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find Author "张明礼" 2 results
  • Effect of intraoperative autotransfusion on erythrocytes in coronary artery bypass grafting

    Objective To explore ability of deformation ,small deformation, orientation and in vivo half-life of erythrocytes following intraoperative autotransfusion by ZITI-3000 cell saving system (Jingjing medical facility corporation, Beijing). Methods Twenty consecutive patients undergoing scheduled off-pump coronary artery bypass grafting (CABG) were divided into two groups according to intraoperative autotransfusion, experimental group(n=10): intraoperative autotransfusion was performed; control group (n=10): intraoperative autotransfusion wasn’t used. Laser diffractometer was used to measure deformation index(DI), small deformation index[(DI)d.max], and orientation index [(DI)or.max],and chromium51 istope labeling technique was used to measure half-life of erythrocytes (51C1/2) of processed and unprocessed in vivo. Results There were no significant difference in DI, (DI)d.max, (DI)or.max and 51C1/2 in vivo between experimental group and control group. Conclusion Intraoperative autotransfusion has no significant effect on erythrocytes’s ability of DI, (DI)d.max, (DI)or.max and 51C1/2 in vivo in off-pump CABG.

    Release date:2016-08-30 06:28 Export PDF Favorites Scan
  • 术中自体血液回收对体外循环术后全身性炎性反应的影响

    目的 探讨在体外循环手术中使用洗涤式自体血液回收机(ATS)对术后全身性炎性反应的影响.方法 将择期体外循环冠状动脉旁路移植术(CABG)的12例患者随机分为两组(每组6例),实验组:将手术野渗血和停机后机血混合经ATS处理后回输;对照组:将停机后机血直接回输.于围手术期测定两组补体终末复合物(sC5b-9)、白细胞介素-6(IL-6)等炎性因子指标.实验组分别测定ATS处理前后炎性因子指标. 结果 实验组回收血经ATS处理后红细胞压积(HCT)明显升高(Plt;0.01),sC5b-9、肿瘤坏死因子-α(TNF-α)和IL-6水平显著降低(Plt;0.05).停机6小时、24小时和48小时,实验组sC5b-9变化率均低于对照组(Plt;0.05),停机48小时,实验组IL-6变化率低于对照组(Plt;0.05),术后两组TNF-α水平以及变化率差别无显著性意义;停机48小时,实验组中性粒细胞(PMN)显著低于对照组(Plt;0.01). 结论 在体外循环手术中使用ATS回收术野渗血和停机后机血可以去除绝大部分炎性介质,回输后可以降低术后部分炎性介质的水平,减轻体外循环术后的炎性反应.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
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