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find Author "张雪飞" 4 results
  • Hand-Suture versus Stapling Anastomosis in the Incidence of Anastomotic Leakage Following Esophagogastrostomy: A Systematic Review

    Objective To assess the effectiveness and safety of hand-suture vs. stapling anastomosis in esophagogastrostomy. Methods The following databases such as CBM (1978 to February 2012), VIP (1989 to February 2012), CNKI (1994 to February 2012), WanFang Data (1980 to February 2012), The Cochrane Library, PubMed (1966 to February 2012), EMbase (1974 to February 2012), and relevant webs of clinical trials were searched to collect the randomized controlled trials (RCTs) and quasi-RCTs about hand-suture vs. stapling anastomosis in the incidence of anastomotic leakage following esophagogastrostomy. Moreover, relevant references and grey literature were retrieved on web engines including Google Scholar and Medical Martix, and the Chinese periodicals e.g. Chinese Journal of Oncology were also handsearched. According to the inclusion and exclusion criteria, the literature, was screened, the data were extracted, and the quality of the included studies was assessed. Then meta-analysis was conducted using RevMan 5.0 software. Results A total of 9 RCTs involving 2 202 patients were included. The result of meta-analysis was as follows: the incidence of anastomotic leakage in the stapling anastomosis group was lower than that in the hand-suture anastomosis group (OR=0.43, 95%CI 0.26 to 0.71, Plt;0.01). Conclusion Stapling anastomosis is superior to hand-suture anastomosis in reducing the incidence of anastomotic leakage following esophagogastrostomy. For the limited quality and quantity of the included studies, this conclusion has to be further proved by more high-quality studies.

    Release date:2016-09-07 10:58 Export PDF Favorites Scan
  • 纳米炭染色结直肠癌淋巴结分站对比研究

    目的探究纳米炭染色对结直肠癌淋巴结示踪的规律以及对转移淋巴结检出的影响。方法回顾性收集2022年4月至2023年9月期间于重庆医科大学附属第一医院胃肠外科接受腹腔镜结直肠癌根治性手术及术前行肿瘤纳米炭标记的92例患者的标本。新鲜标本淋巴结按第一站、第二站及第三站分检,各站又分为染色组和未染色组。比较各组间及组内不同站不同染色程度淋巴结的差异。结果共纳入92例患者,共分检出淋巴结2 859枚,其中转移淋巴结66枚(2.3%),未转移2 793枚(97.7%);黑染淋巴结2 167枚(75.8%),未染色692枚(24.2%)。淋巴结染色率从第一到第三站逐渐递增(P<0.017);第一站和第二站转移淋巴结的染色率比同站所有淋巴结染色率低(χ2=23.959,P<0.001;χ2=7.187,P=0.007),但在第三站中差异无统计学意义(χ2=1.155,P=0.283);第一站和第二站染色淋巴结转移率小于未染色淋巴结(χ2=26.224,P<0.001;χ2=7.520,P=0.006),但第三站中差异无统计学意义(χ2=1.232,P=0.267)。结论纳米炭淋巴结示踪效果随着淋巴回流逐渐增强。在第一站和第二站,其对于转移淋巴结的显示缺乏特异性,手术及分检过程中应更关注未染色淋巴结。在第三站淋巴结中,能够更有效地示踪转移淋巴结,可按染色淋巴结进行针对性地淋巴结清扫。

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  • Evaluation of the implementability of traditional Chinese medicine clinical practice guidelines in paediatrics

    ObjectiveTo evaluate the implementability of traditional Chinese medicine (TCM) guidelines in the field of paediatrics. MethodsWe searched the paediatrics-related TCM guidelines published in CNKI, WanFang Data, VIP, SinoMed and PubMed databases, and related websites from inception to November 1, 2023. The implementability of the included guidelines was evaluated using the clinical practice guideline implementability assessment tool. ResultsA total of 47 guidelines were included, covering 37 paediatric diseases and recommending 27 TCM therapies, including TCM decoction, Chinese patent medicines, acupuncture, paediatric massage, and acupoints. The results of the guideline accessibility evaluation showed that, in terms of the overall quality of accessibility, 5 guidelines (10.6%) were of high grade, 12 guidelines (25.5%) were of medium grade, and 30 guidelines (63.8%) were of low grade. With the exception of accessibility (multi-channel access methods) and communicability, which was of high quality, there is room for improvement in all areas, particularly in the areas of applicability and ease of recognition. ConclusionThe overall quality of implementability of the included paediatric TCM guidelines was low, and it is recommended that in the process of developing paediatric TCM guidelines in the future, we focus on improving the quality of implementability of the guidelines themselves from the source, so as to promote the implementation and application of the guidelines.

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  • Registration status and characterization of clinical trial registries in traditional medicine

    Objective To analyze the current research status, characteristics and development trend of traditional medicine-related clinical trials registration, and to provide ideas and directions for further development of traditional medicine clinical trials. Methods The International Traditional Medicine Clinical Trial Registry (ITMCTR) database was searched by computer from inception to June 30, 2024, with unlimited trial registration status, to collect all the clinical trials on traditional medicine, and analyzed in terms of the basic information of the trials, the diseases studied and the interventions. Results A total of 4 349 clinical trials related to traditional medicine were included, with the number of registrations peaking in the second half of 2020, and showing a steady upward trend after 2023. The studies conducted covered a total of 47 countries/regions, led by Beijing, Shanghai, Guangdong, Sichuan, and Zhejiang provinces, accounting for 69.72% of the total, and included 13 overseas regions. The financial support for the studies was dominated by local government funds in various provinces and cities, accounting for 29.66%. Disease types studied were mainly circulatory system diseases, musculoskeletal system or connective tissue diseases, and tumor diseases, accounting for 29.91% of the total. 3 751 (86.3%) clinical trials were interventional studies, of which randomized parallel control was predominant, and there were 213 large-sample studies with a sample size of more than 1 000 cases. A total of 20 types of interventions were involved, of which 1 114 (29.86%) clinical trials utilized oral herbal soup/granule interventions. Conclusion Clinical trial enrollment in traditional medicine has increased overall, but with significant geographic unevenness. Oral herbal soup/granule interventional studies are the mainstream hotspots. It is recommended to strengthen international cooperation, enrich the types of interventions, refine the trial design, and raise the awareness of researchers about the registration of high-quality traditional medicine clinical trials.

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