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find Author "房学东" 3 results
  • 远端胃切除术后胃瘫综合征的危险因素分析

    目的探讨远端胃切除术后胃瘫综合征发生的高危因素及与不同疾病和手术术式的关系。 方法回顾性分析吉林大学中日联谊医院胃肠外科2011年1月至2013年12月期间484例行远端胃切除手术病例的临床资料,对年龄、性别、术前低蛋白血症和流出道梗阻、疾病类型、手术方式等引起胃瘫综合征相关危险因素进行分析。 结果484例患者术后发生胃瘫综合征21例(4.3%)。患者年龄(P<0.01)、术前流出道梗阻(P<0.05)及重建方式(P<0.05)与术后胃瘫综合征的发生有关。 结论高龄、术前流出道梗阻和胃空肠吻合术是诱发胃瘫综合征的高危因素。

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  • Research progress of chemokines and their receptors in gastric cancer

    Objective To understand role of chemokines and their receptors in pathogenesis, progression, and metastasis of gastric cancer, and to provide a better approach for diagnosis and treatment of gastric cancer. Method The literatures about the relationship between chemokines and their receptors and gastric cancer were reviewed. Results There were about 50 various chemokines and their receptors abnormally expressed in the tumor microenvironment. The main types related gastric cancer were the CXC, CC and CX3C chemokines and their receptors, which could promote the proliferation, invasion, and metastasis of the gastric cancer through several pathways like mTOR pathway, JAK2-STAT3 pathway, etc.. Conclusions Chemokines and their receptors play an important role in occurrence and development of gastric cancer. Further studies on chemokines and their receptors will not only assist in early diagnosis of gastric cancer, as well as estimation of clinical prognosis, but also provide an intervention target for gastric cancer.

    Release date:2018-03-13 02:31 Export PDF Favorites Scan
  • Comparison of short-term effect between laparoscopic and open Miles operations for lower rectal carcinoma

    Objective To evaluate short-term effect of laparoscopic and open Miles operations for lower rectal carcinoma. Methods A total of 119 patients with lower rectal carcinoma were retrospectively collected from March 2012 to March 2017 in this hospital, among which 65 were in the laparoscopic operation group and 54 in the open operation group. The perioperative data, pathological results, recovery courses, and complications were compared between the two groups. Results Compared with the open operation group, the laparoscopic group showed a longer operation time (t=6.035, P=0.002), quicker bowel function recovery (t=4.919, P<0.001), faster off-bed activity (t=2.221, P<0.001), and shorter hospital stay time (t=3.795, P=0.025). The intraoperative blood loss (t=0.154, P=0.698) and the number of harvested lymph nodes (t=0.532, P=0.595) were similar between the two groups. The laparoscopic operation group showed a significant lower total complication rate (χ2=7.174, P=0.009) as compared with the open operation group, but the incision infection, urinary tract injury, lung infection, thrombosis of lower extremities, etc. had no significant differences between the two groups (P>0.050). Conclusion Laparoscopic Miles operation improves postoperative recovery and reduces postoperative complications as compared with open approach in treatment of lower rectal cancer, with similar oncological and short-term results.

    Release date:2018-07-18 01:46 Export PDF Favorites Scan
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