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find Keyword "剖宫产术后" 2 results
  • 自控静脉镇痛在剖宫产产妇术后镇痛中的效果评价

    目的观察自控静脉镇痛(PCIA)在剖宫产产妇术后镇痛中的效果。 方法选取2013年6月-12月行剖宫产且术后疼痛视觉模拟评分(VAS)>4分需进行药物止痛产妇79例,其中自愿选取肌肉注射哌替啶镇痛的29例产妇纳入对照组,其余50例采用PCIA(舒芬太尼150μg+托烷司琼5 mg+生理盐水共150 mL)镇痛方式的产妇纳入观察组,分别在术后2、4、6、12、24 h对两组产妇疼痛程度、24 h睡眠质量、不良反应、镇痛满意度进行比较。 结果两组产妇术后不同时点的疼痛程度,24 h睡眠质量、不良反应比较,观察组优于对照组,差异有统计学意义(P<0.05),观察组镇痛满意率优于对照组,差异有统计学意义(P<0.05)。 结论PCIA能长久持续地减轻剖宫产产妇术后的疼痛,有效提高产妇术后睡眠质量,降低不良反应。

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  • Efficacy and safety of sufentanil versus fentanyl for patient-controlled intravenous analgesia after cesarean section: a systematic review

    ObjectivesTo systematically review the efficacy and safety of sufentanil versus fentanyl used in patient-controlled intravenous analgesia (PCIA) after cesarean section.MethodsAn online search of computerized searches of the database of MEDLINE (OVID), Web of Science, The Cochrane Central Register of Controlled Trials, PubMed, EMbase, CNKI, WanFang Data, VIP and SinoMed were conducted. Randomized controlled trials published since the inceptions of these databases until April 1st 2018, involving the comparison of sufentanil versus fentanyl for PCIA after cesarean section were included. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then, meta-analysis was conducted using the RevMan 5.1 software.ResultsA total of 19 studies were included. The results of meta-analysis showed that, compared with the fentanyl group, the sufentanil group had statistically significant lower VAS scores at 4-hour (MD=–0.99, 95%CI –1.03 to –0.95, P<0.001), 8-hour (MD=–0.30, 95%CI –0.40 to –0.21, P<0.001), 12-hour (MD=–0.54, 95%CI –0.62 to –0.46, P<0.001) and 24-hour (MD=–0.35, 95%CI –0.41 to –0.28, P<0.001); statistically significant higher Ramsay scores at 4-hour (MD=0.72, 95%CI 0.66 to 0.78, P<0.001), 8-hour (MD=0.93, 95%CI 0.86 to 1.00, P<0.001), 12-hour (MD=0.98, 95%CI 0.91 to 1.05, P<0.001), 24-hour (MD=0.07, 95%CI 0.03 to 0.11, P=0.000 5), 48-hour (MD=0.05, 95%CI 0.03 to 0.08, P<0.000 1). As for the adverse reactions, sufentanil group had lower risks of having nausea and vomiting (RR=0.25, 95%CI 0.19 to 0.31, P<0.001), pruritus (RR=0.41, 95%CI 0.30 to 0.57, P<0.001), dizziness (RR=0.27, 95%CI 0.17 to 0.44, P<0.001) and urinary retention (RR=0.35, 95%CI (0.15, 0.82), P=0.02).ConclusionsThe current evidence shows that, sufentanil has better analgesia and sedative effects, and less risks of adverse reactions for safer clinical use.

    Release date:2019-03-21 10:45 Export PDF Favorites Scan
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