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find Author "周健" 40 results
  • 高度近视黄斑病变及其治疗

    高度近视在世界各地是第4~7位的永久性致盲疾病。黄斑闻的漆裂纹样病变和脉络膜新生血管对中心视力有很大危害。前者是视网膜色素上皮-Bruch膜-脉络膜毛细管管复合体的机械性破裂的表现,为黄斑变性的早期改变;后者是Bruch膜破裂后脉络膜血管长入的结果,它的出现预示中心视力将受到更大威胁。巩膜加固术是目前试图阻止高度近视黄斑病变发展的唯一选择,但不能提高视力。激光治疗脉络膜新生血管在近期可延缓中心视力的下降,但远期效果不佳。这两种疗法还需大量随机临床试验证实。 (中华眼底病杂志,1993,9:120-124)

    Release date:2016-09-02 06:35 Export PDF Favorites Scan
  • Prevention, Diagnosis and Treatment of Biliary Tract Complications after Liver Transplantation

    【Abstract】ObjectiveTo investigate the causes of biliary tract complications after liver transplantation, and to put forward effective measures of prevention, diagnosis and treatment. MethodsThe literatures of recent years were reviewed and summarized. Results The causes of biliary tract complications after liver transplantation are very complex, and there are no standard preventive measures. Treatment differs according to causes. ConclusionOne of the most important causes leading to biliary complications is preservative and ischemic injury. Poorly operative techniques and blood supply to biliary tract are also disastrous. Improving T tube placement can reduce the incidence of biliary complications related with T tube. To prevent biliary complications, it is crucial to completely wash the biliary tract, avoid damaging the blood supply to donor biliary tract and manage perfect biliary mucosatomucosa anastomosis without tension. T tube cholangiography combined with noninvasive MRCP enables accurate depiction of the biliary tree and diagnosis of biliary complications. Doppler ultrosonography should be routinely applied postoperatively. Timely application of interventional radiological technique is a valuable nonoperative procedure for treatment of biliary complications. Meanwhile, biliary sludge or cholestasis and mixed infections of biliary tract should be handled actively and properly.

    Release date:2016-09-08 11:52 Export PDF Favorites Scan
  • 新生血管性青光眼睫状体冷凝后交感性眼炎一例

    Release date:2016-09-02 06:05 Export PDF Favorites Scan
  • ULTRASTRUCTURAL OBSERVATION OF THE SUBRETINAL MEMBRANE

    We observed 12(35.3%) cases of subretinal membranes in 34 patients with long-standing retinal detachments with proliferative vitreoretinopathy. Transmission electron microscopy revealed that glial cells, retinal pigment epithelial cells and a great amount of collagen represented the basic cellular and substantial components in a subretinal membrane obtained by vitreous surgery. (Chin J Ocul Fundus Dis,1994,10:165-166)

    Release date:2016-09-02 06:34 Export PDF Favorites Scan
  • Liver Retransplantation:Decision-Making and Challenge

    Release date:2016-09-08 10:24 Export PDF Favorites Scan
  • Clinical research progress of primary pulmonary lymphoepithelioma-like carcinoma

    Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare type of lung cancer with special characteristics of epidemiology, clinical diagnosis, treatment and prognosis. It has close relationship with Epstein-Barr virus (EBV) infection and has prominent regional feature. Most patients are young and non-smoking. There is no specificity of clinical manifestation. Most patients are asymptomatic at the time of diagnosis. As for treatment, the standard treatment for early stage disease is complete resection. Platinum-based doublet chemotherapy has been applied in locally advanced disease as the first line therapy. Due to its rarity, the treatment of advanced PPLELC is still lack of evidence of large sample randomized controlled trial. Whether target therapy or immunotherapy is effective is worth further study. This article reviews the research progress of PPLELC, to give a particular sight for clinicians and provides a better understanding of this rare tumor for researchers.

    Release date:2019-10-12 01:36 Export PDF Favorites Scan
  • Analysis and discussion of the research status of thoracoscopic and laparoscopicsimulation training and assessment

    Minimally invasive surgery is the development direction of surgery in the 21st century, and thoracoscopic or laparoscopic skills are essential skills that all surgeons must master. Thoracoscopic or laparoscopic skills training is an important part of surgical resident training. However, there are various methods for thoracoscopic or laparoscopic skill training internationally. The assessment is still in the stage of examiners’ visual observation and subjective evaluation. Here, we reviewed the current research status of thoracoscopic and laparoscopic simulation training and assessment, discussed the development experience and application achievements of Huaxi Intelligent Thoracoscopic Skill Training and Assessment System. We aimed to provide a theoretical basis and practical experience for the development of thoracoscopic or laparoscopic simulation education.

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  • 道诺霉素及脂质体对玻璃体切除兔眼视网膜的毒性

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  • 儿童睫状体、脉络膜黑色素瘤一例

    Release date:2016-09-02 05:37 Export PDF Favorites Scan
  • Relationship of spread through air spaces and specific clinicopathological features or poor prognosis of lung adenocarcinoma: A systemic review and meta-analysis

    ObjectiveTo assess the specific clinicopathological characteristics as well as prognostic value of prognostic significance of spread through air spaces (STAS) in lung adenocarcinoma.MethodsWe systematically searched the databases of PubMed, EMbase and Web of Science databases from their date of inception to March 2019. The quality of the included literature was assessed by the Newcastle-Ottawa scale (NOS). The NOS of the study higher than 6 points was considered as high quality. Software of Stata 12.0 was used for meta-analysis.ResultsTwenty retrospective cohort studies involved with totally 6 225 patients were included. Quality of included studies was high with NOS score equal or higher than 6 points. STAS was associated with male sex, ever smoking history, abnormal carcino-embryonic antigen (CEA) level, air bronchogram negative, anaplasticlymphoma kinase (ALK) arrangement positive, epidermal growth factor receptor (EGFR) mutation positive, advanced pathological tumor stage and more invasive pathological adenocarcinoma subtypes. The presence of STAS indicated significantly poor recurrence free survival (RFS) (HR=1.960, 95%CI 1.718-2.237, P<0.001) as well as poor overall survival (OS) (HR=1.891, 95%CI 1.389-2.574, P<0.001). Further subgroup analyses showed that exhibiting tumor size including diameter less than 2 cm (HR=2.344, 95%CI 1.703-3.225, P<0.001) and diameter over 2 cm (HR=2.571, 95%CI 1.559-4.238, P<0.001), resection type including lobectomy (HR=1.636, 95%CI 1.258-2.127, P<0.001) and sublobar resection (HR=3.549, 95%CI 2.092-6.021, P<0.001) in stageⅠ adenocarcinoma suggested that STAS had a bad effect on RFS.ConclusionPresence of STAS is associated with more aggressive clinicopathological features and independently associated with worse RFS and OS in lung adenocarcinoma. STAS positive has a negative effect on RFS whatever the tumor size (including the diameter<2 cm or >2 cm) and resection types in stageⅠ adenocarcinoma.

    Release date:2019-06-18 10:20 Export PDF Favorites Scan
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