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find Author "刘鉴峰" 3 results
  • 带蒂组织瓣在下肢软组织恶性肿瘤治疗中的应用

    【摘 要】 目的 探讨带蒂组织瓣修复下肢软组织恶性肿瘤切除后组织缺损的临床效果。 方法 1997年7月-2008年4月,收治15例下肢软组织恶性肿瘤患者。男11例,女4例;年龄30~55岁,平均41岁。肿瘤部位:前足2例,足跟6例,踝部4例,小腿2例,腘后1例。肿瘤切除后组织缺损范围为5 cm × 4 cm~20 cm × 12 cm,分别采用足底内侧皮瓣或肌皮瓣(5例)、 腓肠神经营养皮瓣(5例)、 外踝上皮瓣(3例)、 小腿内侧皮瓣(1例)、 缝匠肌皮瓣(1例)修复创面,皮瓣切取范围5.0 cm × 4.5 cm~22 cm × 14 cm。供区直接缝合或游离植皮修复。 结果 术后5~6 d 2例皮瓣部分坏死,术后10 d 1例供区植皮部分坏死,经换药后愈合;其余皮瓣及植皮均成活,创面Ⅰ期愈合。患者均获随访,随访时间1~12年,平均5.2年。2例患者因肿瘤转移死亡,3例局部复发;其余患者皮瓣质地、外观良好,肢体功能良好。获随访5年以上11例,5年生存率为73.3%(11/15)。 结论 根据肿瘤部位选择不同的带蒂皮瓣和肌皮瓣修复肿瘤扩大切除后组织缺损能最大限度减少肢体功能损害,保肢率高。

    Release date:2016-08-31 04:22 Export PDF Favorites Scan
  • PROCEDURE OF RECONSTRUCTING TRANSVERSE ARCH OF THE FOREFOOT BY TRANSFERING TENDONS FOR CORRECTING HALLUX VALGUS

    ObjectiveTo explore the effectiveness of the procedure of reconstructing the transverse arch of the forefoot by anastomosing adductor hallucis and abductor hallucis tendons in correcting hallux valgus. MethodsA retrospective analysis was made on the clinical data from 28 patients (40 feet) with hallux valgus treated with the procedure of reconstructing the transverse arch of the forefoot by anastomosing adductor hallucis and abductor hallucis tendons between January 2010 and January 2014. There were 3 males (6 feet) and 25 females (34 feet), with an average age of 51.7 years (range, 20-71 years). The unilateral foot was involved in 16 cases and bilateral feet in 12 cases. The mean disease duration was 8.9 years (range, 1-30 years). All the cases had pain of the first metacarpophalangeal joint; 22 feet had collapsed transverse arch of the forefoot combined with plantar callus, and 8 feet had collapsed transverse arch of the forefoot combined with hammer toe deformity. American Orthopaedic Foot and Ankle Society (AOFAS) score was 59.07±8.49. Preoperative X-ray showed that the hallux valgus angle (HVA) was (33.68±8.10)°, and the intermetatarsal angle (IMA) was (15.60±4.07)°. According to classification of the hallux valgus by Mann, 9 feet were rated as mild, 23 feet as moderate, and 8 feet as severe. ResultsSuperficial infection of incision occurred in 1 case (1 foot) after surgery, and healing by first intention was obtained in the others. Two cases (3 feet) had numbness in the toes. All of 28 cases were followed up from 6 months to 4 years (1.8 years on average). Based on the AOFAS score, the results were excellent in 24 feet, good in 9 feet, fair in 4 feet, and poor in 3 feet, and the excellent and good rate was 82.5%. At last follow-up, the HVA, IMA, and AOFAS score were (15.10±5.28)°, (9.05±2.42)°, and 86.03±7.45 respectively, showing significant differences compared with preoperative ones (P=0.00). The collapsed transverse arch of the forefoot was recovered to some extent, plantar callus disappeared (14 feet), or decreased (8 feet). Recurrence of hallux valgus deformity was observed in 2 cases (3 feet) at 2 and 3 months after surgery respectively, and no hallux varus was found. ConclusionThis procedure not only can effectively reduce the increased hallux valgus angle, and narrow the angle between the 1st and 2nd metatarsal, but also can relocate the sesamoid system, reconstruct the transverse arch of the forefoot, and effectively restore the physiological anatomy structure and biological function of the forefoot.

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  • Analysis of Adverse Drug Reaction in 680 Patients with SARS in Xiao Tang Shan Hospital

    Objective To investigate the adverse drug reactions (ADRs) of patients with SARS in Xiao Tang Shan Hospital. Methods We developed and distributed Drug Use Handbook and established ADRs monitoring group to guide resaonable drug use. We followed up the process and collected clinical report on ADRs. We retrospectively analyzed the data on ADRs by the classification and grade of ADRs according to WHO and Hospital Information Sysytem (HIS) of Chinese PLA General Hospital. Results We collected 193 (87 males and 106 females) patients with ADRs among 680 SARS patients with incidence rate of ADRs of 28.38%. The ADRs incidence rate was higher in females and elders. Critical SARS patients and SARS patients with diabetes were more susceptible to ADRs. Large dosage and combination of drugs may induce ADRs. Steroids may be a main cause of ADRs. The ADRs incidence rate induced by injection was higher than that induced by all kinds of oral drugs. ADRs mainly happened in hematological, endocrine and digestive systems. Conclusion SARS patients are prescribed many kinds of medications. Large dosage of so many medications may lend to high incidence rate of ADRs. Steroid should be cautiously used in the treatment of SARS.

    Release date:2016-09-07 02:27 Export PDF Favorites Scan
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