Objective To review the research progress of the current methods of inducing bone marrow mesenchymal stem cells (BMSCs) to chondrogenic differentiation in vitro so as to provide references for researches in cartilage tissue engineering. Methods Various methods of inducing BMSCs differentiation into the chondrogenic l ineage in vitro inrecent years were extensively reviewed and analyzed. Results Adding exogenous growth factors is still the mainly methodof inducing BMSCs differentiation into the chondrogenic l ineage; among the members, transforming growth factor β (TGF-β) family is recognized as the most important chondrogenic induction factor. Other important inducing factors include various chemical factors, physical factors, transgenic methods, and the microenvironmental induction. But the problems of low inducing efficiency and unstable inducing effects still exist. Conclusion The progress of chondrogenic induction of BMSCs promotes its util ization in cartilage tissue engineering. Further researches are needed for establ ishing more efficient, simpler, and safer inducing methods.
【摘要】 目的 探讨CT引导下经椎弓根穿刺活检对椎体病变的诊断价值及可行性。 方法 回顾性分析2009年5月—2010年4月42例椎体病变患者经椎弓根穿刺活检的穿刺活检方法、病理结果、最终诊断及穿刺并发症。 结果 患者总穿刺准确率为95.2%（40/42）。其中恶性病变的穿刺准确率为94.3%（33/35），良性病变穿刺准确率为100%（7/7）；所有患者均未发生严重穿刺并发症。 结论 CT引导下经椎弓根穿刺活检诊断椎体病变有安全可靠、准确性高等特点。【Abstract】 Objective To explore the value and the feasibility of CT guided transpedicular biopsy in diagnosing vertebral body lesions. Methods From May 2009 to April 2010, 42 patients with vertebral body lesions underwent CT guided transpedicular biopsy. The clinical data including the puncture method, pahtological resutls, final diagnosis, and the pucture complications were retrospectively analyzed. Results The total accuracy rate of the puncture was 95.2%(40/42). The accuracy rate of the puncture was 94.3% (33/35) for malignant lesions and 100.0% (7/7) for benign lesions. No complication occurred. Conclusion CT guided transpedicular biopsy is very helpful in diagnosing vertebral body lesions with high accuracy and fewer complications.
目的：探讨宫颈残端肿瘤的外科治疗方法及手术技巧，提高外科治疗水平。方法：回顾性分析我院自2005年5月至2007年11月手术治疗的宫颈残端肿瘤22例。结果：全组病例行不同程度的残余宫颈切除术，16例辅以不同程度的放疗或化疗，全切率100%，无手术相关死亡，3例并发膀胱损伤，术后恢复良好。结论：根治性手术风险高，难度大，只有根据病情采取合理的术式，掌握手术技巧，宫颈残端肿瘤才望获得较好的疗效。
Objective To investigate the influence of self-care and self-efficacy intervention on the quality of life of patients undergoing chemotherapy after surgery for gastric cancer. Methods Sixty-four patients undergoing chemotherapy after gastric cancer surgery between July 2014 and February 2015 were selected as the study subjects. According the sequence of admission, they were divided into intervention group (n=34) and control group (n=30). Patients in the control group accepted conventional care, while those in the intervention group received self-efficacy and self-care interventions. The scores of General Self-efficacy Scale (GCES), Exercise of Self-care Agency (ESCA), and Quality of Life Instruments for Cancer Patients-Stomach Cancer (QLICP-ST) were compared between the two groups before and after intervention. Results After intervention, GCES scores of the intervention group and the control group were respectively (30.08±4.21) and (20.78±4.58) points; the total scores of ESCA were respectively (132.30±14.81) and (92.45±13.23) points; and the total scores of QLICP-ST were respectively (75.96±9.41) and (56.77±10.32) points. All the above differences between the two groups were significant (P<0.05). Conclusion Self-care and self-efficacy intervention can improve self-care ability and self-efficacy, and improve the quality of life of patients undergoing chemotherapy after gastric cancer surgery.