west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "卢蓉" 3 results
  • 腺苷对犬体外循环后肺缺血-再灌注损伤的作用

    目的 研究腺苷是否能减轻体外循环后肺组织损伤。 方法 12条犬随机分为实验组和对照组。建立体外循环模型,实验组使用腺苷(50μg/kgmin)中心静脉持续滴注;对照组滴注生理盐水。分别于各时间点测定血流动力学、右心功能和动脉血气分析;测定肺组织含水量、丙二醛含量,并进行病理分析。 结果 两组心率、体循环平均动脉压、左心房压、中心静脉压比较无差异,与对照组比较实验组体外循环后肺血管阻力降低,右心功能改善,动脉血氧分压明显升高;肺组织含水量较少,肺组织丙二醛含量较低(P<0.05或P<0.01)。病理检查:实验组犬肺泡结构正常,无明显中性粒细胞浸润。 结论 腺苷能够减轻体外循环后肺缺血-再灌注损伤,改善右心功能,在一定剂量范围内并不对体循环血流动力学构成明显影响。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
  • 重症监护病房呼吸道耐甲氧西林金黄色葡萄球菌感染概况及控制对策

    目的探讨重症监护病房耐甲氧西林金黄色葡萄球菌(MRSA)感染的概况及控制对策。 方法对重症监护病房2012年1月-12月的23例呼吸道感染MRSA的患者进行回顾分析,并提出防控措施。 结果高龄、免疫低下、侵袭性操作频繁、住院时间长、使用广谱抗菌药物和抑酸剂使用量大且时间长是患者发生MRSA感染的危险因素。 结论应采取合理必要的防控措施防止院内交叉感染,并积极治疗和精心护理患者促进其康复,以控制MRSA在医院内的发生和流行。

    Release date: Export PDF Favorites Scan
  • Effect of Endothelin Receptor Antagonists on Recent Outcomes of Patients Undergoing Fontan Surgery: A Prospective Study

    ObjectiveTo study the effect of endothelin receptor antagonist on recent outcome of patients undergoing Fontan surgery. MethodsThirty nine patients who received Fontan procedure from January 2009 to December 2010 in Wuhan Asia Heart Hospital were recruited in the study. There were 25 males and 14 females with mean age of 8.02±4.98 years (ranged from 2.5 to 18.0 years). According to the admission number, the patients were randomly divided into an endothelin receptor antagonists group (bosentan group, n=16) and a control group (n=23). The bosentan group received bosentan treatment by gastric fill or oral according to the recommended dose in three days after surgery for over 7 days. The control group did not receive any pulmonary hypertension targeted therapy. On the 10th day after surgery, indexes including mortality etc in the two groups were compared. ResultsNo death occurred in the bosentan group. One patient died on the 5th day after operation in the control group. There was no significant difference in the postoperative mortality. The patients in the bosentan group got significantly better results than the control group in cardiac function, incidence of pleural effusion, vasoactive drugs score, and serum B-type natriuretic peptide, albumin, alanine aminotransferase on the 10th day (P < 0.05); while the 6-minute walk distance, transcutaneous oxygen saturation, white blood cell count, C-reactive protein, cardiac troponin I, and creatinine of the two groups showed no statistical difference (P > 0.05). ConclusionEndothelin receptor antagonists can improve the short-term outcome of patients after Fontan surgery.

    Release date:2016-10-02 04:56 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content