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find Author "张宜" 2 results
  • Research progress of the donor factors and experimental factors affecting adipogenic differentiation of adipose derived stem cells

    Objective To summarize the donor factors and experimental factors that affect adipogenic differentiation of adipose derived stem cells, so as to provide reference for adipogenic differentiation of adipose derived stem cells. Methods The related research literature about donor factors and experimental factors affecting adipogenic differentiation of adipose derived stem cells in recent years was extensively reviewed and summarized. Results There are a lot of donor factors and experimental factors affecting adipogenic differentiation of adipose derived stem cells, but some of the factors are still controversial, such as donor age, health status, adipose tissue of different parts, and so on. These factors need to be further studied. Conclusion The donor factors and experimental factors that affect adipogenic differentiation of adipose derived stem cells should be deeply studied and the controversial issues should be clarified to lay a solid foundation for the application of adipose derived stem cells in adipose tissue engineering.

    Release date:2017-11-09 10:16 Export PDF Favorites Scan
  • 纳米炭染色结直肠癌淋巴结分站对比研究

    目的探究纳米炭染色对结直肠癌淋巴结示踪的规律以及对转移淋巴结检出的影响。方法回顾性收集2022年4月至2023年9月期间于重庆医科大学附属第一医院胃肠外科接受腹腔镜结直肠癌根治性手术及术前行肿瘤纳米炭标记的92例患者的标本。新鲜标本淋巴结按第一站、第二站及第三站分检,各站又分为染色组和未染色组。比较各组间及组内不同站不同染色程度淋巴结的差异。结果共纳入92例患者,共分检出淋巴结2 859枚,其中转移淋巴结66枚(2.3%),未转移2 793枚(97.7%);黑染淋巴结2 167枚(75.8%),未染色692枚(24.2%)。淋巴结染色率从第一到第三站逐渐递增(P<0.017);第一站和第二站转移淋巴结的染色率比同站所有淋巴结染色率低(χ2=23.959,P<0.001;χ2=7.187,P=0.007),但在第三站中差异无统计学意义(χ2=1.155,P=0.283);第一站和第二站染色淋巴结转移率小于未染色淋巴结(χ2=26.224,P<0.001;χ2=7.520,P=0.006),但第三站中差异无统计学意义(χ2=1.232,P=0.267)。结论纳米炭淋巴结示踪效果随着淋巴回流逐渐增强。在第一站和第二站,其对于转移淋巴结的显示缺乏特异性,手术及分检过程中应更关注未染色淋巴结。在第三站淋巴结中,能够更有效地示踪转移淋巴结,可按染色淋巴结进行针对性地淋巴结清扫。

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