west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "唐利" 2 results
  • 联合用药不良反应信号检测研究进展

    临床联合用药目前已广泛使用,其安全性问题也随之引起广泛关注。而联合用药不良反应信号检测方法能快速有效地筛选药物相互作用信号,对加强合理联合用药及安全监测具有重要意义,有利于将有限的医疗资源集中于高度危险的药物组合。目前已有多种方法被尝试引入该领域,为给我国联合用药不良反应的研究与发展提供参考,现对国内外在药物安全警戒工作中所运用的联合用药不良反应信号检测方法及其优缺点作一综述。

    Release date: Export PDF Favorites Scan
  • Clinical characteristics and mortality risk factors analysis of heat stroke

    Objective To retrospectively analyze the clinical characteristics of heat stroke (HS) and HS-acute kidney injury (AKI), analyze the risk factors leading to death in patients, and provide new ideas for the prevention and treatment of HS. Methods Patients with HS who visited 13 hospitals in Sichuan subtropical monsoon climate and HS high-incidence areas between July 2019 and September 2023 were retrospectively selected. According to whether in-hospital death or AKI occurred, the patients were divided into survival group and death group, AKI group and non-AKI group. According to serum creatinine level, patients in the AKI group were divided into AKI stage 1 group, AKI stage 2 group and AKI stage 3 group. The main clinical manifestations and important clinical data of the patients were analyzed, and the risk factors affecting the death of patients were analyzed by multivariate logistic regression. Results A total of 195 patients with HS and 115 patients with HS-AKI were included. The results of multivariate logistic regression analysis showed that AKI, abnormal coagulation function, nervous system injury, neutrophil/lymphocyte ratio, and D-dimer were independent risk factors for death (P<0.05). The results of clinical characteristics analysis of HS-AKI showed that the mortality rate of patients with AKI stage 2 and AKI stage 3 was higher (P<0.05). Conclusions AKI, abnormal coagulation function, nervous system injury, neutrophil/lymphocyte ratio, and D-dimer are independent risk factors for death in HS. Therefore, active treatment of patients with HS combined with AKI, abnormal coagulation function, and nervous system injury in the future will help reduce the risk of death in patients.

    Release date:2024-07-23 01:47 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content