Objective To compare the clinical effect of continuous renal replacement therapy (CRRT) and intermittent hemodialysis (IHD) in the treatment of severe acute renal failure (ARF). Methods A hundred patients with severe ARF treated between May 2011 and December 2014 were chosen to be the study subjects. According to the order of admission, they were divided into control group and observation group with 50 patients in each. Patients of the control group underwent IHD, while those in the observation group underwent CRRT. Serum creatinine (Scr), blood urea nitrogen (BUN), endogenous creatinine clearance rate (Ccr), treatment effective rate and survival rate were compared between the two groups before and after the treatment. Results Scr, BUN and Ccr were all improved after treatment in both the two groups. However, Scr, BUN and Ccr in the observation group [(225.1±162.7) μmol/L, (14.2±9.3) mmol/L, (23.4±10.5) mL/min] were significantly better than those in the control group [(588.4±183.6) μmol/L, (29.1±10.4) mmol/L, (15.9±8.2) mL/min]. The treatment effective rate and patients’ survival rate in the observation group were respectively 60% and 70%, both significantly higher than those in the control group (40% and 52%) All the differences were significant (P<0.05). Conclusion CRRT is superior in the treatment of severe ARF with a higher survival rate of the patients, which is worthy of clinical promotion.
ObjectiveTo find the ideal position of lag screw internal fixation in the anterior column of acetabulum by digital technology, and measure its related parameters, so as to improve the accuracy of lag screw implantation.MethodsThe CT scan data of 266 semi-pelvic raw in 133 cases (78 males and 55 females, aged 18-65 years old with an average age of 42 years) were collected between January 2019 and January 2020 to compose three-dimensional models. According to the relationship between the peripheral bone cortex of the anatomical channel and the lag screw, a new standard for the ideal position of lag screw fixation in the anterior column of acetabulum was proposed to simulate the implantation of the screw. After the screw was in the ideal position, the following indicators were measured: the maximum allowable diameter of the virtual screw (the diameter of the cylinder up to the new standard, R), the length (the distance between the center of the nail point on both sides, L); the position of the retrograde nail point (the interval between the nail insertion points and the midpoint of the pubic symphysis and the pubic tubercle, respectively, D1 and D2) and the position of the antegrade nail insertion point (the distance between the nail insertion point and the anterior superior iliac spine, the major ischial notch, and the vertical distance between the nail insertion point and the apex of the posterior upper edge of the acetabulum, respectively, D3, D4, D5); and the direction of the virtual screw at the ideal position (the angle between the screw and the horizontal plane, sagittal plane, and coronal plane, respectively, ∠β, ∠γ, ∠δ) were calculated.ResultsThe maximum allowable diameter of virtual screws was 5.70-14.10 mm for males, with an average of 9.25 mm; for females, it was 4.40-10.40 mm with an average of 7.29 mm. The antegrade insertion point of the anteroposterior acetabular lag screw was located at 2.0-2.5 cm above the apex of the acetabulum, which was almost the same distance from the anterior superior iliac spine and the ischial notch, about 5 cm; the insertion point of the retrograde implant was located at the pubic bone 2.5-3.0 cm below the nodule. When the acetabular anterior column screw was in the ideal position, there was no significant difference in the comparison of ∠β and ∠γ between the male and the female (P>0.05), and the differences in the other indicators were significant (P<0.05). Except for D4 and ∠β showing no significant difference between the left and right sides (P>0.05), the differences in the other indicators were significant (P<0.05).ConclusionIn the bony channel of the anterior column of the acetabulum, all males can accommodate screws with a diameter of <5.70 mm, and females can accommodate screws with a diameter of <4.40 mm. The anterograde or retrograde screw insertion points are different for male and female. The use of digital technology to individually measure the appropriate screw parameters can improve the accuracy and stability of the lag screw internal fixation for acetabular anterior column fractures.
目的 探讨腹腔镜术后Trocar部位疝的发生、分型和诊治方法。方法 1例77岁的女性患者，因“右附件囊性畸胎瘤”行腹腔镜右附件切除术，术后2 d出现右下腹Trocar部位疝并发肠梗阻，结合文献对其发生率、分型、发病因素、临床表现、诊治原则及预防进行分析。结果 手术证实部分小肠嵌顿于Trocar切口内，行小肠松解和切口缝合术，术后3 d痊愈出院。结论 Trocar部位疝并不少见，因素复杂，根据发生的时间和形态可将其分为早发型、迟发型和特殊型3型； 多需要手术治疗，缝合Trocar切口筋膜是有效的预防方法。
Objective To develop a new kind of skin substitute, selective acellular porcine skin, to cover excised wounds in treatment of extensivedeep burns on the basis of controlled de-cell technique. Methods Partial thickness porcine skin was treated with 0.25% trypsin for 2 hours at 37℃ after crosslinked with glutaraldehyde, and then it was glued to a container with the edge embedded with glue. The skin was shaken in 0.5% SDS for 24 hours, and then washed before use. The selective acellular skin was used with micro-autografts on the dermal side to cover 2 surgically excised burn wounds in a patient. The recoveries of function and appearance were observed. Results Morphological observation showed that the treated porcine skin had an intact epithelial layer and an acellular dermis. After being used to cover burn wounds, its acellular dermis could serve as host dermal matrix, and its devitalized epithelial layer could prevent the dermis from drying. The devitalized epithelium wasfinally replaced by host epithelial cells, and the healed wounds could achieve good cosmetic and functional results. Conclusion Selective acellular porcine skin can be used as promising skin substitute to cover excised wounds.
摘要:目的: 探讨动脉硬化闭塞症(ASO)和静脉血栓形成(VT)患者同型半胱氨酸(Hcy)变化。 方法 :通过循环酶法对34例非动脉硬化闭塞症(ASO)和静脉血栓形成(VT)患者(对照组),30例动脉硬化闭塞症(ASO)患者和26例静脉血栓形成(VT)患者血液中Hcy进行测定。 结果 :循环酶法测定HCY的批内平均变异系数为2．23％,批间平均变异系数为1．59％。34例对照组,〖WTBX〗t =1135,〖WTBX〗P =0266gt;005;动脉硬化闭塞症(ASO)组Hcy含量明显高于对照组(〖WTBX〗P lt;O．05),静脉血栓形成(VT)组Hcy含量高于对照组(〖WTBX〗P lt;0．O5)。 结论 :高同型半胱氨酸血症可能是动脉硬化闭塞症(ASO)和静脉血栓形成(VT)及复发的致病因素。可将同型半胱氨酸作为动脉硬化闭塞症(ASO)和静脉血栓形成(VT)及复发的重要指标。Abstract: Objective: TO syudy the changes of the Homocysteine about Atherosclerosis obliterans and Venous thrombosis patients. Methods : To measure the Hcy in the blood of 34 healthy cases both non ASO and non VT(the comparison group),30 cases of ASO patients and 26 cases of VT patients respectively by enzymatic cycling assay。〖WTHZ〗Results :The average variation coefficient of Hcy within the groups was 223% and among the groups was 159% measured by enzymatic cycling assay.In the 34 cases of comparison group,t=1135,P=0266gt;005,The content of Hcy in the blood of ASO patients group were significantly higher than the comparision group (Plt;005),and the content of Hcy in the blood of VT patients group were also higher than the comparison group (Plt;005). Conclusion : Hyper Hcy may be the pathogenic diathesis to form or to recrudesce ASO and VT.So we can treat Hcy as the significant index to form or to recrudesce ASO and VT.