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Diagnostic Significance of Urinary Spot Protein:Creatinine Ratio in Eclampsia

【摘要】 目的 评价尿蛋白与尿肌酐比值检测在子痫患者中的诊断意义。 方法 回顾分析 35例子痫患者的临床资料。患者年龄20~34岁,平均年龄(2681±639)岁;孕周22~34周,平均孕周(2902±419)周。平均血压(15620±1235 )mm Hg(1 mm Hg=0133 kPa)。均检测24 h尿蛋白及点时尿检测尿蛋白与尿肌酐比值,采用线形回归分析尿蛋白与尿肌酐比值与24 h尿蛋白结果相关性。结果 35例患者24 h尿蛋白水平(351±116) g/24 h,〖JP〗直线回归分析显示尿蛋白与尿肌酐比值与24 h尿蛋白水平呈正相关(R=0897,Plt;001)。结论 尿蛋白与尿肌酐比值可能是一个重要的用于子痫患者尿蛋白筛查的指标。【Abstract】 Objective To investigate the diagnostic significance of urinary spot protein:creatinine ratio in Eclampsia.Method Thirtfive pregnant patients suffering from eclampsia with average age of (2681±639) years old were enrolled in this study.All patients were examined both urinary protein over 24 hours and urinary spot protein:creatinine ratio. The correlation between urinary protein over 24 hours to urinary spot protein:creatinine ratio with linear regression were analyzed. Result The rinary protein of 35 patients over 24 hours were (351±116) g/24 h,meanwhile the urinary spot protein:creatinine ratio were (0345±017) g/mmol. With linear regression, urinary spot protein:creatinine ratio had a positive correlation with the data of urinary protein over 24 hours (R=0897,Plt;001). Conclusion The spot protein:creatinine ratio is a reasonable test for detecting proteinuria in eclampsia pregnancy.