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find Keyword "悬浮红细胞" 2 results
  • 库存悬浮红细胞预处理对婴幼儿预充液中血糖、乳酸及钾离子的影响

    目的 观察库存悬浮红细胞预处理后对婴幼儿预充液中血糖、乳酸及钾离子浓度的影响,及对婴幼儿生理代谢的影响。 方法 2010年2月至2011年3月解放军第452医院收治40例先天性心脏病婴幼儿,按预充前是否清洗库存悬浮红细胞,将其分为两组,悬浮红细胞清洗组(清洗组,n=20):男11例,女9例;年龄(17.82±6.11)个月;在体外循环(CPB)中预充前采用血液回收机(cell saver)对库存悬浮红细胞进行清洗预处理;未清洗组(n=20):男6例,女14例;年龄(16.63±4.45)个月;在应用库存悬浮红细胞预充前未经清洗。两组在预充前(清洗组在库存悬浮红细胞清洗前、清洗后)、预充后、CPB前并行期、主动脉阻断后5 min、停机时分别检测血糖、血清乳酸和血钾离子浓度。 结果 清洗组库存悬浮红细胞清洗后血糖、乳酸和钾离子浓度明显低于清洗前(P<0.05)。在CPB各时间点清洗组血糖[主动脉阻断后5 min: (4.50±0.65) mmol/L vs. (5.78±0.62) mmol/L,t=5.308,P=0.001]和乳酸浓度 [主动脉阻断后5 min:(1.86±0.21) mmol/L vs. (2.89±0.45) mmol/L,t=1.504,P=0.001]明显低于未清洗组。除停机时,其余时间点清洗组钾离子浓度明显低于未清洗组 [主动脉阻断后5 min: (3.81±0.32) mmol/L vs. (4.44±0.51) mmol/L,t=3.588,P=0.011]。 结论 采用血液回收机(cell saver)清洗后的含库存悬浮红细胞预充液中的血糖、乳酸、钾离子浓度明显降低至生理范围内,可显著提高婴幼儿CPB的安全性。

    Release date:2016-08-30 05:45 Export PDF Favorites Scan
  • Impact of infusion of red blood cell suspension at different perioperative periods in patients with valvular heart disease

    Objective To investigate the impact of red blood cell suspension infusion across various perioperative periods on patients with valvular heart disease. Methods The patients with valvular heart disease admitted to Tianjin Chest Hospital from 2018 to 2020 were selected. Based on the timing of perioperative red cell suspension infusion, patients were categorized into three groups: a group 1 receiving intraoperative red cell suspension infusion, a group 2 receiving red cell suspension infusion within 24 hours after entering the ICU, and a group 3 receiving red cell suspension infusion at both time points. Clinical data, laboratory results, perioperative blood component infusion volume, and other relevant parameters were systematically recorded. After propensity score matching, the differences in different variables among the three groups were compared. Results After propensity score matching, 102 patients were enrolled, including 5 males and 50 females, with an average age of 61.74±10.58 years. There were 34 patients in each group. The preoperative hemoglobin (Hb) value of the group 2 was significantly higher than that of the group 1 and the group 3, and the amount of red cell suspension and autoblood transfusion was the lowest (P<0.05). In the group 1, Hb was the highest after surgery, Hb was the highest within 24 hours after surgery, HCT was the highest within 24 hours after surgery (P<0.05). The group 1 had the lowest plasma, platelet and cryoprecipitate infusion volumes, and the shortest cardiopulmonary bypass time, aortic occlusion time, postoperative ICU stay and hospital stay, and the least blood loss, total drainage volume (P<0.05). The difference between postoperative Hb and preoperative △Hb1 was significantly increased in the group 1 (P<0.05). Conclusion The intraoperative infusion of suspended red blood cells in patients with heart valves can be used to indicate to clinicians that patients have a better prognosis at discharge, review and follow-up.

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