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find Author "唐仕波" 28 results
  • 应努力推动我国糖尿病视网膜病变的临床基础研究

    Release date:2016-09-02 05:51 Export PDF Favorites Scan
  • 视网膜疾病的蛋白质组研究

    蛋白质组学是研究细胞内所有蛋白质的组成及其动态变化规律的科学,它是在蛋白质水平定量、动态、整体地研究生物体,并在更深层次上获得对疾病的发病机制、过程以及药物治疗靶点的新的认识,但在眼部尤其是视网膜中的研究尚处于起步阶段。现对蛋白质组学的概念、研究内容、相关技术和在视网膜中的研究现状进行综述。 (中华眼底病杂志,2005,21:199-202)

    Release date:2016-09-02 05:52 Export PDF Favorites Scan
  • 遗传性黄斑变性的分子遗传学研究进展

    遗传性黄斑变性是一组由遗传因素引起的脉络膜视网膜退行性病变,种类繁多,其遗传方式、发病机制并不清楚。近年来,分子遗传学的研究已初步揭示了该类疾病的相关致病基因位点,以及基因型与表型间的相互关系,从而加深了对其发病机制、遗传方式的认识。现将几种主要的遗传性黄斑变性的分子遗传学最新研究进展综述如下。 (中华眼底病杂志, 2002, 18: 323-324)

    Release date:2016-09-02 06:01 Export PDF Favorites Scan
  • 视网膜变性疾病基因治疗的研究进展

    分子生物学的进展为基因治疗视网膜变性疾病开拓了良好的应用前景,但目的基因的有效转染和长期表达等问题亟待解决,对有丝分裂后的视网膜感光细胞,解决这一问题就显得更为迫切。本文在阐述这些问题的研究现状的基础上对感光细胞的转基因营救及基因修饰的神经前体细胞回体移植的应用前景作一综述。 (中华眼底病杂志, 1999, 15: 268-270)

    Release date:2016-09-02 06:07 Export PDF Favorites Scan
  • 表观遗传调控在糖尿病视网膜病变中的研究进展

    遗传和环境因素均参与糖尿病及其并发症的病理过程, 表观遗传调控在其中的作用也日渐明确。糖尿病及其并发症中的主要病理过程如高血糖、氧化应激、炎症等均会导致表观遗传调控的异常, 从而影响染色质结构和基因表达, 而这些染色质表观遗传修饰的持续存在和糖尿病相关的代谢记忆现象相联系。表现机制相关的药物和治疗手段的研发或将成为糖尿病及相关并发症靶向治疗的新方面。

    Release date: Export PDF Favorites Scan
  • New insight into application and function of air or gas for vitreoretinal surgery

    At present, tamponade agent which being used in retinal surgery is mainly sterile air, gas and silicone oil. Sterile air is mostly used in the treatment of simple retinal detachment. Gas or silicone oil as tamponade is greatly applied for complicated retinal detachment. In recent years, with the application of micro-invasive vitrectomy under a wide-angle viewing system and perioperative anti-vascular endothelial growth factor drugs, application of intraocular filling materials also has changed. The application of silicone oil is significantly reduced. Percentage rate of gas as tamponade for retinal detachment is reduced. The application of sterile air as tamponade is rising. With selecting indication carefully and picking up the suitable air or gas, doctor will reduce the workload. It will also reduce the social burden and benefit patients.

    Release date:2022-05-18 04:03 Export PDF Favorites Scan
  • Objective evaluation of the effect of posterior scleral reinforcement surgery on the prevention and control of high myopia

    Due to the high incidence and the earlier onset age, high myopia has become an important public health problem in China. Posterior scleral reinforcement surgery has been developed for over 60 years in order to control the rapid progression and complications of high myopia. By suturing a certain size of material on the surface of the posterior eyeball, thickness and elasticity modulus of the local sclera significantly increase. As the result, the rapid growth of the axial length and the chorioretinopathy could be alleviated. At present, controversies about its clinical efficacy and safety still exist, so posterior scleral reinforcement surgery has not been widely carried out all over the world. An in-depth analysis of the mechanism, surgical manipulations and materials, the clinical application status of posterior scleral reinforcement surgery on control of high myopia can provide a basis for further standardized application of this surgery

    Release date:2023-09-12 09:11 Export PDF Favorites Scan
  • Strengthen innovation and development of vitreoretinal surgery in China

    Recent years have witnessed tremendous progress in vitreoretinal surgery. The treatment of vitreoretinal diseases has increased enormously and its related indications expanded widely with the contribution of the emerging novel technologies, methods, equipment and new ideas. Attaching importance to minimally invasive surgery, application of auxiliary drugs, development of improved equipment and surgical technique were the main features. Further basic and clinical research is necessary to promote innovation and development of vitreoretinal surgery in China to keep pace with and surpass advanced technology.

    Release date:2016-09-02 05:25 Export PDF Favorites Scan
  • Enhancing the research on the mechanism of the occurrence and development of retinal neovascularization to prevent and treat retinal neovascularization diseases

    Retinal neovascularization is a complicated pathophysiological process as a result of imbalance between angiogenic and antiangiogenic factors. Correct understanding of the signaling pathways, exploring the critical factors involved in retinal angiogenesis, looking for new strategies by reconstructing the new vessels are helpful for knowing the mechanism of the occurrence and development of reitnal neovascularization, which would be good for preventing and treating retinal neovascularization diseases.

    Release date:2016-09-02 05:41 Export PDF Favorites Scan
  • 巨噬细胞与小胶质细胞在老年性黄斑变性发病机制中的调控作用

    Release date:2016-09-02 05:41 Export PDF Favorites Scan
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