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find Author "叶俊" 6 results
  • Endobronchial Electrocautery Treatment of Tracheobronchial Obstructive Lesions in Inoperable Tracheobronchial Squamous Cell Carcinoma

    Obstractive To observe the clinical effects and safety of endobronchial electrocautery treatment for tracheobronchial obstructive lesions in inoperable tracheobronchial squamous cell carcinoma.Methods Ninety-five patients with advanced and inoperable tracheobronchial squamous cell carcinoma were included. Thirty-four patients with central airway obstruction were treated with endobronchial electrocautery plus chemotherapy ( group A) and 61 patients without central airway obstruction were treated with chemotherapy alone ( group B) . The chemotherapy consisted of cisplatin or carboplatin, plus another thirdgeneration chemotherapy agent. Results In groug A, there were mean improvements in FEV1 of 41. 1% and in peak expiratory flow( PEF) of 65. 6% . There was no significant difference in the survival rates of the patients with and without central airway obstruction. Median survival time of group A was 11. 3 months and those of group B was 11. 6 months. 3, 6, and 12-month survival rates in group A were 87% , 68% and 39% respectively, and those in group B were 93% , 76% , and 45% respectively. Conclusion Endobronchial electrocautery is an effective and safe approach for inoperable tracheobronchial obstructive malignancies with few complications.

    Release date:2016-09-14 11:25 Export PDF Favorites Scan
  • 经支气管镜介入治疗中心性气道狭窄

    Release date:2016-08-30 11:56 Export PDF Favorites Scan
  • 单克隆抗体在难治性哮喘中的治疗进展

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  • Tracheobronchopathia Osteochondroplastica: Two Cases Report and Literature Review

    Objective To investigate the manifestations, diagnosis and treatment of tracheobronchopathia osteochondroplastica ( TO) . Methods Two cases of TO were described and 76 cases in the medical literature after 2000 were reviewed. Results TO usually manifests in adults, and affects both genders. The clinical presentation of TO is nonspecific. Bronchoscopy remains the gold standard for diagnosing this condition. Hard sessile nodules arising from the anterior and lateral walls of the airway,typically sparing the posterior membrane, are classic appearance that can be easily recognized. The CT scan is more sensitive and specific, which plays an important role in the diagnosis of TO. Bronchial biopsies disclose the abnormal presence of cartilage and bone tissue in the bronchial submucosa. To date there is nospecific treatment for the disease. Only a minority of cases develop into significant upper airway obstruction and require invasive procedures to remove or bypass the obstacle on affected airways. Conclusions TO is a stable or slowly progressive benign disease. Chest computed tomography and fiberoptic bronchoscopy are thebest diagnostic procedures to identify TO.

    Release date:2016-08-30 11:52 Export PDF Favorites Scan
  • Radioactive 125I seed implantation in the treatment of unresectable pancreatic cancer

    ObjectiveTo investigate the current status and research progress of radioactive 125I seed implantation in the treatment of unresectable pancreatic cancer.MethodsReviewed the relevant literatures to summarize and analyze the mechanism of action, indications and contraindications, implantation methods, clinical efficacy, complications, and treatment measures of radioactive 125I seed implantation in the treatment of pancreatic cancer.ResultsThe mechanism of radioactive 125I seed implantation in the treatment of pancreatic cancer had been deeply studied in terms of gene expression and molecular signal level. The procedure was applicable to a wide range of patients; the implantation methods were abundant, CT and ultrasound guidance had their advantages; it could effectively inhibit tumor growth and improve overall survival rate. It was dramatically for pain relief, as well as low overall complication rate, and the complications could be alleviated by symptomatic treatment.ConclusionRadioactive 125I seed implantation in the treatment of unresectable pancreatic cancer has been widely promoted due to its simple operation and small trauma, and it is effective in controlling tumor growth, prolonging survival, and relieving pain.

    Release date:2019-11-25 02:42 Export PDF Favorites Scan
  • 电视胸腔镜手术治疗双侧肺大泡:同期手术优于分期手术

    目的 探讨电视胸腔镜手术(video-assisted thoracscopic surgery,VATS)在双侧肺大泡切除中的可行性、手术时机及治疗效果。 方法 回顾性分析2001年4月至2011年6月中山大学附属佛山医院佛山市第一人民医院应用电视胸腔镜施行同期或分期手术切除双侧肺大泡患者168例的临床资料,男135例,女 33例;年龄15~68(41.5±10.6)岁。依据手术方式不同分为同期手术组(92例)和分期手术组(76例)。分析两组患者围手术期及远期并发症发生情况,比较行双侧同期肺大泡手术的效果。 结果 168例患者均顺利完成手术,住院时间为7~16(6.6±2.4) d,无术中及术后死亡患者,2例因严重肺粘连中转开胸。术后随访6个月~10年,围手术期并发症同期手术组显著低于分期手术组,差异有统计学意义(P<0.05);远期并发症两组间差异无统计学意义(P>0.05);术后总体并发症同期手术组低于分期手术组,差异有统计学意义(P<0.05)。 结论 VATS同期或分期治疗双侧肺大泡疗效确切,行双侧同期手术效果更佳。

    Release date:2016-08-30 05:45 Export PDF Favorites Scan
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