复习文献,共有12例个案报道,其中8例存在免疫抑制状态,4例合并慢性阻塞性肺病,6例为器官移植术后。临床选药以伏立康唑和两性霉素B居多,虽经治疗仍有66.7%(8例)患者在确诊后7周内死亡。结论 本例为国内外首次使用艾沙康唑成功治疗侵袭性肺迟缓曲霉病的报告。侵袭性肺迟缓曲霉病属于罕见病,免疫抑制状态是其高危因素。该病进展迅速,具有高度耐药性,预后差,病死率高,早期病原学诊断尤为关键。

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