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find Keyword "妊娠滋养细胞肿瘤" 2 results
  • Placental Site Trophoblastic Tumor: Diagnostic and Therapeutic Advancement and A Case Report

    目的 通过对1例原发于宫颈的胎盘部位滋养细胞肿瘤(PSTT)的资料及相关文献的复习,全面介绍胎盘部位滋养细胞肿瘤的临床特征、病理特点、治疗方式及预后。 方法 对收治1例罕见原发于宫颈部位的PSTT的临床病理资料进行分析,并以“胎盘部位滋养细胞肿瘤”为主题词查阅中国知网(CNKI)及PubMed等文献数据库进行文献复习。 结果 该例原发于宫颈部位的PSTT患者术后化学疗法后,目前情况良好,已随访3年,无复发及转移征象。2011年9月1日前,CNKI数据库共报道300余例PSTT病例,PubMed数据库共160余例,其中有2例原发于宫颈部位的PSTT。原发于宫颈部位的PSTT罕见,易误诊,往往需要宫颈活组织检查或宫颈搔刮才能确诊。 结论 原发于宫颈部位的PSTT的预后是否遵循PSTT尚需收集更多的病例证实。PSTT因其发病率低,临床表现多无特异性,通常需要通过诊断性刮宫、活组织检查甚至术后病理检查才能确诊。PSTT首选的治疗方式为手术,多数患者病灶清除后可治愈,对有高危因素的患者术后宜选择依托泊苷+甲氨蝶呤+放线菌素D+环磷酰胺+长春新碱(EMA-CO)方案或依托泊苷+甲氨蝶呤+放线菌素D+依托泊苷+顺铂(EMA-EP)方案进行化学治疗,以期改善预后。

    Release date:2016-09-08 09:13 Export PDF Favorites Scan
  • Clinical pharmacists participating in the pharmaceutical care of a patient with low-risk gestational trophoblastic neoplasia

    Objective To explore the way of clinical pharmacists participating in formulating the chemotherapy regimen for cancer and pharmaceutical monitoring, through the practice of drug treatment in a patient with gestational trophoblastic neoplasia. Methods Clinical pharmacists participated in the treatment of one patient with low-risk gestational trophoblastic neoplasia in gynecological chemotherapy ward, from the first chemotherapy in January 2015 to the clinical cure. The countermeasures included designating chemotherapy regimen, monitoring clinical efficacy and adverse reactions, changing the chemotherapy regimen in time when the curative effect was poor, and coping with adverse reactions. Results Physicians adopted the suggestions from clinical pharmacists and the patient was clinically cured after standardized treatment. Conclusion Pharmaceutical care by clinical pharmacists can assist clinicians to ensure the safety and effectiveness of drug use.

    Release date:2018-04-23 05:00 Export PDF Favorites Scan
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