Objective To approach whether the postoperative recovery processes of the living donors and hepaticpatients after right hepatectomy is similar. Methods The clinical data of consecutive cases from 2009 to 2010 in our liver transplantation center was retrospectively analyzed, including 40 cases who donated the right lobe without the middlehepatic vein (living donor liver transpalntation-donor group, abbreviated as LDLT-D group) and 80 hepatic patients forright hepatectomy, in which 40 cases were hepatic patients without cirrhosis (liver disease-noncirrhosis group, abbreviatedas LD-NC group) and 40 cases were hepatic patients with cirrhosis (liver disease-with cirrhosis group, abbreviated asLD-WC group). Preoperative liver function and general clinical data, intraoperative blood loss and transfusion, postoper-ative liver function, and complications were statistically analyzed in this study. Results The preoperative parameters of three groups were comparable. LDLT-D group experienced more intraoperative bleeding than LD-NC group 〔(765±411) mL vs. (584±242) mL, P=0.008〕, and was similar to LD-WC group 〔(666±224) mL, P=0.136〕. However, the average amount of blood transfusion products was similar among the 3 groups (P=0.108). The levels of total bilirubin and INR of LDLT-D group were higher than LD-NC group and LD-WC group on the first and third day after operation (P<0.05). The levels of ALT and AST of LD-WC group were higher than LDLT-D group and LD-NC group (P<0.05). The overall postoperative surgical morbidity incidence of LDLT-D group, LD-NC group, and LD-WC group were 30.0%(12/40), 27.5% (11/40), and 37.5% (15/40) respectively, and were not statistically significant (P=0.606). However, the ClavienⅢcomplication rate of LD-WC group was higher than LDLT-D group and LD-NC group 〔27.5% (11/40) vs. 7.5%(3/40) and 10.0% (4/40), P=0.024〕. Conclusions Liver function of living donors is injured more seriously during the early postoperative period. The total complication rates after right hepatectomy are similar among the living liver donation and hepatic patients with or without cirrhosis. However, the serious complication rate of cirrhotic liver recipients is higher than living donors and patients without cirrhosis.
ObjectiveTo investigate the clinical application of laparoscopic right hemihepatectomy via anterior approach. MethodThe clinical data of 32 patients underwent laparoscopic right hemihepatectomy via anterior approach from June 2017 to May 2019 were retrospectively analyzed.ResultsThe laparoscopic right hemihepatectomies via anterior approach were successfully completed in the 32 patients, no one converted to laparotomy. The operation time was (315.5±36.7) min, the intraoperative bleeding was (340.8±105.4) mL, and the postoperative hospital stay was (8.9±1.7) d. The postoperative complications occurred in 6 cases, including 1 case of peritoneal effusion, 1 case of intraabdominal infection, 2 cases of bile leakage and 2 cases of pleural effusion combined with pulmonary infection, who were discharged after receiving the conservative treatment according to the symptoms. The results of postoperative pathology: 13 cases of hepatocellular carcinoma, 6 cases of intrahepatic cholangiocarcinoma, 7 cases of hepatic angioleiomyoma, 6 cases of intrahepatic bile duct stones. The average follow-up time was 12 months (range 1 to 24 months). During the follow-up period, 7 cases of hepatic angioleiomyoma and 6 cases of hepatolithiasis survived after operation. The intrahepatic metastases were found in 1 patient with hepatocellular carcinoma at 12 months and 2 cases of intrahepatic cholangiocarcinoma at 9 months and 11 months, respectively. The rest patients survived free tumor.ConclusionLaparoscopic right hemihepatectomy via anterior approach is safe and feasible, and has a satisfactory short-term efficacy.