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运动干预对乳腺癌患者术后体能、心理及生活质量的影响（附3例报道）

目的 探讨运动干预对乳腺癌患者术后体能、心理及生活质量的影响。 方法 回顾性分析笔者所在诊所对 3 例乳腺癌患者术后进行运动干预后的临床数据。 结果 3 例患者均完成了 3 次/周的运动训练。运动干预 12 次（4 周）时及运动开始至第3 个月时，除1例患者在运动干预至第12次时的生活质量评分有下降及1例患者因用药导致1 min心率回落速度降低外，3 例患者的体质量、心肺运动测试结果、功能性运动模式筛查结果、生活质量及心理状态均得到了改善。 结论 运动干预可能有利于乳腺癌患者术后的康复，待进一步积累病例验证。

胆囊结石患者血浆甲状旁腺激素相关蛋白和甲状旁腺激素的变化

Curative Effect Observation of Thrombin in Treatment of Subcutaneous Effusion Following Radical Resection of Breast Cancer

ObjectiveTo explore the efficacy of thrombin in treatment of subcutaneous effusion after radical resection of breast cancer. MethodsOne hundred and ninety patients underwent radical resection of breast cancer from July 2008 to July 2013 in this hospital were divided into postoperative observation group and postoperative control group according to the operation time. A daily injection of thrombin by drainage tube was performed on day 3 after operation in the postoperative observation group, the negative pressure drainage only was performed in the postoperative control group. The drainage volume in 72 h after operation, time of extubation, cases of subcutaneous effusion were counted after operation. Then the patients with subcutaneous effusion were divided into subcutaneous effusion observation group and subcutaneous effusion control group according to the time of extubation, the thrombin was injected into cavity after pumping subcutaneous effusion with pressing and dressing in the subcutaneous effusion observation group and only pressed after pumping subcutaneous effusion in the subcutaneous effusion control group, respectively. The healing time of subcutaneous effusion was counted in these two groups. ResultsCompared with the postoperative control group, the drainage volume in 72 h after operation was less(P < 0.001), the time of extubation was earlier(P < 0.001), the rate of subcutaneous effusion was lower(P < 0.05), color of drainage fluid on day 2 after mastectomy was lighter(P < 0.001)in the postoperative observation group. Compared with subcutaneous effusion control group, when subcutaneous effusion was 20-50 mL or > 50 mL, the healing time of subcutaneous effusion was significantly shorter in the subcutaneous effusion observation group(P < 0.05). ConclusionsInjecting thrombin by drainage tube after operation can reduce the drainage volume, decrease the rate of subcutaneous liquid, and shorten the time of extubation. Injecting thrombin into cavity of subcutaneous liquid can shorten the healing time of patients with middle and large subcutaneous effusions after radical resection of breast cancer.