目的探讨胃癌穿孔的手术时机及术式选择。方法对我院1985年1月至2000年12月间急诊收治的64例胃癌穿孔患者的资料进行回顾性分析。结果保守治疗后行择期手术5例； 59例行急诊手术，其中行根治性切除术22例，姑息性切除术10例，穿孔修补后3周内二期行根治性手术6例，行单纯穿孔修补术14例，穿孔修补+短路手术7例。本组手术后30天内死亡6例，死亡率为9.4%，58例中获随访52例，随访5年，失访6例，其中根治性手术、姑息性切除、单纯穿孔修补和穿孔修补+短路手术者平均生存期分别为31个月、18个月、5个月和7个月。结论合理的手术时机及术式选择是延长患者生命和提高患者生存质量的关键所在。
Abstract: Ventricular septal rupture is a rare complication of acute myocardial infarction, but it can easily lead to such complications as acute heart failure and cardiac shock with sinister prognosis. Surgical treatment is a fundamental measure to improve the prognosis, and the selection of operation time is a key factor. The basic guiding principles of operation timing are as follows. Those patients who have acute heart failure and/or cardiac shock soon after the onset of ventricular septal rupture, and can not be controlled by nonsurgery therapy and are also unable to tolerate surgery, will die soon. For them, surgery treatment cannot be implemented because they have missed the optimal operation time. For those whose perforation was so small that they can be stably controlled by nonsurgery therapy, surgery treatment can be postponed for 1 to 4 weeks. However, emergency operation should be performed in time once the condition of the patients becomes unstable. For others, no matter in what state they are, surgical treatment should be implemented immediately.
To compare the effectiveness of the operations in treatment of thoracolumber spine fracture and dislocation with spinal cord injury in different periods. Methods Between June 2003 and June 2008, 80 cases of thoracolumber spine fracture and dislocation with spinal cord injury were treated. There were 52 males and 28 females with an average age of 37.6 years (range, 28-49 years). According to different operative time, they were divided into 2 groups by randomized controlled study: group A (n=39, operation was performed within 24 hours) and group B (n=41, operation was performed at 3-7 days). In group A, there were 23 cases of degree I-II (group A1), 16 cases of degree III-V (group A2) according to Meyerding standard, including 17 cases of grade A, 7 cases of grade B, 9 cases of grade C, and 6 cases of grade D according to Frankel scoring system. In group B, there were 21 cases of degree I-II (group B1) and 20 cases of degree III-V (group B2), including 20 cases of grade A, 7 cases of grade B, 11 cases of grade C, and 3 cases of grade D. All cases were treated with posterior spinal cord decompression and reduction, with internal fixation by pedicle screw-rod system and transforamen lumbar interbody fusion. Results The blood loss was (407.4 ± 24.3) mL in group A1 and (397.4 ± 8.2) mL in group B1, showing no significant difference (t=1.804, P=0.078); the blood loss was (1 046.9 ± 128.6) mL in group A2 and (494.4 ± 97.7) mL in group B2, showing significant difference (t=14.660, P=0.000). All 80 patients were followed up 2 years to 2 years and 6 months (mean, 2 years and 3 months) with satisfactory results in spinal cord decompression and reduction, and bony fusion was achieved at 12 months. There was no significant difference in the vertebral canal volume, vertebral height, and Cobb angle at both pre- and postoperation between 2 groups (P gt; 0.05). No loosening or breakage of screws and rods occurred. At 12 months after operation, the cure rates were 47.83% (11/23) in group A1 and 19.05% (4/21) in group B1, showing significant difference (χ2=4.046, P=0.044); the cure rates were 12.50% (2/16) in group A2 and 10.00% (2/20) in group B2, showing no significant difference (χ2=0.056, P=0.813). There was no significant difference (χ2=0.024, P=0.878) in the cure rates in the patients at grades A and B before operation between group A (12.50%, 3/24) and group B (11.11%, 3/27); but there was significant difference (χ2=5.992, P=0.014) in the cure rates in the patients at grades C and D before operation between group A (66.67%, 10/15) and group B (21.43%, 3/14). Conclusion Emergency operation of posterior pedicle screw-rod system for treatment of thoracolumber spine fracture and dislocation with spinal cord injury can provide good reduction, rigid fixation, and high fusion rate, so it is asafe and effective treatment method.
Objective To provide references for clinical management of patients with orbital blow-out fractures. Methods Evidence was retrieved from The Cochrane Library online (Issue 1, 2009), ACP online, NGC (1998 to March 2009), PubMed (January 1950 to February 2009), and CBM (1994 to February 2009). The collected evidence was then graded. Results After preliminary research, we identified 12 relevant articles: either retrospective studies or comments from specialists. They studied orbital soft tissue entrapment, diplopia, enophthalmos, or severe oculocardiac reflex in the surgical indications of orbital blow-out fractures. Most of the literature suggested less than five days after the injury incursion for children and less than two weeks for adults was the optimal time to undergo operation. However, advanced surgery was still a good option for the patients that could not undergo early surgery. With regard to the use of poly-pdioxanon- foil and titanium-dynamic mesh, two randomized controlled trials suggested that the former was superior to the latter. Conclusion The application of this surgery should be cautious because of low levels of evidence. Individual therapies should be used after close consideration of clinical characteristics.
Objective To discuss the optimal time for operation in patients with malignant middle cerebral artery (MCA) syndrome. Method The relation between effectiveness and operating time was analyzed in 47 patients to compare the effects of early and delayed operation by SPSS10.0. Results Among 27 patients undergoing early operation, 18 were cured or restored, 4 seriously disabled and 5 died. While among 20 patients undergoing delayed operation, only 9 were cured or restored, 4 seriously disabled and 7 died. The prognosis of delayed operation group was worse than that of early operation group. Conclusions Selecting the optimal time to operate may decrease the mortality and morbidity of MCA syndrome.
Objectives To identify the effect of procalcitonin (PCT) on the choice of operating time for severe acute pancreatitis and assessment of postoperative complications by monitoring the level of serum PCT and recording the incidence of postoperative complications. MethodsNinety-three patients who underwent debridement and drainage of infected necrosis from Sep. 2009 to Dec. 2011 were included. Serum PCT was tested on the day of admission (0 day), one week after admission, one day before surgery, one day after surgery, and one week after surgery. According to the level of serum PCT, all the 93 patients were divided into 3 groups:low level group (PCT < 2 ng/mL), middle level group (PCT 2-10 ng/mL), and high level group (PCT > 0 ng/mL). Postoperative complications were also recorded. ResultsThe incidence of postoperative complications was 19.4% (18/93). There were postoperative bleeding in 13 patients, intestinal fistula in 14 patients, pancreatic fistula in 18 patients, pulmonary infection in 4 patients, residual abscess in 10 patients; re-operation in 15 patients, and death in 8 patients (the death rate was 8.6%). Besides the pulmonary infection, and grade A and C of pancreatic fistula, the incidence of various complications in middle level group and high level group were lower than low level group (P < 0.05). Patients with complications had significantly higher PCT value in one week after admission than onset (P < 0.05). PCT value was higher in the patients with intestinal fistula and residual abscess on one day after operation than on one day before operation (P < 0.05). Patients who died or with re-operation had significantly higher PCT value in one week after operation than on one day after operation (P < 0.05). In the dead patients, the serum PCT sustained at a high level after operation. ConclusionsThe level of serum PCT is correlated with the incidence of postoperative complications. Dynamic monitoring the level of serum PCT can guide the choice of operative time and assessment of postoperative complications including intestinal fistula, pulmonary infection, and death, which can greatly improve the prognosis of SAP.
ObjectiveTo evaluate optimal surgical timing of high ligation and ambulatory phlebectomy in treatment of primary great saphenous varicose vein. MethodsThe patients who met the inclusion criteria were divided into simple varicose vein (C2) group and soft tissue complications (C3-C4) group.All the patients were received high ligation and ambulatory phlebectomy.The surgery-related indexes,hospital costs,improvement of quality of life,postoperative recurrence rate were observed. ResultsAll the operations were successful.The operative time,the number of operative incision,and the hospital costs in the C2 group were significantly less than those in the C3-C4 group (P<0.05).The total postoperative complications rate in the C2 group was significantly lower than that in the C3-C4 group (P<0.05).The postoperative AVVQ score on month 3 in the C2 group was significantly lower than that in the C3-C4 group (P<0.05).The postoperative recurrence rate on month 3 had no statistical significance between these two groups (P>0.05). ConclusionsEarly stage (C2) is the optimal surgical timing of primary great saphenous varicose vein,benefits of surgery and health economics in early stage are significantly better than those in mid-advanced stage (C3-C4).It is suggested that surgery should be underwent at early stage in patients with primary great saphenous varicose vein.